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1.
Arq. bras. endocrinol. metab ; 49(5): 769-775, out. 2005. tab
Article in Portuguese | LILACS | ID: lil-419978

ABSTRACT

INTRODUÇÃO: Determinar prospectivamente a prevalência de lesão adrenal incidental a tomografia computadorizada (TC) em um hospital geral universitário brasileiro. PACIENTES E MÉTODO: Estudo transversal, prospectivo, avaliando pacientes consecutivos sem doença adrenal conhecida, submetidos a TC de tórax e abdome no Hospital de Clínicas de Porto Alegre, em um período de 10 meses. Incidentalomas adrenais foram definidos pela presença de alteração no contorno, tamanho ou densidade da glândula. Valores de kappa foram calculados, avaliando a concordância intra e inter-observador. RESULTADOS: Identificaram-se 101 lesões adrenais incidentais em 83 de 3.382 pacientes, correspondendo a uma prevalência de 2,5 por cento (IC 95 por cento: 1,0 por cento-3,2 por cento). A prevalência de lesões adrenais aumentou com a idade e foi significativamente mais alta em pacientes do sexo masculino (3,3 por cento vs. 1,5 por cento; p= 0,01). Na avaliação das concordâncias intra e inter-observador, obteve-se um kappa de 0,76 (boa concordância) e 0,83 (excelente concordância) respectivamente. CONCLUSÕES: A prevalência de incidentaloma adrenal detectada por TC foi semelhante à de diversas séries clínicas retrospectivas publicadas. Os dois fatores que influenciaram de forma independente a distribuição dos incidentalomas foram aumento na idade e sexo masculino.


Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Middle Aged , Adrenal Gland Neoplasms , Incidental Findings , Age Distribution , Adrenal Gland Neoplasms/epidemiology , Brazil/epidemiology , Cross-Sectional Studies , Hospitals, General , Observer Variation , Prevalence , Prospective Studies , Sex Distribution , Tomography, X-Ray Computed
2.
Arq Bras Endocrinol Metabol ; 49(5): 769-75, 2005 Oct.
Article in Portuguese | MEDLINE | ID: mdl-16444359

ABSTRACT

OBJECTIVE: To prospectively determine the prevalence of incidental adrenal lesions at computed tomography (CT) at an University Hospital in Brazil. PATIENTS AND METHOD: A cross-sectional prospective study was performed to evaluate 3,382 consecutive patients with no known adrenal disease or malignancies who underwent chest and abdominal CT scans over a ten-month period. The cases of adrenal incidentaloma were defined by the presence of any change in gland contour, size or density. Kappa values were calculated, evaluating the intra and inter-observer agreement. RESULTS: One hundred and one incidental adrenal masses were identified, corresponding to 83 cases and a prevalence of 2.5% (CI 95%: 1.0%-3.2%). Male patients presented a higher prevalence of incidentaloma than female (3.3% vs. 1.5%; p= 0.01). There was a significant association between older age and higher frequency of incidentaloma. Kappa of 0.76 and 0.83 (good and excellent agreement, respectively), were obtained in evaluating the intra and inter-observer agreements. CONCLUSIONS: The prevalence of adrenal incidentaloma detected by CT was similar to that of various published retrospective clinical series. The two factors that independently influenced the distribution of incidentalomas were older age and being male.


Subject(s)
Adrenal Gland Neoplasms/diagnostic imaging , Incidental Findings , Adolescent , Adrenal Gland Neoplasms/epidemiology , Adult , Age Distribution , Brazil/epidemiology , Child , Child, Preschool , Cross-Sectional Studies , Female , Hospitals, General , Humans , Infant , Infant, Newborn , Male , Middle Aged , Observer Variation , Prevalence , Prospective Studies , Sex Distribution , Tomography, X-Ray Computed
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