Subject(s)
Humans , Male , Female , Mental Health Services/ethics , Mental Health Services/legislation & jurisprudence , Community Mental Health Centers/organization & administration , Mental Health/ethics , Mental Health/trends , Primary Health Care/methods , Primary Health Care/trends , Delivery of Health Care/organization & administration , Delivery of Health Care/standards , Primary Health Care/standards , Mental Health Services/statistics & numerical data , Mental Health Services/standards , Mental Health Services/trends , Mental Health Services , Community Mental Health Centers/economics , Primary Health Care/organization & administration , Primary Health CareABSTRACT
No disponible
No disponible
Subject(s)
Male , Female , Aged , Humans , Elder Abuse/diagnosis , Elder Abuse/therapy , Risk Factors , Interviews as Topic/methodsABSTRACT
No disponible
Subject(s)
Aged , Humans , Elder Abuse , Elder Abuse/prevention & control , Primary Health CareABSTRACT
Some thoughts on primary care and Ill-treatment of women (AU)
Subject(s)
Middle Aged , Humans , Child , Female , Adult , Primary Health Care , Battered Women , Algorithms , Domestic Violence , Spain , Risk Factors , Surveys and QuestionnairesABSTRACT
No disponible
Subject(s)
Humans , Physicians, Family , Marriage , Physician's Role , Spouse Abuse , Domestic Violence , Family Characteristics , Family TherapyABSTRACT
The objective was to evaluate the effect of biliary salt depletion on morphology and function of the exocrine pancreas. Cholestyramine (15 g/day) was given during fifteen days to male Wistar rats in order to evaluate changes in pancreas weight as well as in enzymatic content of pancreatic tissue and duodenal juice (amylase, lipase and trypsinogen); in duodenal juice, bile salt concentration was also measured; Moreover ultrastructure of the exocrine pancreas was studied. Our results show an increase in pancreas weight in rats treated with cholestyramine, with a significant increase of amylase (p < 0.05) and trypsinogen in pancreatic tissue (p < 0.01), and of lipase in duodenal juice (p < 0.05). Ultrastructural changes were absent. It is concluded that cholestyramine, probably through a bile salt depletion, stimulates pancreatic function and growth, as well as lipase secretion.
Subject(s)
Cholestyramine Resin/pharmacology , Pancreas/drug effects , Pancreas/metabolism , Amylases/analysis , Amylases/drug effects , Animals , Duodenum , Intestinal Secretions/drug effects , Intestinal Secretions/enzymology , Lipase/analysis , Lipase/drug effects , Male , Pancreas/enzymology , Pancreas/ultrastructure , Rats , Rats, Wistar , Trypsinogen/analysis , Trypsinogen/drug effectsABSTRACT
AIMS: To assess the level of immunity in a healthy population to the hepatitis A virus (HAV), according to age groups and in an urban health area. DESIGN: Transversal random prospective study of a sample of the population found by letters. SITE. Primary Care Centre covering the population of an urban health area in Valladolid. PATIENTS OR OTHER PARTICIPANTS: Random sample of 726 people with an adjustment as to sex and age according to the area's average, in line with the full census of the above area. The sample was 95% trustworthy, with a 3% margin of error. People with serious illness at the time of the study were excluded. MEASUREMENTS AND MAIN FINDINGS: We carried out a social-health count. We established the anti-HAV titer after its detection by enzyme immunoanalysis (HAVAB EIA Abbott); the titers were inferred from the absorbances relating then to that of a a "pool" of serums with very high titers. 69.9% (standardised rate) gave positive. The highest titers were presented in people between 31 and 50 (29.7 +/- 47.0), with significant differences both for lower (17.0 +/- 15.7) and higher (15.7 +/- 19.8) age groups (p. 0.001 for both). CONCLUSIONS: The highest anti-HAV titers corresponded to people in the middle age-group, with a subsequent dropping-off. This could suggest a greater susceptibility to HAV infection in the older person.
Subject(s)
Hepatitis Antibodies/blood , Hepatovirus/immunology , Urban Population , Adolescent , Adult , Age Factors , Aged , Child , Female , Hepatitis A/epidemiology , Hepatitis A/immunology , Humans , Male , Middle Aged , Prevalence , Prospective Studies , Random Allocation , Seroepidemiologic Studies , Sex Factors , Spain/epidemiology , Urban Population/statistics & numerical dataABSTRACT
In order to assess the experimental level of enzymatic content in exocrine pancreas of cirrhotic rats, cirrhosis was induced with administration of thioacetamide (50 mg/kg) during ten weeks to male Wistar rats with an initial average weight of 350 g. Contents of amylase, lipase and trypsinogen were determined in pancreatic tissues and amylase, lipase and biliary salts in duodenal juice obtained by cannulation and perfusion with physiologic serum. A higher presence of trypsinogen and amylase was detected in pancreatic tissues, and of lipase in the duodenal juice, with a trend, although insignificant, towards a decrease in biliary salts among the cirrhotic group. No changes were observed in the morphologic study. The hypothesis that a deficit of biliary salts in experimental cirrhosis could be responsible of the enzymatic increase in the pancreatic tissue and, in particular, of the selective excretion of lipase, is discussed.
