ABSTRACT
OBJECTIVE: To assess quality of life (QoL) and psychological aspects in patients with gestational trophoblastic disease (GTD). METHODS: This cross-sectional self-report study was conducted among 54 women. Validated question-naires assessed QoL (WHO-QOL-bref), symptoms of depression (Beck Depression Inventory [BDI]) and anxiety (State-Trait Anxiety Inventory [STAI]). RESULTS: Most patients rated overall QoL as good (44.44%) and were satisfied with their health status (42.59%). Mean QoL domain score was lowest for psychologic health (53.86 +/- 21.46) and highest for social relationships (65.74 +/- 22.41). BDI mean was 15.81 +/- 11.15, indicating dysphoria. STAI means were 46 +/- 6.46 for trait-anxiety and 43.72 +/- 4.23 for state-anxiety, both evidencing medium-high anxiety. Among employed patients, environment domain mean was the highest (p = 0.024). Presence of children resulted in lowest means for physical health (p = 0.041) and environment (p= 0.045). Patients desiring children showed significantly higher means for physical health (p = 0.004), psychological health (p = 0.021) and environment (p = 0.003). Chemotherapy had no significant influence on QoL (p > 0.05). CONCLUSION: This study evidenced psychological impact on GTD patients, suggesting specialized care centers should provide psychological interventions during treatment and follow-up of GTD patients, highlighting the importance of a multidisciplinary approach.
Subject(s)
Gestational Trophoblastic Disease/psychology , Quality of Life/psychology , Adolescent , Adult , Anxiety/psychology , Cross-Sectional Studies , Depression/psychology , Female , Gestational Trophoblastic Disease/drug therapy , Health Status , Humans , Hydatidiform Mole/drug therapy , Hydatidiform Mole/psychology , Interpersonal Relations , Marital Status , Pregnancy , Surveys and QuestionnairesABSTRACT
Doença trofoblástica gestacional (DTG) é um grupo de anomalias proliferativas em células trofoblásticas placentárias que levam a diferentes quadros evolutivos: remissão espontânea, invasão miometrial, metástase e recorrência. O medo da doença, da quimioterapia e da recorrência, bem como a incerteza quanto a futuras gestações são fatores de estresse que afetam consideravelmente a qualidade de vida das pacientes com DTG. Todos esses transtornos resultam em estresse psicológico, social e sexual no momento do diagnóstico, ao longo do seguimento e até mesmo após a cura. A fim de aperfeiçoar a assistência, a qualidade de vida tem sido avaliada em pacientes com diferentes doenças. Entretanto, poucos estudos têm como foco a influência da DTG sobre aspectos psicológicos, sociais e sexuais. Este trabalho tem como objetivo a revisão de estudos sobre qualidade de vida e aspectos psicológicos em pacientes com doença trofoblástica gestacional.
