ABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Immunoglobulin E , Hypersensitivity, Immediate/complications , Hypersensitivity, Immediate/diagnosis , Brassicaceae/immunology , Immunoglobulin E/immunology , Hypersensitivity, Immediate/immunologyABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Hypersensitivity, Immediate/diagnosis , Hydrocortisone/adverse effects , Drug Hypersensitivity/diagnosis , Risk FactorsABSTRACT
Morniflumate is the morpholinoethyl ester of niflumic acid, a non-steroidal anti-inflammatory drug, derived from nicotinic acid. We studied 112 patients who had experienced cutaneous reactions after using non-steroidal anti-inflammatory drugs. Only two of all the patients who underwent an oral challenge with morniflumate had a positive result to the test. By demonstrating the low incidence of reactions to morniflumate through oral challenges, we suggest that patients with non-steroidal anti-inflammatory drug hypersensitivity may tolerate this drug which would therefore be a useful alternative.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Niflumic Acid/analogs & derivatives , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Drug Eruptions/etiology , Female , Humans , Hypersensitivity, Immediate/etiology , Male , Middle Aged , Niflumic Acid/administration & dosage , Young AdultSubject(s)
Angioedema/chemically induced , Drug Eruptions/etiology , Hydrocortisone/analogs & derivatives , Immunoglobulin E/immunology , Reagins/immunology , Urticaria/chemically induced , Aged , Anaphylaxis/chemically induced , Anaphylaxis/immunology , Angioedema/immunology , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Bronchitis/drug therapy , Drug Eruptions/immunology , Female , Humans , Hydrocortisone/adverse effects , Hydrocortisone/immunology , Immunologic Memory , Injections, Intramuscular , Intradermal Tests , Male , Methylprednisolone Hemisuccinate , Sulfonamides , Time Factors , Urticaria/immunologySubject(s)
Allergens/immunology , Antigens, Plant/adverse effects , Food Hypersensitivity/etiology , Mentha/adverse effects , Respiratory Hypersensitivity/etiology , Adult , Allergens/adverse effects , Angioedema , Antigens, Plant/immunology , Antigens, Plant/isolation & purification , Eating , Female , Food Hypersensitivity/diagnosis , Humans , Immunoglobulin E/immunology , Immunoglobulin E/metabolism , Oils, Volatile/adverse effects , Plant Extracts , Plant Leaves/adverse effects , Respiratory Hypersensitivity/diagnosis , Skin TestsABSTRACT
We present the cases of 5 patients with a positive clinical history of cutaneous symptoms due to contact with latex products. A latex allergological assessment was made through skin prick tests (SPTs) both with commercial latex extracts and extemporaneous glove extracts, and serum-specific IgE to latex and glove-use tests. In addition, serum-specific IgE to recombinant allergens for Hevea brasiliensis was dosed. Molecular diagnostics in association with the glove-use test and, to a lesser extent, the SPTs with glove eluate are useful diagnostic tests to confirm the diagnosis of latex allergy in patients with mucocutaneous symptoms.
Subject(s)
Allergens/immunology , Antigens, Plant/immunology , Chitinases/immunology , Latex Hypersensitivity/diagnosis , Latex Hypersensitivity/immunology , Latex/immunology , Plant Proteins/immunology , Adult , Cross Reactions , Female , Hevea/immunology , Humans , Immunoglobulin E/blood , Male , Middle Aged , Skin TestsSubject(s)
Anti-Bacterial Agents/adverse effects , Coronary Vasospasm/chemically induced , Electrocardiography/drug effects , Anti-Bacterial Agents/administration & dosage , Coronary Vasospasm/diagnosis , Coronary Vasospasm/physiopathology , Diagnosis, Differential , Follow-Up Studies , Humans , Infusions, Intravenous , Male , Middle Aged , Penicillanic Acid/administration & dosage , Penicillanic Acid/adverse effects , Penicillanic Acid/analogs & derivatives , Piperacillin/administration & dosage , Piperacillin/adverse effects , Piperacillin, Tazobactam Drug Combination , Pneumonia, Bacterial/drug therapy , Syndrome , beta-Lactamase InhibitorsABSTRACT
Acquired angioedema (AAE) with C1 inhibitor deficiency is often associated to B cell lymphoproliferative disorders or autoimmune diseases. We report a case of AAE associated with IgM anti-cardiolipin antibodies, with frequent edematous attacks, that disappeared completely after a slight immunosuppression and danazol therapy.
Subject(s)
Angioedema/immunology , Antibodies, Anticardiolipin/blood , Complement C1 Inactivator Proteins/deficiency , Immunoglobulin M/blood , Aged , Angioedema/diagnosis , Angioedema/drug therapy , Azathioprine/therapeutic use , Complement C1 Inhibitor Protein , Danazol/therapeutic use , Female , Humans , Immunosuppressive Agents/therapeutic use , Ticlopidine/therapeutic use , Treatment OutcomeSubject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Conjunctivitis, Allergic/chemically induced , Dipyrone/adverse effects , Hypersensitivity, Immediate/chemically induced , Rhinitis/chemically induced , Administration, Oral , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Aspirin/administration & dosage , Aspirin/adverse effects , Conjunctivitis, Allergic/diagnosis , Conjunctivitis, Allergic/immunology , Dipyrone/administration & dosage , Humans , Hypersensitivity, Immediate/diagnosis , Hypersensitivity, Immediate/immunology , Male , Middle Aged , Nasal Provocation Tests/methods , Rhinitis/diagnosis , Rhinitis/immunology , Rhinomanometry/methods , SpirometrySubject(s)
Food Hypersensitivity/diagnosis , Food Hypersensitivity/immunology , Octopodiformes/immunology , Adult , Animals , Female , Humans , Skin TestsABSTRACT
Tomato atopy patch test in adult atopic dermatitis.
Subject(s)
Dermatitis, Atopic/diagnosis , Food Hypersensitivity/diagnosis , Skin Tests/methods , Solanum lycopersicum/adverse effects , Adult , Dermatitis, Atopic/complications , Dermatitis, Atopic/immunology , Enzyme-Linked Immunosorbent Assay , Female , Food Hypersensitivity/complications , Food Hypersensitivity/immunology , Humans , Immunoglobulin E/blood , Male , Middle Aged , Sensitivity and SpecificityABSTRACT
Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Only one of 82 patients who were treated with etoricoxib reported reactions. We can conclude that etoricoxib shows a high long-term tolerability in patients with non-steroidal anti-inflammatory drug hypersensitivity.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Cyclooxygenase 2 Inhibitors/therapeutic use , Drug Hypersensitivity/etiology , Pyridines/therapeutic use , Sulfones/therapeutic use , Administration, Oral , Adolescent , Adult , Aged , Aged, 80 and over , Cyclooxygenase 2 Inhibitors/administration & dosage , Cyclooxygenase 2 Inhibitors/adverse effects , Etoricoxib , Female , Humans , Male , Middle Aged , Pyridines/administration & dosage , Pyridines/adverse effects , Retrospective Studies , Single-Blind Method , Sulfones/administration & dosage , Sulfones/adverse effects , Young AdultABSTRACT
The group of non-steroidal anti-inflammatory drugs (NSAIDs) is commonly involved in hypersensitivity reactions. In clinical practice the physician is often faced with the need to choose an alternative anti-inflammatory agent for a patient who has suffered a hypersensitivity reaction to a NSAID. The most common approach to choosing the safest NSAID is to perform a challenge test. Parecoxib is the first injectable COX-2 selective inhibitor indicated for the treatment of acute postoperative pain. The authors report the case of a patient with a history of cutaneous adverse reactions to different classes of NSAIDs, including selective COX-2 inhibitors, who underwent and tolerated challenge with parecoxib.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Cyclooxygenase 2 Inhibitors/adverse effects , Cyclooxygenase Inhibitors/therapeutic use , Drug Hypersensitivity/etiology , Isoxazoles/therapeutic use , Female , Humans , Middle AgedABSTRACT
Levocetirizine is the pharmacologically active enantiomer of cetirizine. It is a potent histamine H-1 receptor antagonist with anti-inflammatory and antiallergic properties. The review analyses the levocetirizine's properties in terms of safety and efficacy both in allergic rhinitis and urticarioid syndromes.
