Is Muscle Pain in Temporomandibular Disorder a Hyperactivity Problem? A Clinical, Thermographic, and Electromyographic Analysis.

ABSTRACT: This study aimed to report clinical data on muscle pain in temporomandibular disorders using thermography, algometry, and surface electromyography (EMG). This was done to support or rule out the hypothesis that painful muscles are always related to muscular hyperactivity. This cross-sectional, analytical study included 50 participants who underwent clinical examination and evaluation of anterior temporal muscles and bilateral masseters using thermography, algometry, and EMG. The muscles with greater pain symptoms had hyporadiation and a lower temperature compared with both contralateral muscles and muscles in the asymptomatic group. There was no muscle hyperactivity at rest on EMG analysis; however, there was a greater capacity for muscle recruitment of these symptomatic muscles after a joint decompression test with cotton rolls, suggesting hypoactivity of the affected muscles in the symptomatic patient group. Muscle pain may be related to hypoactivity of the musculature when there is neurological inhibition of the recruitment of muscle fibers, and treatment must consider these neurophysiological alterations. LEVEL OF EVIDENCE: Level IV.

Enhancing microalgae biomass production: Exploring improved scraping frequency in a hybrid cultivation system.

Recently, hybrid systems, such as those incorporating high-rate algal ponds (HRAPs) and biofilm reactors (BRs), have shown promise in treating domestic wastewater while cultivating microalgae. In this context, the objective of the present study was to determine an improved scraping frequency to maximize microalgae biomass productivity in a mix of industrial (fruit-based juice production) and domestic wastewater. The mix was set to balance the carbon/nitrogen ratio. The scraping strategy involved maintaining 1 cm wide stripes to retain an inoculum in the reactor. Three scraping frequencies (2, 4, and 6 days) were evaluated. The findings indicate that a scraping frequency of each 2 days provided the highest biomass productivity (18.75 g total volatile solids m-2 d-1). The species' behavior varied with frequency: Chlorella vulgaris was abundant at 6-day intervals, whereas Tetradesmus obliquus favored shorter intervals. Biomass from more frequent scraping demonstrated a higher lipid content (15.45%). Extrapolymeric substance production was also highest at the 2-day frequency. Concerning wastewater treatment, the system removed 93% of dissolved organic carbon and ∼100% of ammoniacal nitrogen. Combining industrial and domestic wastewater sources to balance the carbon/nitrogen ratio enhanced treatment efficiency and biomass yield. This study highlights the potential of adjusting scraping frequencies in hybrid systems for improved wastewater treatment and microalgae production.

Postnatal Zika virus infection leads to morphological and cellular alterations within the neurogenic niche.

The Zika virus received significant attention in 2016, following a declaration by the World Health Organization of an epidemic in the Americas, in which infections were associated with microcephaly. Indeed, prenatal Zika virus infection is detrimental to fetal neural stem cells and can cause premature cell loss and neurodevelopmental abnormalities in newborn infants, collectively described as congenital Zika syndrome. Contrastingly, much less is known about how neonatal infection affects the development of the newborn nervous system. Here, we investigated the development of the dentate gyrus of wild-type mice following intracranial injection of the virus at birth (postnatal day 0). Through this approach, we found that Zika virus infection affected the development of neurogenic regions within the dentate gyrus and caused reactive gliosis, cell death and a decrease in cell proliferation. Such infection also altered volumetric features of the postnatal dentate gyrus. Thus, we found that Zika virus exposure to newborn mice is detrimental to the subgranular zone of the dentate gyrus. These observations offer insight into the cellular mechanisms that underlie the neurological features of congenital Zika syndrome in children.

Biocompounds from wastewater-grown microalgae: a review of emerging cultivation and harvesting technologies.

Microalgae biomass has attracted attention as a feedstock to produce biofuels, biofertilizers, and pigments. However, the high production cost associated with cultivation and separation stages is a challenge for the microalgae biotechnology application on a large scale. A promising approach to overcome the technical-economic limitations of microalgae production is using wastewater as a nutrient and water source for cultivation. This strategy reduces cultivation costs and contributes to valorizing sanitation resources. Therefore, this article presents a comprehensive literature review on the status of microalgae biomass cultivation in wastewater, focusing on production strategies and the accumulation of valuable compounds such as lipids, carbohydrates, proteins, fatty acids, and pigments. This review also covers emerging techniques for harvesting microalgae biomass cultivated in wastewater, discussing the advantages and limitations of the process, as well as pointing out the main research opportunities. The novelty of the study lies in providing a detailed analysis of state-of-the-art and potential advances in the cultivation and harvesting of microalgae, with a special focus on the use of wastewater and implementing innovative strategies to enhance productivity and the accumulation of compounds. In this context, the work aims to guide future research concerning emerging technologies in the field, emphasizing the importance of innovative approaches in cultivating and harvesting microalgae for advancing knowledge and practical applications in this area.

Congenital Zika Virus Infection Impairs Corpus Callosum Development.

Congenital Zika syndrome (CZS) is a set of birth defects caused by Zika virus (ZIKV) infection during pregnancy. Microcephaly is its main feature, but other brain abnormalities are found in CZS patients, such as ventriculomegaly, brain calcifications, and dysgenesis of the corpus callosum. Many studies have focused on microcephaly, but it remains unknown how ZIKV infection leads to callosal malformation. To tackle this issue, we infected mouse embryos in utero with a Brazilian ZIKV isolate and found that they were born with a reduction in callosal area and density of callosal neurons. ZIKV infection also causes a density reduction in PH3+ cells, intermediate progenitor cells, and SATB2+ neurons. Moreover, axonal tracing revealed that callosal axons are reduced and misrouted. Also, ZIKV-infected cultures show a reduction in callosal axon length. GFAP labeling showed that an in utero infection compromises glial cells responsible for midline axon guidance. In sum, we showed that ZIKV infection impairs critical steps of corpus callosum formation by disrupting not only neurogenesis, but also axon guidance and growth across the midline.

Translation and validity of the Multidimensional Individual and Interpersonal Resilience Measure.

OBJECTIVE: to translate, culturally adapt and validate the Multidimensional Individual and Interpersonal Resilience Measure to Brazilian Portuguese. METHOD: after initial translation, the pre-final version underwent rigorous cultural adaptation procedures. As a result, the final adapted version was submitted to a validity study. RESULTS: adaptation procedures provided equivalence between the pre-final and the original versions in semantic, idiomatic, experiential and conceptual terms. A total of 187 older adults were included in the validity study. Exploratory factorial analysis (EFA) generated a model of five factors ((RMSEA = 0.030; TLI = 0.959; X2 = 151.590 p> 0.05). Final version showed adequate consistency (Cronbach's α = 0.705) and test-retest reliability (ICC=0.835). No statistically significant correlation was found between resilience and sociodemographic and epidemiological variables assessed in this study. CONCLUSION: EMRII-BR is a valid and reliable instrument for measuring resilience in Brazilian older adults.

Orofacial myofunctional therapy associated with the use of the stimulating palatal plate in children with trisomy 21: case studies. / Terapia miofuncional orofacial associada ao uso da placa palatina de memória em crianças com Trissomia do 21: estudo de casos.

Individuals with trisomy 21 may have muscle hypotonia of the speech articulation organs, an enlarged protruding tongue positioned on the floor of the mouth, and a lack of lip closure. The stimulating palatal plate is an intraoral appliance that, associated with myofunctional therapy, aims to improve these children's habitual lip and tongue posture. This study aimed to present the cases of four male children with trisomy 21, with a mean age of 6.7 and a standard deviation of 7.8 months, who used the stimulating palatal plate in association with myofunctional therapy. The children used the plate for 6 months and did exercises based on the orofacial regulation therapy, and their parents received instructions on feeding them and removing deleterious oral habits. In the first session and at the end of the treatment, each child's face was video-recorded for 5 minutes at rest, and two researchers analyzed independently their habitual tongue and lip posture. Participants who began the treatment earlier and had the most severe postural changes had greater tongue and lip posture improvement.

Indivíduos com Trissomia do 21 podem apresentar hipotonia muscular dos órgãos fonoarticulatórios, língua alargada, posicionada no assoalho oral e protrusa e ausência de selamento labial. A placa palatina de memória é um dispositivo intraoral que, associado à terapia miofuncional, visa à melhora da postura habitual dos lábios e da língua dessas crianças. O objetivo deste trabalho foi apresentar os casos de quatro crianças com Trissomia do 21, do sexo masculino, com média de idade de 6,7 e desvio-padrão de 7,8 meses, que fizeram uso da placa palatina de memória de forma associada à terapia miofuncional. As crianças utilizaram a placa por seis meses, realizaram exercícios baseados na terapia de regulação orofacial e receberam orientações quanto à alimentação e retirada de hábitos orais deletérios. Na primeira sessão e ao final do tratamento, foi realizada a gravação de 5 minutos da face de cada criança em repouso e a análise da postura habitual de língua e de lábios foi realizada por dois pesquisadores independentes. Observou-se maior melhora da postura de língua e de lábios dos participantes que iniciaram o tratamento mais precocemente e que apresentavam as alterações posturais mais severas.

Influência da idade e do tempo de uso da Placa Palatina de Memória por crianças com Trissomia do 21 nas mudanças miofuncionais orofaciais percebidas pelos pais, na adaptação e satisfação da família após quatro meses de tratamento / nfluence of age and time of use of the Stimulating Palatal Plate by children with Trisomy 21 on orofacial myofunctional changes perceived by parents, children's adaptation, and family's satisfaction after four months of treatment / Influencia de la edad y el tiempo de uso de la placa de memoria palatina por niños con trisomía 21 sobre los cambios miofuncionales orofaciales percibidos por los padres, adaptación y satisfacción familiar después de cuatro meses de tratamiento

Objetivo: verificar se a idade das crianças com Trissomia do 21 e o tempo de uso por dia da placa palatina de memória influenciam a adaptação da criança à placa, as mudanças miofuncionais orofaciais percebidas pelos pais e a satisfação da família, após quatro meses de tratamento. Métodos: participaram do estudo14 pais ou responsáveis legais de crianças com Trissomia do 21, com idades de 3 a 20 meses. O tratamento com a placa palatina de memória foi realizado durante quatro meses. A adaptação da criança à placa, as mudanças miofuncionais orofaciais percebidas pelos pais e a satisfação das famílias em relação ao tratamento foram investigadas por meio de questionário elaborado pelos autores da pesquisa e respondido pelas mães após quatro meses de tratamento. Resultados: a média de idade das crianças que participaram do estudo foi 10 meses e o desvio-padrão de 4,9 meses. O resultado do questionário indicou associação entre idade e postura de lábios relatada pelos pais com o uso da placa palatina de memória, sendo que todas as crianças menores de 10 meses mantiveram o selamento labial, de acordo com os pais, durante o uso da placa; bem como entre idade e satisfação com o tratamento, sendo que as mães das crianças menores mostraram-se mais satisfeitas. Conclusão: os resultados do estudo indicam que houve associação entre idade e postura de lábios relatada pelos pais com o uso da placa, bem como entre idade e satisfação com o tratamento e sugerem que o tratamento precoce com a placa palatina de memória beneficia as crianças com Trissomia do 21. (AU)

Purpose: to verify if the age of children with Trisomy 21 and the time of use per day of the stimulating palatal plate influence the child's adaptation to the plate, the orofacial myofunctional changes perceived by the parents, and the family's satisfaction, after four months of treatment. Methods: 14 parents or legal guardians of children with Trisomy 21, aged between 3 and 20 months, participated in the study. Treatment with the stimulating palatal plate was carried out for four months. The child's adaptation to the plate, the orofacial myofunctional changes perceived by the parents, and the families' satisfaction with the treatment were investigated through a questionnaire prepared by the research authors and answered by the mothers after four months of treatment. Results: The mean age of the children who participated in the study was 10 months and the standard deviation was 4.9 months. The results of the questionnaire indicated an association between age and lip posture, reported by parents, during the use of the stimulating palatal plate, and all children under 10 months maintained lip closure, according to the parents, during the use of the plate. Age was also associated with satisfaction with the service, as the mothers of younger children were more satisfied. Conclusion: The study results indicate an association between age and lip posture, reported by the parents, during the use of the plate, and between age and satisfaction with the service. Thus, it suggests that early treatment with the stimulating palatal plate benefits children with Trisomy 21. (AU)

Objetivo: verificar si la edad de los niños con Trisomía 21 y el tiempo de uso por día de la placa palatina de memoria influyen en la adaptación del niño a la placa, los cambios miofuncionales orofaciales percibidos por los padres y la satisfacción de la familia, después de cuatro meses de tratamiento. Métodos: Participaron en el estudio 14 padres o tutores legales de niños con trisomía 21, con edades comprendidas entre los 3 y los 20 meses. El tratamiento con la placa de memoria palatina se llevó a cabo durante cuatro meses. La adaptación del niño al plato, los cambios miofuncionales orofaciales percibidos por los padres y la satisfacción de las familias con el tratamiento fueron investigados a través de un cuestionario elaborado por los autores y respondido por las madres, después de cuatro meses de tratamiento. Resultados: La edad media de los niños que participaron en el estudio fue de 10 meses y la desviación estándar fue de 4,9. El resultado del cuestionario indicó una asociación entre la edad y la postura de los labios, reportada por los padres, con el uso de la placa de memoria palatina, y todos los niños menores de 10 meses mantuvieron el sello de los labios, según los padres, durante el uso de la placa de memoria palatina, así como entre la edad y la satisfacción con el servicio. Las madres de niños más pequeños estaban más satisfechas. Conclusión: Los resultados del estudio indican que hubo asociación entre la edad y la postura de los labios, reportada por los padres, con el uso de la placa, así como entre la edad y la satisfacción con el servicio, y sugieren que el tratamiento temprano con la placa de memoria palatina beneficia a los niños con trisomía 21. (AU)

Seasonal changes characterise the shark and ray assemblages in a subtropical shallow sandy habitat in the iSimangaliso Wetland Park, South Africa.

Understanding how environmental drivers influence shark and ray spatial and temporal patterns can provide crucial knowledge for their evidence-based protection and long-term monitoring. However, information on which drivers of variation are most important for elasmobranch communities on soft sediments is limited. Using baited remote underwater stereo-video systems (stereo-BRUVs), we investigated how seasonal and environmental variables affected the elasmobranchs of the iSimangaliso Wetland Park marine protected area (MPA) in South Africa (SA). In total, 11 species were identified from 48 sites between 12 m and 33 m water depth in a sandy habitat. While species richness was similar across seasons, the total abundance of elasmobranchs recorded was higher in winter than summer. The species assemblage composition varied significantly between seasons, with the Human's whaler shark Carcharhinus humani prevalent in summer and the Critically Endangered whitespotted wedgefish Rhynchobatus djiddensis more abundant during winter. Most species were sighted throughout the entire depth range, but rays were more common in shallower waters (< 25 m depth), while C. humani and R. djiddensis were more common in the deeper depth zone of this study. This research provides baseline information about this previously unexplored sandy habitat for elasmobranchs in a site of regional and global significance. Records of species of conservation concern in the sampling area highlight the importance of protecting sand environments within an MPA.

Bridging archaeology and marine conservation in the Neotropics.

Anthropogenic impacts on tropical and subtropical coastal environments are increasing at an alarming rate, compromising ecosystem functions, structures and services. Understanding the scale of marine population decline and diversity loss requires a long-term perspective that incorporates information from a range of sources. The Southern Atlantic Ocean represents a major gap in our understanding of pre-industrial marine species composition. Here we begin to fill this gap by performing an extensive review of the published data on Middle and Late Holocene marine fish remains along the southern coast of Brazil. This region preserves archaeological sites that are unique archives of past socio-ecological systems and pre-European biological diversity. We assessed snapshots of species compositions and relative abundances spanning the last 9500 years, and modelled differences in species' functional traits between archaeological and modern fisheries. We found evidence for both generalist and specialist fishing practices in pre-European times, with large body size and body mass caught regularly over hundreds of years. Comparison with modern catches revealed a significant decline in these functional traits, possibly associated with overfishing and escalating human impacts in recent times.

Gelatin methacryloyl hydrogel as an injectable scaffold with multi-therapeutic effects to promote antimicrobial disinfection and angiogenesis for regenerative endodontics.

Regenerative endodontics represents a paradigm shift in dental pulp therapy for necrotic young permanent teeth. However, there are still challenges associated with attaining maximum root canal disinfection while supporting angiogenesis and preserving resident stem cells viability and differentiation capacity. Here, we developed a hydrogel system by incorporating antibiotic-eluting fiber-based microparticles in gelatin methacryloyl (GelMA) hydrogel to gather antimicrobial and angiogenic properties while prompting minimum cell toxicity. Minocycline (MINO) or clindamycin (CLIN) was introduced into a polymer solution and electrospun into fibers, which were further cryomilled to attain MINO- or CLIN-eluting fibrous microparticles. To obtain hydrogels with multi-therapeutic effects, MINO- or CLIN-eluting microparticles were suspended in GelMA at distinct concentrations. The engineered hydrogels demonstrated antibiotic-dependent swelling and degradability while inhibiting bacterial growth with minimum toxicity in dental-derived stem cells. Notably, compared to MINO, CLIN hydrogels enhanced the formation of capillary-like networks of endothelial cells in vitro and the presence of widespread vascularization with functioning blood vessels in vivo. Our data shed new light onto the clinical potential of antibiotic-eluting gelatin methacryloyl hydrogel as an injectable scaffold with multi-therapeutic effects to promote antimicrobial disinfection and angiogenesis for regenerative endodontics.

Análise da satisfação corporal em mulheres após cirurgia bariátrica e suas alterações psicológicas, comportamentais e alimentares / Analysis of body satisfaction in women after bariatric surgery and its psychological, bahavioral and eating changes / Análisis de la satisfacción corporal en mujeres tras la cirugía bariátrica y sus cambios psicológicos, conductuales y alimentarios

INTRODUÇÃO: A obesidade é uma doença crônica e de causa multifatorial caracterizada pelo acúmulo excessivo de gordura no corpo. A cirurgia bariátrica é um dos procedimentos indicados para o tratamento da obesidade. OBJETIVO: Este estudo teve como objetivo analisar a satisfação física de mulheres submetidas à cirurgia bariátrica, avaliando a incidência de alterações psicológicas pós-operatórias, comportamentos alimentares, escores de autoestima e compulsão alimentar. MÉTODOS: Este projeto foi aprovado pelo Comitê de Ética da Universidade São Judas Tadeu (CAAE 46628521.5.0000.0089). Trata-se de um estudo de caráter quantitativo com delineamento transversal que foi realizado em um grupo de 39 indivíduos do sexo feminino, com idade entre 27 e 56 anos, que se submeteram à cirurgia bariátrica do tipo Bypass Gástrico em Y de Roux há pelo menos 2 anos. Foi utilizado um formulário (Google Forms - http://gg.gg/pesquisacirurgiabariatrica) para a coleta dos dados. RESULTADOS: A análise dos dados evidenciou que as participantes apresentam sobrepeso e insatisfação corporal, mas manifestam autoestima satisfatória. A maioria das participantes afirma experimentar sentimentos positivos ou negativos quando comem, além de não fazer acompanhamento psicológico. CONCLUSÃO: Nota-se a importância do acompanhamento multidisciplinar antes, durante e depois da cirurgia bariátrica para que os resultados sejam duradouros. A terapia cognitivo-comportamental pode ser extremamente eficaz nesse processo, pois atua na modificação de pensamentos e comportamentos disfuncionais diante das necessidades individuais.

INTRODUCTION: Obesity is a chronic, multifactorial disease characterized by the excessive accumulation of fat in the body. Bariatric surgery is one of the procedures indicated for the treatment of obesity. OBJECTIVE: This study aimed to analyze the physical satisfaction of women undergoing bariatric surgery, assessing the incidence of postoperative psychological changes, eating behaviors, self-esteem scores, and binge eating. METHODS: This project was approved by the Ethics Committee of São Judas Tadeu University (CAAE 46628521.5.0000.0089). This is a quantitative cross-sectional study that was carried out on a group of 39 females aged between 27 and 56 who had undergone Roux-en-Y gastric bypass surgery at least two years previously. A form (Google Forms - http://gg.gg/pesquisacirurgiabariatrica) was used to collect the data. RESULTS: Analysis of the data showed that the participants were overweight and had body dissatisfaction but expressed satisfactory self-esteem. Most of the participants said that they experience positive or negative feelings when they eat, and that they do not receive psychological counseling. CONCLUSION: It is important to have multidisciplinary support before, during, and after bariatric surgery so that the results are long-lasting. Cognitive-behavioral therapy can be extremely effective in this process, as it works to modify dysfunctional thoughts and behaviors in the face of individual needs.

INTRODUCCIÓN: La obesidad es una enfermedad crónica y multifactorial caracterizada por la acumulación excesiva de grasa en el organismo. La cirugía bariátrica es uno de los procedimientos indicados para el tratamiento de la obesidad. OBJETIVO: Este estudio tuvo como objetivo analizar la satisfacción física de mujeres sometidas a cirugía bariátrica, evaluando la incidencia de cambios psicológicos postoperatorios, comportamientos alimentarios, puntuaciones de autoestima y atracones. MÉTODOS: Este proyecto fue aprobado por el Comité de Ética de la Universidad São Judas Tadeu (CAAE 46628521.5.0000.0089). Se trata de un estudio cuantitativo, transversal, realizado en un grupo de 39 mujeres con edades comprendidas entre 27 y 56 años que habían sido sometidas a cirugía de bypass gástrico en Y de Roux al menos dos años antes. Para la recogida de datos se utilizó un formulario (Google Forms - http://gg.gg/pesquisacirurgiabariatrica). RESULTADOS: El análisis de los datos mostró que los participantes tenían sobrepeso e insatisfacción corporal, pero expresaron una autoestima satisfactoria. La mayoría de los participantes dijeron que experimentan sentimientos positivos o negativos cuando comen, y que no reciben asesoramiento psicológico. CONCLUSIÓN: Es importante recibir asesoramiento multidisciplinar antes, durante y después de la cirugía bariátrica para que los resultados sean duraderos. La terapia cognitivo-conductual puede ser extremadamente eficaz en este proceso, ya que trabaja para modificar los pensamientos y comportamientos disfuncionales frente a las necesidades individuales.

Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues.

Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-supporting tissues. The limited successful outcomes of clinically available approaches underscore the need for therapeutics that cannot only provide structural guidance to cells but can also modulate the local immune response. Here, three-dimensional melt electrowritten (i.e., poly(ε-caprolactone)) scaffolds with tissue-specific attributes were engineered to guide differentiation of human-derived periodontal ligament stem cells (hPDLSCs) and mediate macrophage polarization. The investigated tissue-specific scaffold attributes comprised fiber morphology (aligned vs. random) and highly-ordered architectures with distinct strand spacings (small 250 µm and large 500 µm). Macrophages exhibited an elongated morphology in aligned and highly-ordered scaffolds, while maintaining their round-shape on randomly-oriented fibrous scaffolds. Expressions of periostin and IL-10 were more pronounced on the aligned and highly-ordered scaffolds. While hPDLSCs on the scaffolds with 500 µm strand spacing show higher expression of osteogenic marker (Runx2) over 21 days, cells on randomly-oriented fibrous scaffolds showed upregulation of M1 markers. In an orthotopic mandibular fenestration defect model, findings revealed that the tissue-specific scaffolds (i.e., aligned fibers for periodontal ligament and highly-ordered 500 µm strand spacing fluorinated calcium phosphate [F/CaP]-coated fibers for bone) could enhance the mimicking of regeneration of natural periodontal tissues.

Small mammals from the Caatinga: A dataset for the Brazilian semiarid biome.

The Caatinga is an exclusively Brazilian biome, and is the largest and most biodiverse Seasonal Tropical Dry Forest in the world. Despite that, the mammalian fauna, especially small mammals, is the least studied of all Brazilian biomes. In order to fill gaps and provide detailed information on small mammals (Didelphimorphia, Rodentia) in the Caatinga biome, we compiled reliable records focusing on richness, composition and some biometric data. These records came from mammal collections, papers, theses, books, and unpublished data, prioritizing records with vouchers housed in scientific collections. We compiled a total of 3133 records from 816 locations, resulting in a richness of 47 native species (12 marsupials and 35 rodents, plus three exotic rodents, Rattus rattus, Rattus norvegicus, and Mus musculus). This dataset includes records of three new species for the biome and its transition zone: the rodents Calomys mattevii, Holochilus oxe, and Nectomys squamipes. Of the total number of records, 1808 (57.71%) are from consulting activities, 95 (3.03%) are from zoonoses studies and 104 (3.32%) are from the National Plague Service (SNP). All nine Brazilian states with territory in the Caatinga have sampling data for small mammals, but the number of records and localities are unevenly distributed, with the state of Rio Grande do Norte having the lowest number of records and locations sampled. Our dataset is the first of its kind for the Caatinga biome and has considerable potential value for studies of habitat use, landscape ecology, macroecology, biogeography, and conservation. There are no copyright restrictions on the data. Please cite this data paper when the data are used in publications. We also request that researchers and teachers inform us of how they are using the data.

Translation and validity of the Multidimensional Individual and Interpersonal Resilience Measure / Tradução e validação do Multidimensional Individual and Interpersonal Resilience Measure / Traducción y validación del Multidimensional Individual and Interpersonal Resilience Measure

ABSTRACT Objective: to translate, culturally adapt and validate the Multidimensional Individual and Interpersonal Resilience Measure to Brazilian Portuguese. Method: after initial translation, the pre-final version underwent rigorous cultural adaptation procedures. As a result, the final adapted version was submitted to a validity study. Results: adaptation procedures provided equivalence between the pre-final and the original versions in semantic, idiomatic, experiential and conceptual terms. A total of 187 older adults were included in the validity study. Exploratory factorial analysis (EFA) generated a model of five factors ((RMSEA = 0.030; TLI = 0.959; X2 = 151.590 p> 0.05). Final version showed adequate consistency (Cronbach's α = 0.705) and test-retest reliability (ICC=0.835). No statistically significant correlation was found between resilience and sociodemographic and epidemiological variables assessed in this study. Conclusion: EMRII-BR is a valid and reliable instrument for measuring resilience in Brazilian older adults.

RESUMO Objetivo: traduzir, adaptar culturalmente e validar o Multidimensional Individual and Interpersonal Resilience Measure para o português brasileiro. Método: após a tradução inicial, a versão pré-final passou por rigorosos procedimentos de adaptação cultural. Como resultado, a versão final adaptada foi submetida a um estudo de validade. Resultados: os procedimentos de adaptação proporcionaram equivalência entre as versões pré-final e original em termos semânticos, idiomáticos, experienciais e conceituais. Um total de 187 idosos foram incluídos no estudo de validade. A análise fatorial exploratória (AFE) gerou um modelo de cinco fatores ((RMSEA = 0,030; TLI = 0,959; X2 = 151,590 p> 0,05). A versão final apresentou consistência adequada (α de Cronbach = 0,705) e confiabilidade teste-reteste (ICC=0,835). Não foi encontrada correlação estatisticamente significativa entre a resiliência e as variáveis sociodemográficas e epidemiológicas avaliadas neste estudo. Conclusão: o EMRII-BR é um instrumento válido e confiável para mensurar a resiliência em idosos brasileiros.

RESUMEN Objetivo: traducir, adaptar culturalmente y validar el Multidimensional Individual and Interpersonal Resilience Measure para el portugués brasileño. Método: después de la traducción inicial, la versión pre-final pasó por rigurosos procedimientos de adaptación cultural. Como resultado, la versión final adaptada fue sometida a un estudio de validez. Resultados: los procedimientos de adaptación proporcionaron equivalencia entre las versiones pre-final y original en términos semánticos, idiomáticos, experienciales y conceptuales. Un total de 187 ancianos fueron incluidos en el estudio de validez. El análisis factorial exploratorio (AFE) generó un modelo de cinco factores ((RMSEA = 0,030; TLI = 0,959; X2 = 151,590 p> 0,05). La versión final mostró adecuada consistencia (α de Cronbach = 0,705) y confiabilidad prueba-reprueba (ICC=0,835). No se encontró correlación estadísticamente significativa entre la resiliencia y las variables sociodemográficas y epidemiológicas evaluadas en este estudio. Conclusión: EMRII-BR es un instrumento válido y confiable para medir la resiliencia en ancianos brasileños.

Distúrbios alimentares e seus fatores genéticos: revisão de literatura / Eating disorders and their genetic factors: literature review / Trastornos alimentarios y sus factores genéticos: revisión de la literatura

Diversas condições psiquiátricas apresentam influência de fatores genéticos, e dentre essas condições encontram-se os distúrbios alimentares: anorexia nervosa, bulimia nervosa e transtorno de compulsão alimentar. Os distúrbios previamente citados apresentam influência genética ligadas à hereditariedade, sendo que cada um deles apresenta características distintas quanto às suas manifestações clínicas, tratamento e diagnóstico. A importância da investigação deste tema e seu objetivo relaciona-se com o propósito de contribuir para elucidar quanto às características gerais dos principais distúrbios alimentares e seus fatores genéticos através da: etiologia, sinais e sintomas, diagnóstico e tratamento e que venha a possibilitar, futuramente, novos estudos com resultados para novas medidas terapêuticas. Como base da pesquisa, foi levantada a seguinte problemática: "Quais as características gerais dos principais distúrbios psiquiátricos, etiologia, sinais e sintomas, diagnóstico e tratamento?". Portanto, realizou- se uma uma busca ativa através dos descritores: "transtorno de compulsão alimentar"; "distúrbios alimentares"; "bulimia nervosa" e "anorexia nervosa", adquiriu-se material pelas fontes: SciELO, ELSEVIER, GOOGLE ACADÊMICO, PUBMED, MEDSCAPE e pelo periódico Arquivos e Ciências da Saúde da UNIPAR. Com isso, foi adquirido material suficiente para concluir a influência genética perante tais distúrbios, além de elucidar suas principais características, tendo assim caráter educativo e científico.

Several psychiatric conditions have genetic factors influence, and among these conditions are eating disorders: anorexia nervosa, bulimia nervosa and binge eating disorder. The previously mentioned disorders have a genetic influence linked to heredity, each one of them having different characteristics as to their clinical manifestations, treatment and diagnosis. The importance of research on this topic and its objective is related to the purpose of contributing to elucidate the general characteristics of the main eating disorders and their genetic factors through: etiology, signs and symptoms, diagnosis and treatment and that will make possible, in the future, new studies with results for new therapeutic measures. As a basis for the research, the following issue was raised: "What are the general characteristics of the main psychiatric disorders, etiology, signs and symptoms, diagnosis and treatment?". Therefore, an active search was carried out through the descriptors: "binge eating disorder"; "eating disorders"; " nervous bulimia" and " nervous anorexia", material was acquired by the sources: SciELO, ELSEVIER, GOOGLE ACADEMIC, PUBMED, MEDSCAPE and by UNIPAR's Archives and Health Sciences. With this, sufficient material was acquired to conclude the genetic influence in the face of such disturbances, besides elucidating its main characteristics, thus having an educational and scientific character.

Varios trastornos psiquiátricos tienen factores genéticos que influyen, y entre estos trastornos se encuentran los trastornos de la alimentación: anorexia nerviosa, bulimia nerviosa y trastorno por atracón. Los trastornos mencionados tienen una influencia genética vinculada a la herencia, cada uno de ellos con características diferentes en cuanto a sus manifestaciones clínicas, tratamiento y diagnóstico. La importancia de la investigación sobre este tema y su objetivo se relaciona con el propósito de contribuir a dilucidar las características generales de los principales trastornos de la conducta alimentaria y sus factores genéticos a través de: etiología, signos y síntomas, diagnóstico y tratamiento y que posibilitarán, en el futuro, nuevos estudios con resultados para nuevas medidas terapéuticas. Como base para la investigación se planteó la siguiente cuestión: "¿Cuáles son las características generales de los principales trastornos psiquiátricos, etiología, signos y síntomas, diagnóstico y tratamiento?". Por lo anterior, se realizó una búsqueda activa a través de los descriptores: "trastorno por atracón"; "trastornos de la conducta alimentaria"; "bulimia nerviosa" y "anorexia nerviosa", material adquirido por las fuentes: SciELO, ELSEVIER, GOOGLE ACADEMIC, PUBMED, MEDSCAPE y por Archivos y Ciencias de la Salud de UNIPAR. Con ello, se adquirió material suficiente para concluir la influencia genética ante tales alteraciones, además de dilucidar sus principales características, teniendo así un carácter educativo y científico.

Terapia miofuncional orofacial associada ao uso da placa palatina de memória em crianças com Trissomia do 21: estudo de casos / Orofacial myofunctional therapy associated with the use of the stimulating palatal plate in children with trisomy 21: case studies

RESUMO Indivíduos com Trissomia do 21 podem apresentar hipotonia muscular dos órgãos fonoarticulatórios, língua alargada, posicionada no assoalho oral e protrusa e ausência de selamento labial. A placa palatina de memória é um dispositivo intraoral que, associado à terapia miofuncional, visa à melhora da postura habitual dos lábios e da língua dessas crianças. O objetivo deste trabalho foi apresentar os casos de quatro crianças com Trissomia do 21, do sexo masculino, com média de idade de 6,7 e desvio-padrão de 7,8 meses, que fizeram uso da placa palatina de memória de forma associada à terapia miofuncional. As crianças utilizaram a placa por seis meses, realizaram exercícios baseados na terapia de regulação orofacial e receberam orientações quanto à alimentação e retirada de hábitos orais deletérios. Na primeira sessão e ao final do tratamento, foi realizada a gravação de 5 minutos da face de cada criança em repouso e a análise da postura habitual de língua e de lábios foi realizada por dois pesquisadores independentes. Observou-se maior melhora da postura de língua e de lábios dos participantes que iniciaram o tratamento mais precocemente e que apresentavam as alterações posturais mais severas.

ABSTRACT Individuals with trisomy 21 may have muscle hypotonia of the speech articulation organs, an enlarged protruding tongue positioned on the floor of the mouth, and a lack of lip closure. The stimulating palatal plate is an intraoral appliance that, associated with myofunctional therapy, aims to improve these children's habitual lip and tongue posture. This study aimed to present the cases of four male children with trisomy 21, with a mean age of 6.7 and a standard deviation of 7.8 months, who used the stimulating palatal plate in association with myofunctional therapy. The children used the plate for 6 months and did exercises based on the orofacial regulation therapy, and their parents received instructions on feeding them and removing deleterious oral habits. In the first session and at the end of the treatment, each child's face was video-recorded for 5 minutes at rest, and two researchers analyzed independently their habitual tongue and lip posture. Participants who began the treatment earlier and had the most severe postural changes had greater tongue and lip posture improvement.

Planejamento e gestão municipal do financiamento do Sistema Único de Saúde: estudo de caso em uma região de saúde catarinense / Municipal planning and management of the Unified Health System financing: a case study in a health region of Santa Catarina, Brazil / Planificación y gestión municipal de la financiación del Sistema Único de Salud: estudio de caso en una región de salud catarinense

O objetivo deste artigo é compreender a percepção dos gestores municipais de saúde sobre as condições de financiamento do Sistema Único de Saúde na região oeste catarinense. Trata-se de um estudo de caso quanti-qualitativo, descritivo. Participaram gestores municipais de saúde que integravam a Comissão Intergestores Regional. A coleta de dados ocorreu por entrevista semiestruturada e com dados do Sistema de Informação de Orçamento Público em Saúde. As entrevistas foram analisadas pelo método do Discurso do Sujeito Coletivo, que resultou em duas ideias centrais: transferências intergovernamentais e planejamento e gestão de recursos municipais de saúde. Evidenciam-se as competências e esforços dos gestores municipais frente ao financiamento do Sistema Único de Saúde, as dificuldades de cooperação regional, o excesso de condicionalidades para uso dos recursos, indicando a necessidade de revisão dos instrumentos indutores da política de saúde, a necessidade de maior comprometimento financeiro do Governo Federal, e o fortalecimento de instâncias com atuação potencializadora de coordenação e cooperação dos entes federados na operacionalização das políticas. Nota-se a falta de espaço fiscal para aplicação de recursos que contribuam para a retomada da atividade econômica e uma nova agenda de financiamento. As principais dificuldades estão relacionadas ao excesso de condicionalidades e à desconsideração das necessidades da região no empenho de recursos públicos.

This study sought to understand the perception of municipal health managers on Unified Health System financing in western Santa Catarina, Brazil. A quantitative and qualitative descriptive case study was conducted with municipal health managers who made up the Regional Interagency Committee. Data were collected by semi-structured interviews and from the Public Health Budget Information System. The interviews were analyzed using the Discourse of the Collective Subject, which resulted in two central ideas: intergovernmental transfers and municipal health resources planning and management. Results highlight municipal managers' skills and efforts regarding Unified Health System funding, the difficulties of regional cooperation, and the excessive conditions for the use of resources. This points to the need to review health policy instruments, the need for greater financial commitment by the federal government, and strengthening bodies that may enhance coordination and cooperation between states in operationalizing policies. There is a lack of fiscal space for resource application that contributes to the resumption of economic activity and a new funding agenda. The main difficulties are related to excessive conditions and the disregard towards the needs of the region regarding public resources allocation.

El objetivo de este estudio es comprender la percepción de los gestores municipales de salud sobre las condiciones de financiación del Sistema Único de Salud (SUS) en la región oeste de Santa Catarina (Brasil). Se trata de un estudio de caso descriptivo cuantitativo y cualitativo. Participaron los gestores municipales de salud que formaron parte de la Comisión Interinstitucional Regional. La recolección de datos ocurrió por entrevistas semiestructuradas y con datos del Sistema de Información del Presupuesto de Salud Pública. Para el análisis de las entrevistas se utilizó el método del Discurso del Sujeto Colectivo, lo que resultó en dos ideas centrales: las transferencias intergubernamentales y la planificación y gestión de los recursos sanitarios municipales. Se evidencian las habilidades y esfuerzos de los gestores municipales con relación al financiamiento del SUS, las dificultades de la cooperación regional, el exceso de condicionalidades para el uso de los recursos, lo que indica la necesidad de revisar los instrumentos que inducen la política de salud, la necesidad de mayor compromiso financiero del gobierno federal, y el fortalecimiento de instancias con acción potenciadora de coordinación y cooperación de las entidades federativas en la puesta en operación de las políticas. Falta espacio fiscal para aplicar los recursos que contribuyan a la reanudación de la actividad económica y una nueva agenda de financiamiento. Las principales dificultades están relacionadas con el exceso de condicionalidades y el desconocimiento de las necesidades de la región en el compromiso de los recursos públicos.

Dialysis-related constrictive pericarditis: old enemies may sometimes come back / Pericardite Constritiva relacionada a diálise: velhos inimigos podem, às vezes, voltar

ABSTRACT Cardiovascular disease is the main cause of death in patients with chronic kidney disease (CKD). Several heart conditions have been associated with CKD, including myocardial and pericardial diseases. This paper describes a case of Dialysis-related constrictive pericarditis in a patient diagnosed with sudden hypotension during a hemodialysis session. A 65-year-old man diagnosed with hypertension, diabetes, obesity, and cirrhosis on hemodialysis for two years complained of symptoms during one of his sessions described as malaise, lipothymia, and confusion. The patient had a record of poor compliance with the prescribed diet and missed dialysis sessions. He was sluggish during the physical examination, and presented hypophonetic heart sounds, a blood pressure of 50/30mmHg, and a prolonged capillary refill time. The patient was referred to the intensive care unit and was started on antibiotics and vasoactive drugs. His workup did not show signs of infection, while electrocardiography showed low QRS-wave voltage. His echocardiogram showed signs consistent with a thickened pericardium without pericardial effusion. Cardiac catheterization showed equalization of diastolic pressures in all heart chambers indicative of constrictive pericarditis. The patient underwent a pericardiectomy. Examination of surgical specimens indicated he had marked fibrosis and areas of dystrophic calcification without evidence of infection, consistent with Dialysis-related constrictive pericarditis. Hypotension for unknown causes must be considered in the differential diagnosis of dialysis patients.

RESUMO A doença cardiovascular é a principal causa de morte em pacientes com doença renal crônica (DRC). Várias formas de acometimento cardíaco têm sido associadas. à DRC, incluindo doenças miocárdicas e pericárdicas. Este artigo descreve um caso de pericardite constritiva relacionada a em um paciente diagnosticado com hipotensão súbita durante uma sessão de hemodiálise. Um homem de 65 anos com diagnósticos prévios de hipertensão, diabetes, obesidade e cirrose em hemodiálise por dois anos queixou-se de sintomas durante uma de suas sessões, descritos como mal-estar, lipotímia e confusão mental. Apresentava histórico de baixa adesão à dieta prescrita e faltas frequentes às sessões de diálise. Ele estava fraco durante o exame físico e apresentava bulhas cardíacas hipofonéticas, pressão arterial de 50/30mmHg e tempo de enchimento capilar prolongado. O paciente foi encaminhado para a unidade de terapia intensiva e iniciou o tratamento com antibióticos e drogas vasoativas. Investigação laboratorial não mostrou sinais de infecção, enquanto o eletrocardiograma mostrou baixa voltagem de complexo QRS. Seu ecocardiograma evidenciou sinais consistentes com um pericárdio espessado, sem derrame pericárdico. O cateterismo cardíaco mostrou equalização das pressões diastólicas em todas as câmaras cardíacas, indicativo de pericardite constritiva. O paciente foi submetido a uma pericardiectomia. O exame anatomopatológico mostrou sinais de acentuada fibrose acentuada fibrose e áreas de calcificação distrófica sem evidência de infecção, consistente com pericardite constritiva relacionada a por diálise. A hipotensão por causas desconhecidas deve ser considerada no diagnóstico diferencial de pacientes em diálise.

Evaluation of the Effects of Exogenous Melatonin in Zygomatic Complex Fractures.

Objective: The objective of this research was to evaluate the benefits of using exogenous melatonin in the preoperative period of patients with zygomatic complex fractures. Materials and methods: A randomized, triple-blind clinical trial of independent samples was carried out. The sample was divided into two groups: G1 (melatonin) and G2 (placebo). Interventions were standardized with 10 mg melatonin or placebo the night before surgery and 1 h before the start of surgery. The studied variables were level of salivary cortisol, level of anxiety, pain, and use of rescue analgesics. Descriptive and inferential statistical analysis was performed, with a margin of error considered as 5%. Results: A total of 14 patients were included, and after using the medication, the measurement of cortisol was reduced in the melatonin group (0.48 ± 0.25 to 0.43 ± 0.13 µg/100 ml) and increased in the placebo group (0.19 ± 0.12 to 0.23 ± 0.18 µg/100 ml). There was a reduction in the level of anxiety in the melatonin group and an increase in the placebo group. After two hours of surgery, the pain was statistically less in the melatonin group (4.50 ± 1.38) compared to the placebo group (6.17 ± 0.98). Six hours after surgery, pain showed regression in both groups. Patients in the placebo group (83.3%) used more rescue analgesics than melatonin group (33.3%) in the postoperative period. Conclusions: Thus, this research demonstrated that melatonin can be effective in reducing salivary cortisol and anxiety after medication, and patients in the melatonin group needed less rescue analgesics in the postoperative period.