Chronic Procrastination Among Iranians: Prevalence Estimation, Latent Profile and Network Analyses.

Procrastination is the deliberate, unjustified postponing of an intended course of action despite its costs or unfavorable effects. The present study used a self-report online survey and collected data from a large convenience sample of the general adult population (N = 2,076; females = 55.73%; Mage = 35.1 years [SD ± 12.7]) with diverse demographics. Following the ring-curve distribution, the results indicated a 15.4% prevalence rate of procrastination among the Iranian community, which was significantly higher among women and divorced individuals and lower among nomadic individuals and those with higher academic degrees. A latent profile analysis demonstrated two distinct profiles, one for procrastinators (high scores on chronic procrastination, psychological distress, neuroticism, and extraversion; and low scores on general self-efficacy, self-esteem, satisfaction with life, openness, agreeableness, and conscientiousness) and one for non-procrastinators (demonstrating a reverse pattern compared to procrastinators). Moreover, additional network analysis suggested that the examined networks were invariant across procrastination status and gender. The results indicate that procrastination differs by demographic characteristics and is associated with a unique psychological profile. However, none of the aforementioned key study variables were considered a potential vulnerability for procrastinators due to the finding that all variables were peripheral and none were central in the examined networks. Therefore, relying on the differences in mean scores on psychometric scales does not appear to be an optimal way of determining the most important variables in a therapeutic context when treating procrastination.

Reactance, Decisional Procrastination, and Hesitation: A Latent Class Analysis of Clutter Behavior.

During the 2019-2020 global pandemic, mandated time at home suggested engagement in personal projects, such as home decluttering. Clutter (an overabundance of possessions) may impede one's quality of life by interfering with space livability and social connections and prompting negative affect and financial problems. The present study explored action-state orientation, psychological reactance, and decisional procrastination with 227 American adults (M age = 49.9 years old). A latent class analysis tested for differences in cognition across groups. Results supported that persons who struggle with clutter reflect clusters or "classes" given their self-reported cognitive processes, with hesitant and indecisive participants experiencing greater negative impacts of clutter than action-oriented and decisive participants. Our findings suggested improving the decision-making and goal-directed capacities of those struggling with clutter may be effective as preventive and/or interventive strategies. Future research might consider when hesitation to initiate challenging tasks and indecision emerge in the decluttering timeline and how those who are prone to these cognitions may be supported in managing their personal possessions.

The Involvement in Alcoholics Anonymous Scale - Short Form: Factor Structure & Validation.

Background: The aim of this research was to examine the psychometrics of a short form version of the multidimensional Involvement in Alcoholics Anonymous scale (IAA-SF) by assessing the factor structure, internal consistency, and predictive validity. While there are several existing measures of involvement in Alcoholics Anonymous, many are either unidimensional or are limited in their ability to gather variation in the level of involvement in the different dimensions of 12-step programs. Objective: To achieve our aim, we used exploratory and principal axis factor analysis, correlation, and logistic regression with two unique and diverse samples. Longitudinal data were collected from a northern Illinois sample of 110 post-treatment adults, and cross-sectional data were from a random sample of 296 recovery home residents in the United States. Results: Results from the first sample suggested three exploratory factors (Principles Involvement, Social Involvement, and Spiritual Involvement) that were concordant with the proposed conceptualization and were then confirmed in the second sample. A 2nd order factor of global involvement was also found. All subscales demonstrated good to excellent internal consistency and were moderately associated with AA affiliation. Global and social involvement predicted greater odds of abstinence 2 years later, but principles and spiritual involvement did not. Conclusion: Overall results suggest the IAA- SF is a valid and reliable 12-item instrument for assessing involvement in the AA program, and the differential prediction suggests potential utility for a multidimensional approach to 12-step involvement.

Predictors of e-waste: Considerations for community psychology prevention and intervention.

E-waste, the overabundance of unused technology products, is a growing issue as new technology is rapidly innovated and our society promotes the need to always have the "latest and greatest" products. Community psychology, as a field, is concerned with the global climate crisis, and subsequently must be concerned with e-waste. This study tested predictors of individual's likelihood to recycle e-waste with 883 US adults (459 males, 420 females, 3 other/nonbinary; 62.7% 54-year-old or younger) through a crowdsourcing procedure. Similar to previous recycling literature, the present study found that personal norms, subjective norms, and perceived behavioral control positively predicted the likelihood for an individual to recycle; however, the present study provides further empirical evidence for these relationships and expands recycling literature by focusing on e-waste recycling. Implications for the field of community psychology with preventive and interventive actions are detailed.

Spiritual Awakening in 12-Step Recovery: Impact Among Residential Aftercare Residents.

Spiritually-based interventions in the form of 12-step programs are frequently offered as a part of substance use treatment programs in the United States. Programs based in the 12 steps guarantee that by working their program, an individual will undergo a process of transformation labeled a spiritual awakening. However, the impact of this experience on recovery factors and treatment adherence is unclear. The current study investigated adult residents (n = 115) who experienced a spiritual awakening attributed to 12-step group affiliation during their stay at residential aftercare facilities for substance use disorder. Self-efficacy and hope were greater for individuals who experienced a spiritual awakening versus those persons who did not experience awakening. Awakening was associated with greater affiliation to AA and decreased negative exit from the facility. Results revealed the potential for an awakening to improve treatment behavior and outcomes in a residential environment, as well as benefit an individual's personal recovery resources. Further theoretical and clinical implications are discussed.

Home Away from Home: Comparing Factors Impacting Migrants' and Italians Sense of Psychological Home.

Psychological home is an understudied concept within community psychology, especially focused on migrants. Previous literature on psychological home found a positive relationship with well-being and resilience in general populations and migrants. Studying psychological home in migrants may provide important tools to buffer various stresses associated with migration. The present study explored the relationship between psychological home and demographic factors, including dwelling type and situation between migrants (n = 132) and Italian citizens' population (n = 76). Results offer theoretical reasons explaining the differences in the meaning of home between migrant and non-immigrant populations.

Selective activation and expansion of regulatory T cells using lipid encapsulated mRNA encoding a long-acting IL-2 mutein.

Interleukin-2 (IL-2) is critical for regulatory T cell (Treg) function and homeostasis. At low doses, IL-2 can suppress immune pathologies by expanding Tregs that constitutively express the high affinity IL-2Rα subunit. However, even low dose IL-2, signaling through the IL2-Rß/γ complex, may lead to the activation of proinflammatory, non-Treg T cells, so improving specificity toward Tregs may be desirable. Here we use messenger RNAs (mRNA) to encode a half-life-extended human IL-2 mutein (HSA-IL2m) with mutations promoting reliance on IL-2Rα. Our data show that IL-2 mutein subcutaneous delivery as lipid-encapsulated mRNA nanoparticles selectively activates and expands Tregs in mice and non-human primates, and also reduces disease severity in mouse models of acute graft versus host disease and experimental autoimmune encephalomyelitis. Single cell RNA-sequencing of mouse splenic CD4+ T cells identifies multiple Treg states with distinct response dynamics following IL-2 mutein treatment. Our results thus demonstrate the potential of mRNA-encoded HSA-IL2m immunotherapy to treat autoimmune diseases.

Older Adults and Clutter: Age Differences in Clutter Impact, Psychological Home, and Subjective Well-Being.

Previous research found mixed results for clutter's impact on individuals' sense of home and subjective well-being in a variety of samples. In this retrospective cross-sectional study, archival data were utilized to examine the relationship between clutter, psychological home, and subjective well-being across two age categories, specifically older adults aged ≥65 (n = 225), and younger adults aged ≤64 (n = 225). Three moderation analyses used age categories as a moderator exploring the relationship between (a) clutter predicting psychological home, (b) psychological home predicting subjective well-being, and (c) clutter predicting subjective well-being. Results found that age categories significantly moderated the relationship between clutter and psychological home but did not moderate the other variable relationships.

Online and Academic Procrastination in Students With Learning Disabilities: The Impact of Academic Stress and Self-Efficacy.

The steady growth in the number of college students with learning disabilities (LD) increases the need to investigate their unique characteristics and behaviors in academia. The present study examined the differences in academic and online procrastination, academic stress, and academic self-efficacy between college students with and without LD. In addition, the relationship between these variables was examined. It was assumed that the difficulties experienced by college students with LD would lead them to increased levels of academic stress, and academic and online procrastination. The results showed significant differences in the levels of all variables except online procrastination between students with (n = 77) and without (n = 98) LD. Further analysis indicated that academic stress and academic self-efficacy mediated the link between LD and academic and online procrastination. These findings support the notion that during higher education, students with LD experience more difficulties than students without LD, which at times will lead them to increased levels of procrastination. However, further studies are needed to understand the nature of online procrastination in students with LD in higher education.

Unaccompanied migrant minors in Europe and U.S.: A review of psychological perspective and care challenges.

Unaccompanied migrant minors are youth under the age of 18 who migrate alone, traveling separately from both parents. These youth may be asylum seekers, recognized refugees, or other externally displaced persons. Unaccompanied migrant minors have become an increasingly prevalent global issue. However, this phenomenon might be better understood considering the peculiarities of their contexts, since there are differences related to specific conditions and reception systems. The present study reviewed and compared visually previously reported psychological perspective of unaccompanied migrant minor receiving services from select European countries and the U.S. Unaccompanied migrant minors create a challenge on a nation's care system because these minors are the most vulnerable group in the context of migration. Our explorative assessment suggested underlining similarities and differences between contexts, reflecting the unique needs of the unaccompanied migrants and proposed services and intervention models.

Time is on My Side-or Is It? Assessing How Perceived Control of Time and Procrastination Influence Emotional Exhaustion on the Job.

The job demands-control model (JDC) postulates that an increased control over work resources mitigates or "buffers" the positive association between job stressors and strainers. However, the inconclusive validation of the buffering hypothesis across multiple studies suggests the need for fresh approaches, both conceptual and methodological. We integrated aspects of the JDC framework and time management process models to construct a model that tested both the direct and indirect effects of the perceived control of time (PCT) on emotional exhaustion arising from workload demands. Furthermore, we tested whether procrastination tendencies moderated the benefits of PCT on work stressors and strains. Data were collected in an Internet survey with 356 US adult office workers obtained from Prolific. The results supported the buffering effect of PCT on emotional exhaustion. PCT both mediated and exerted direct effects on the relationship between workload and emotional exhaustion. Procrastination tendencies moderated PCT and, in turn, undermined high PCT ability to reduce emotional exhaustion. Overall, the findings suggested that giving workers more control over their time may reduce stress associated with demanding workloads. However, chronic procrastinators may benefit less from having more control over time resources if they are not provided with tools to help them self-regulate more effectively.

Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis.

T cells reacting to self-components can promote tissue damage when escaping tolerogenic control mechanisms which may result in autoimmune disease. The current treatments for these disorders are not antigen (Ag) specific and can compromise host immunity through chronic suppression. We have previously demonstrated that co-administration of encapsulated or free Ag with tolerogenic nanoparticles (tNPs) comprised of biodegradable polymers that encapsulate rapamycin are capable of inhibiting Ag-specific transgenic T cell proliferation and inducing Ag-specific regulatory T cells (Tregs). Here, we further show that tNPs can trigger the expansion of endogenous Tregs specific to a target Ag. The proportion of Ag-specific Treg to total Ag-specific T cells remains constant even after subsequent Ag challenge in combination with a potent TLR7/8 agonist or complete Freund's adjuvant. tNP-treated mice do not develop experimental autoimmune encephalomyelitis (EAE) after adoptive transfer of encephalitogenic T cells; furthermore, tNP treatment provided therapeutic protection in relapsing EAE that was transferred to naïve animals. These findings describe a potent therapy to expand Ag-specific Tregs in vivo and suppress T cell-mediated autoimmunity.

Examining Sense of Community among Hispanic Catholic Parishes by Economic Status, Location-Site, and Family Size.

In the present study, Roman Catholic deacons at one of the 216 Hispanic parishes across the U.S. reported on their parish sense of community (P-SOC), using the SCI-2, within the congregation. P-SOC was assessed among socioeconomic status of lower/working class (n = 109) or middle class (n = 107) Latino parishes, located in either an urban (n = 152) or urban cluster (n = 64) site, with the number of families within the parish to reflect a tiny (n = 76), small (n = 46), moderate (n = 38), or large (n = 54) size. A 2 × 2 × 4 MANOVA on four P-SOC sub-scale scores found no significant main or interaction effect for status, site, or size. It appears per public perception that a sense of connectedness and closeness exists in the Hispanic parishes that are poor, urban, and large congregations is a myth at best.

Male and Female Ministers: Comparing Roman Catholic and Methodist Deacons on Personality Structure, Religious Beliefs, and Leadership Styles.

Christian deacons (50 Roman Catholic; 50 Methodist) self-reported their personality, religiosity, and leadership attributes, plus social desirability tendencies. There were no significant correlates between social desirability and any of these self-reported variables. Results also found no significant differences across Christian denominations on personality dimensions, religious and spirituality beliefs, or leadership styles. Also, there were no significant differences in self-reported personality, religiosity, or leadership among Catholic male deacons with Methodist female deacons only ( n = 43). Taken together, in the present exploratory study across denomination and gender, Christian deacons view themselves similarly in personality, religiosity, and overall leadership characteristics.

Improving the efficacy and safety of biologic drugs with tolerogenic nanoparticles.

The development of antidrug antibodies (ADAs) is a common cause for the failure of biotherapeutic treatments and adverse hypersensitivity reactions. Here we demonstrate that poly(lactic-co-glycolic acid) (PLGA) nanoparticles carrying rapamycin, but not free rapamycin, are capable of inducing durable immunological tolerance to co-administered proteins that is characterized by the induction of tolerogenic dendritic cells, an increase in regulatory T cells, a reduction in B cell activation and germinal centre formation, and the inhibition of antigen-specific hypersensitivity reactions. Intravenous co-administration of tolerogenic nanoparticles with pegylated uricase inhibited the formation of ADAs in mice and non-human primates and normalized serum uric acid levels in uricase-deficient mice. Similarly, the subcutaneous co-administration of nanoparticles with adalimumab resulted in the durable inhibition of ADAs, leading to normalized pharmacokinetics of the anti-TNFα antibody and protection against arthritis in TNFα transgenic mice. Adjunct therapy with tolerogenic nanoparticles represents a novel and broadly applicable approach to prevent the formation of ADAs against biologic therapies.

Substance abuse relapse in Oxford House recovery homes: A survival analysis evaluation.

BACKGROUND: This study used survival analysis to examine risk factors for substance abuse relapse among residents in Oxford Houses (OH), a national network of self-run, self-financed aftercare homes for individuals recovering from substance use disorders. METHODS: Participants who entered OH within 60 days of a 1-year longitudinal study (N = 268) were selected from of a nationally representative US sample. Discrete-time survival analysis compared baseline risk of relapse with 4 hypothesized survival models that included time-invariant and time-varying factors across 3 subsequent time periods. RESULTS: The model predicting higher risk for more severe substance use disorders and psychiatric problems was supported. The hypothesized model that predicted time-varying increases in alcohol (but not drug) abstinence self-efficacy significantly affected risk of relapse. Hypothesized demographic and employment variables did not significantly predict relapse risk. CONCLUSIONS: Results suggested that OH recovery homes may reduce relapse by providing closer monitoring and referring additional services to new residents with more severe prior addiction severity. Risk for relapse may also be reduced by enhancing abstinence self-efficacy for alcohol regardless of drug of choice.

Hope and Abstinence Self-Efficacy: Positive Predictors of Negative Affect in Substance Abuse Recovery.

Goal-oriented thinking, including hope and self-efficacy, might play a constructive and integral role in the substance abuse recovery process, although such an effect may differ by race. The current study investigated hope and self-efficacy, specifically abstinence self-efficacy, as predictors of negative affect (i.e. depression and anxiety) in a longitudinal sample of men and women in substance abuse recovery who lived in sober living homes. We found hope agency and self-efficacy were related but not identical constructs; hope agency and self-efficacy predicted depressive and anxiety symptoms for individuals in recovery, yet these relationships were moderated by race. Theoretical and clinical implications for promoting positive affect among individuals in substance abuse recovery are discussed.

Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance.

Current treatments to control pathological or unwanted immune responses often use broadly immunosuppressive drugs. New approaches to induce antigen-specific immunological tolerance that control both cellular and humoral immune responses are desirable. Here we describe the use of synthetic, biodegradable nanoparticles carrying either protein or peptide antigens and a tolerogenic immunomodulator, rapamycin, to induce durable and antigen-specific immune tolerance, even in the presence of potent Toll-like receptor agonists. Treatment with tolerogenic nanoparticles results in the inhibition of CD4+ and CD8+ T-cell activation, an increase in regulatory cells, durable B-cell tolerance resistant to multiple immunogenic challenges, and the inhibition of antigen-specific hypersensitivity reactions, relapsing experimental autoimmune encephalomyelitis, and antibody responses against coagulation factor VIII in hemophilia A mice, even in animals previously sensitized to antigen. Only encapsulated rapamycin, not the free form, could induce immunological tolerance. Tolerogenic nanoparticle therapy represents a potential novel approach for the treatment of allergies, autoimmune diseases, and prevention of antidrug antibodies against biologic therapies.

RECIPROCAL RESPONSIBILITY AND SOCIAL SUPPORT AMONG WOMEN IN SUBSTANCE USE RECOVERY.

This study sought to identify individual- and house-level predictors of women's employment, education, and retention in self-run recovery homes. Data from a national study of 292 women in Oxford House, an international organization of recovery homes grounded on self-help/mutual aid and 12-step principles were analyzed. Results indicated that the house's Reciprocal Responsibility predicted number of days of paid work. Individual and house variables did not predict participation in education. The presence of recovery home members in personal social networks was statistically significant in predicting retention in the recovery home. Lastly, results indicated that number of days of paid work were not predictive of likelihood of substance use in the next 12 months. The findings of this study indicate that the ability to develop social networks and Reciprocal Responsibility in recovery homes can contribute to positive outcomes for women.

Social anxiety and communal living: The influence of social anxiety on men and women in substance abuse recovery homes.

Research has demonstrated high rates of co-occurrence among anxiety and substance use disorders. However, few studies have specifically examined the relationship between substance use and social anxiety among individuals who are in substance abuse recovery. The present study examined social anxiety as a predictor of substance use among a sample randomized to a sober-living home versus usual aftercare. Given the social nature of many substance abuse treatment and aftercare programs, it was also hypothesized that high levels of social anxiety would reduce the length of stay in the sober-living home and negatively influence participation in self-help groups. Results suggested that social anxiety was a significant predictor of relapse at one time point, and that social anxiety decreased the likelihood for remaining in a sober-living house for six months or more. No significant relationship between social anxiety and participation in self-help groups were found. Implications for further research and substance abuse treatment are discussed.