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1.
Eat Behav ; 52: 101841, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38154321

ABSTRACT

INTRODUCTION: The prevalence of food addiction among patients seeking bariatric surgery is approximately 30 %. While hyper-palatable foods (HPF) have been identified as the potential 'substance' in food addiction and a contributor to severe obesity, consumption of HPF among individuals with food addiction, including those seeking bariatric surgery, is unknown. Thus, the aim of this study was to evaluate the consumption of HPF among individuals seeking bariatric surgery with food addiction, compared to those without food addiction. METHODS: Participants were N = 54 individuals with severe obesity seeking bariatric surgery. The Yale Food Addiction Scale was used to identify individuals with food addiction (FA) (37 % of sample). Dietary recalls were used to quantify HPF intake. Analyses were conducted to characterize average HPF intake and to determine whether there were significant differences between HPF intake among those with FA compared to those without FA, and whether HFP intake was correlated with FA symptoms. RESULTS: On average, 71 % of participants' daily calorie intake was from HPF. There were no significant differences in HPF items intake among individuals with and without FA (70.46 % vs 71.34; p = 0.85). A positive correlation between number of FA symptoms and the intake of HPF high in fat and sugar ([0.3]; p = 0.03) was observed. CONCLUSION: In this pilot study, HPF consumption among individuals with and without FA seeking bariatric surgery was high overall, however there were no differences across groups. In addition, intake of HPF with fat and sugar was associated with the number of symptoms of food addiction. More studies with a larger sample are needed to confirm these preliminary findings.


Subject(s)
Bariatric Surgery , Food Addiction , Obesity, Morbid , Humans , Food Addiction/epidemiology , Obesity, Morbid/epidemiology , Obesity, Morbid/surgery , Obesity, Morbid/complications , Prevalence , Pilot Projects , Obesity , Sugars , Eating
2.
Cancers (Basel) ; 15(17)2023 Sep 03.
Article in English | MEDLINE | ID: mdl-37686683

ABSTRACT

Cancer is a leading cause of death, and the fibrinolytic system shows cooperative effects that facilitate the growth of tumors and the appearance of metastases. This prospective study aimed to evaluate the fibrinolytic potential in cancer patients and its association with mortality outcomes using the fluorometric method of simultaneous thrombin and plasmin generation. The study included 323 cancer patients and 148 healthy individuals. During the 12-month follow-up, 68 patients died. Compared to the control group, cancer patients showed alterations in thrombin production consistent with a hypercoagulability profile, and an increase in plasmin generation. Mortality risk was associated with two parameters of thrombin in both univariate and multivariable analysis: maximum amplitude (Wald 11.78, p < 0.001) and area under the curve (Wald 8.0, p < 0.005), while such associations were not observed for plasmin. In conclusion, this was the first study able to demonstrate the simultaneous evaluation of thrombin and plasmin generation in newly diagnosed untreated cancer patients. Patients with cancer have been observed to exhibit a hypercoagulable profile. During the study, two parameters linked to thrombin generation, MA and AUC, were identified and found to have a potential association with mortality risk. However, no associations were found with parameters related to plasmin generation.

3.
Quad. psicol. (Bellaterra, Internet) ; 25(3): e1993, 2023. tab
Article in Portuguese | IBECS | ID: ibc-228453

ABSTRACT

Este estudo objetivou identificar crenças de mulheres em situação de violência por parceiros íntimos (VPI) relativas a esta violência e a papéis/estereótipos de gênero. Participaram trinta mulheres, que buscaram uma instituição pública de assistência e proteção à violência. Utilizou-se um roteiro semiestruturado e um questionário sociodemográfico. As entrevistas foram submetidas à Análise de Conteúdo. Os resultados apresentam-se em duas dimensões: “Crenças em relação à VPI” e “Crenças em relação a papéis de gênero”. Verifica-se que o modelo de estrutura sexista da sociedade, garante a reprodução da desigualdade de gênero e mantém ativa uma ideologia fundada nos estereótipos da força e poder masculino versus a submissão e docilidade feminina, em que a violência se faz instrumento (legitimado) estrutural e estruturante. (AU)


This study aimed to identify beliefs of women in situations of intimate partner violence (IPV) regarding this violence and gender roles/stereotypes. Thirty women participated, who sought a public institution of assistance and protection against violence. A semi-structured script and a sociodemographic questionnaire were used. The interviews were submitted to Content Analysis. The results are presented in two dimensions: “Beliefs in relation to IPV” and “Beliefs in relation to gender roles”. It is verified that the sexist structure model of society guarantees the reproduction of gender inequality and keeps active an ideology founded on stereotypes of male strength and power versus female submission and docility, in which violence becomes a (legitimate) structural and structuring instrument. (AU)


Subject(s)
Humans , Female , Intimate Partner Violence , Culture , Gender Stereotyping , Sexism , Domestic Violence , Violence Against Women , Gender-Based Violence
4.
Rev. bras. entomol ; 67(3): e20230047, 2023. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1521738

ABSTRACT

ABSTRACT Aedes (Stegomyia) aegypti is an important vector of dengue, yellow fever, chikungunya and Zika virus. It is well known that resistance monitoring and genetic diversity data help designing the vector control programs. This study aimed to evaluate resistance to pyrethroids (PYs) through the frequency of kdr mutations Val1016IIe and F1534C, and the genetic variation of the mitochondrial gene ND4 in six natural populations of A. aegypti from Paraná - Brazil. Adults were obtained from eggs collected from Alvorada do Sul, Marilena, Maringá, Nova Londrina, Paranavaí and São Carlos do Ivaí. From these adults, 345 were used to identify the 1016 and 1534 sites, and 120 were used to perform the ND4 gene analysis. The studied populations from Paraná showed PYs resistance, low gene flow and genetic diversity. Additionally, a relationship was observed among the haplotypes of populations from the Amazon and Southeastern Brazil, Peru, Mexico, and North America.

5.
Article in Portuguese | LILACS | ID: biblio-1425704

ABSTRACT

A Teoria do Sexismo Ambivalente (SA) propõe uma ambivalência nas manifestações sexistas em relação às mulheres, envolvendo tanto crenças e atitudes abertamente discriminatórias, quanto uma visão de cunho protecionista, idealizador e afetivo. Alguns autores, sobretudo de áreas sociais e de saúde, associam os postulados desta teoria ao fenômeno da violência por parceiros íntimos (VPI). Sendo assim, esta pesquisa consiste em uma revisão sistemática da literatura com objetivo de identificar as relações estabelecidas, em artigos científicos, entre o SA e a VPI. A busca foi realizada nas bases de dados da Biblioteca Virtual em Saúde (BVS), PsycInfo, PubMed, SciELO e Web of Science. Foram selecionados 29 artigos para compor o trabalho. Os resultados apontaram as mulheres como principais vítimas da VPI e mostraram que o sexismo ambivalente pode ter influências significativas neste contexto, podendo atuar como uma maneira de legitimar e sustentar as desigualdades de gênero.


Subject(s)
Marriage , Domestic Violence , Sexism
6.
ACM arq. catarin. med ; 49(3): 111-124, 06/10/2020.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1354321

ABSTRACT

Introdução: O alojamento conjunto é definido como um espaço onde mãe e o recém-nascido saudáveis permanecem juntos após o nascimento até a alta hospitalar. Durante a sua internação, os profissionais de saúde são de extrema importância para uma assistência adequada e humanizada. Objetivo: Identificar quais profissionais e intervenções multiprofissionais são realizadas em recém-nascidos de baixo risco internados no alojamento conjunto. Procedimentos Métodológicos: Revisão sistemática integrativa da literatura com protocolo registrado na PROSPERO (ID134707). A busca foi realizada entre maio de 2018 a outubro de 2019, nas bases de dados MEDLINE, Pubmed, LILACS, SCIELO, PEDro, Scopus, Cochrane, Embase e Cinahl. Foram utilizados os termos medical subject heading (MeSH) Infant, Newborn, "Mother-childrelations", Hospital, Maternity, "Health CareLevels", "Rooming-in Care", e "Physical Therapy Modalities", nos idiomas inglês, português e espanhol. Para avaliação da qualidade utilizou-se Newcastle ­ ottawa quality assessment scale case control studies. Texto da Pesquisa: Somente dois estudos atenderam aos critérios de elegibilidade, demonstrando que os profissionais enfermeiros, fonoaudiólogos e médicos atuam no alojamento conjunto. Uma intervenção foi relacionada ao aleitamento materno, com a avaliação do posicionamento, pega, sucção, aspecto da mama e interação mãe-bebê, e a outra sobre o contato pele a pele e berço aquecido no controle da temperatura corporal do recém-nascido logo após o nascimento. Conclusão: Em razão da escassez de estudos, tornam-se necessárias mais pesquisas com boa qualidade metodológica sobre a atuação de outros profissionais na população de recém-nascidos de baixo risco internados no alojamento conjunto.


Introduction: Maternity is defined as a space where a healthy mother and newborn remain together after birth until hospital discharge. During hospitalization, health professionals are extremely important for adequate and humanized care. Aims: To identify which professionals and multiprofessional interventions are carried out on low-risk newborns admitted to the maternity. Methodological Procedures: Systematic integrative literature review with a protocol registered with PROSPERO (ID134707). The search was conducted between May 2018 - October 2019, in the databases MEDLINE, Pubmed, LILACS, SCIELO, PEDro, Scopus, Cochrane, Embase and Cinahl. The terms medical subject heading (MeSH) Infant, Newborn, "Mother-childrelations", Hospital, Maternity, "Health Care Levels", "Rooming-in Care", and "Physical Therapy Modalities" were used in English, Portuguese and Spanish. The Newcastle - ottawa quality assessment scale case control studies was used to assess quality. Research Text: Only two studies met the eligibility criteria, demonstrating that professional nurses, speech therapists and doctors work in the maternity. One intervention was related to breastfeeding, with the assessment of positioning, holding, sucking, breast aspect and mother-baby interaction, and the other on skin-to-skin contact and a heated cradle to control the newborn's body temperature soon after the birth. Conclusion: Due to the scarcity of studies, more research with good methodological quality on the performance of other professionals in the population of low-risk newborns admitted to the maternity is necessary.

7.
Cad Saude Publica ; 36(6): e00115320, 2020.
Article in English, Portuguese | MEDLINE | ID: mdl-32578805

ABSTRACT

This study aims to analyze the pressure on the Brazilian health system from the additional demand created by COVID-19. The authors performed a series of simulations to estimate the demand for hospital beds (health micro-regions) as well as to ICU beds, and mechanical ventilators (health macro-regions) under different scenarios of intensity (infection rates equivalent to 0.01, 0.1, and 1 case por 100 inhabitants) and time horizons (1, 3, and 6 months). The results reveal a critical situation in the system for meeting this potential demand, with numerous health micro-regions and macro-regions operating beyond their capacity, compromising the care for patients, especially those with more severe symptoms. The study presents three relevant messages. First, it is necessary to slow the spread of COVID-19 in the Brazilian population, allowing more time for the reorganization of the supply and relieve the pressure on the health system. Second, the expansion of the number of available beds will be the key. Even if the private sector helps offset the deficit, the combined supply from the two sectors (public and private) would be insufficient in various macro-regions. The construction of field hospitals is important, both in places with a history of "hospital deserts" and in those already pressured by demand. The third message involves the regionalized organization of health services, whose design may be adequate in situations of routine demand, but which suffer additional challenges during pandemics, especially if patients have to travel long distances to receive care.


O objetivo deste estudo é analisar a pressão sobre o sistema de saúde no Brasil decorrente da demanda adicional gerada pela COVID-19. Para tanto, foi realizado um conjunto de simulações para estimar a demanda de leitos gerais (microrregiões de saúde), leitos de UTI e equipamentos de ventilação assistida (macrorregiões de saúde) em diferentes cenários, para intensidade (taxas de infecção equivalentes a 0,01, 0,1 e 1 caso por 100 habitantes) e horizontes temporais (1, 3 e 6 meses). Os resultados evidenciam uma situação crítica do sistema para atender essa demanda potencial, uma vez que diversas microrregiões e macrorregiões de saúde operariam além de sua capacidade, comprometendo o atendimento a pacientes principalmente aqueles com sintomas mais severos. O estudo apresenta três mensagens relevantes. Em primeiro lugar, é necessário reduzir a velocidade de propagação da COVID-19 na população brasileira, permitindo um tempo maior para a reorganização da oferta e aliviando a pressão sobre o sistema de saúde. Segundo, é necessário expandir o número de leitos disponíveis. Ainda que o setor privado contribua para amortecer o déficit de demanda, a oferta conjunta dos dois setores não seria suficiente em várias macrorregiões. A construção de hospitais de campanha é importante, tanto em locais onde historicamente há vazios assistenciais como também naqueles onde já se observa uma pressão do lado da demanda. A terceira mensagem diz respeito à organização regionalizada dos serviços de saúde que, apesar de adequada em situações de demanda usual, em momentos de pandemia este desenho implica desafios adicionais, especialmente se a distância que o paciente tiver de percorrer for muito grande.


El objetivo de este estudio es analizar la presión sobre el sistema de salud brasileño, ocasionada por la demanda adicional de camas hospitalarias y equipos de ventilación mecánica, generada por el COVID-19. Para tal fin, se realizó un conjunto de simulaciones, con el fin de estimar la demanda de camas generales (microrregiones de salud), camas de UTI y equipamientos de ventilación asistida (macrorregiones de salud) en diferentes escenarios, según la intensidad (tasas de infección equivalentes a 0,01, 0,1 y 1 caso por 100 habitantes) y horizontes temporales (1, 3 y 6 meses). Los resultados evidencian una situación crítica del sistema para atender esa demanda potencial, ya que diversas microrregiones y macrorregiones de salud operarían más allá de su capacidad, comprometiendo la atención a pacientes principalmente aquellos con los síntomas más graves. El estudio presenta tres mensajes relevantes. En primer lugar, es necesario reducir la velocidad de propagación del COVID-19 en la población brasileña, permitiendo un tiempo mayor para la reorganización de la oferta y aliviando la presión sobre el sistema de salud. En segundo lugar, es necesario expandir el número de camas disponibles. A pesar de que el sector privado contribuya a amortiguar el déficit de demanda, la oferta conjunta de los dos sectores no sería suficiente en varias macrorregiones. La construcción de hospitales de campaña es importante, tanto en lugares donde históricamente existen lagunas asistenciales, como también en aquellos donde ya se observa una presión por parte de la demanda. El tercer mensaje se refiere a la organización por regiones de los servicios de salud que, a pesar de ser adecuada en situaciones de demanda habitual, en momentos de pandemia, este diseño implica desafíos adicionales, especialmente si la distancia que el paciente tuviera que recorrer fuera muy lejana.


Subject(s)
Betacoronavirus , Coronavirus Infections/epidemiology , Health Services Needs and Demand/statistics & numerical data , Hospital Bed Capacity/statistics & numerical data , Intensive Care Units/supply & distribution , Pneumonia, Viral/epidemiology , Ventilators, Mechanical/supply & distribution , Brazil/epidemiology , COVID-19 , Coronavirus Infections/prevention & control , Humans , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Private Sector/statistics & numerical data , Public Sector/statistics & numerical data , SARS-CoV-2
8.
Cad. Saúde Pública (Online) ; 36(6): e00115320, 2020. graf
Article in Portuguese | LILACS | ID: biblio-1100969

ABSTRACT

O objetivo deste estudo é analisar a pressão sobre o sistema de saúde no Brasil decorrente da demanda adicional gerada pela COVID-19. Para tanto, foi realizado um conjunto de simulações para estimar a demanda de leitos gerais (microrregiões de saúde), leitos de UTI e equipamentos de ventilação assistida (macrorregiões de saúde) em diferentes cenários, para intensidade (taxas de infecção equivalentes a 0,01, 0,1 e 1 caso por 100 habitantes) e horizontes temporais (1, 3 e 6 meses). Os resultados evidenciam uma situação crítica do sistema para atender essa demanda potencial, uma vez que diversas microrregiões e macrorregiões de saúde operariam além de sua capacidade, comprometendo o atendimento a pacientes principalmente aqueles com sintomas mais severos. O estudo apresenta três mensagens relevantes. Em primeiro lugar, é necessário reduzir a velocidade de propagação da COVID-19 na população brasileira, permitindo um tempo maior para a reorganização da oferta e aliviando a pressão sobre o sistema de saúde. Segundo, é necessário expandir o número de leitos disponíveis. Ainda que o setor privado contribua para amortecer o déficit de demanda, a oferta conjunta dos dois setores não seria suficiente em várias macrorregiões. A construção de hospitais de campanha é importante, tanto em locais onde historicamente há vazios assistenciais como também naqueles onde já se observa uma pressão do lado da demanda. A terceira mensagem diz respeito à organização regionalizada dos serviços de saúde que, apesar de adequada em situações de demanda usual, em momentos de pandemia este desenho implica desafios adicionais, especialmente se a distância que o paciente tiver de percorrer for muito grande.


El objetivo de este estudio es analizar la presión sobre el sistema de salud brasileño, ocasionada por la demanda adicional de camas hospitalarias y equipos de ventilación mecánica, generada por el COVID-19. Para tal fin, se realizó un conjunto de simulaciones, con el fin de estimar la demanda de camas generales (microrregiones de salud), camas de UTI y equipamientos de ventilación asistida (macrorregiones de salud) en diferentes escenarios, según la intensidad (tasas de infección equivalentes a 0,01, 0,1 y 1 caso por 100 habitantes) y horizontes temporales (1, 3 y 6 meses). Los resultados evidencian una situación crítica del sistema para atender esa demanda potencial, ya que diversas microrregiones y macrorregiones de salud operarían más allá de su capacidad, comprometiendo la atención a pacientes principalmente aquellos con los síntomas más graves. El estudio presenta tres mensajes relevantes. En primer lugar, es necesario reducir la velocidad de propagación del COVID-19 en la población brasileña, permitiendo un tiempo mayor para la reorganización de la oferta y aliviando la presión sobre el sistema de salud. En segundo lugar, es necesario expandir el número de camas disponibles. A pesar de que el sector privado contribuya a amortiguar el déficit de demanda, la oferta conjunta de los dos sectores no sería suficiente en varias macrorregiones. La construcción de hospitales de campaña es importante, tanto en lugares donde históricamente existen lagunas asistenciales, como también en aquellos donde ya se observa una presión por parte de la demanda. El tercer mensaje se refiere a la organización por regiones de los servicios de salud que, a pesar de ser adecuada en situaciones de demanda habitual, en momentos de pandemia, este diseño implica desafíos adicionales, especialmente si la distancia que el paciente tuviera que recorrer fuera muy lejana.


This study aims to analyze the pressure on the Brazilian health system from the additional demand created by COVID-19. The authors performed a series of simulations to estimate the demand for hospital beds (health micro-regions) as well as to ICU beds, and mechanical ventilators (health macro-regions) under different scenarios of intensity (infection rates equivalent to 0.01, 0.1, and 1 case por 100 inhabitants) and time horizons (1, 3, and 6 months). The results reveal a critical situation in the system for meeting this potential demand, with numerous health micro-regions and macro-regions operating beyond their capacity, compromising the care for patients, especially those with more severe symptoms. The study presents three relevant messages. First, it is necessary to slow the spread of COVID-19 in the Brazilian population, allowing more time for the reorganization of the supply and relieve the pressure on the health system. Second, the expansion of the number of available beds will be the key. Even if the private sector helps offset the deficit, the combined supply from the two sectors (public and private) would be insufficient in various macro-regions. The construction of field hospitals is important, both in places with a history of "hospital deserts" and in those already pressured by demand. The third message involves the regionalized organization of health services, whose design may be adequate in situations of routine demand, but which suffer additional challenges during pandemics, especially if patients have to travel long distances to receive care.


Subject(s)
Humans , Pneumonia, Viral/epidemiology , Ventilators, Mechanical/supply & distribution , Coronavirus Infections/epidemiology , Betacoronavirus , Health Services Needs and Demand/statistics & numerical data , Hospital Bed Capacity/statistics & numerical data , Intensive Care Units/supply & distribution , Pneumonia, Viral/prevention & control , Brazil/epidemiology , Public Sector/statistics & numerical data , Private Sector/statistics & numerical data , Coronavirus Infections/prevention & control , Pandemics/prevention & control , SARS-CoV-2 , COVID-19
9.
Estilos clín ; 24(3): 432-444, set.-dez. 2019.
Article in Portuguese | LILACS, Index Psychology - journals | ID: biblio-1279035

ABSTRACT

Partimos do dito mãe geladeira, que se apresenta na mídia especulativa como um representante da práxis psicanalítica, sobretudo na clínica das patologias infantis, e buscamos elucidar essa expressão como um equívoco necessitando de elaboração. Para tal, seguiremos pelos autores pós-freudianos, que se amparavam na maternagem para dizer do sujeito, posição que pode ter contribuído para esse equívoco, e nos dirigimos a Lacan, que elucida e diferencia o lugar da mãe mulher como uma função. Enfim, concluímos que esse dito, na atualidade, se revela como mais uma forma de ataque à psicanálise no que se refere ao tratamento das crianças autistas.


Partimos del clásico comentario de la "madre fría" como supuestamente representante de la praxis psicoanalítica, sobre todo en la clínica de las patologías infantiles, y buscamos elucidar esa expresión como un siendo equívoco que merece ser analizado. Para eso, seguiremos los autores post-freudianos que, apoyándose en el maternaje para decir del sujeto, contribuyeran con ese equívoco, posteriormente nos ocupamos de Lacan, que elucida y diferencia el lugar de la madre mujer como una función. Concluimos que esa idea de la "madre fría" revelase como una forma más de ataque al psicoanálisis en lo que se refiere al tratamiento de los niños autistas.


We start from the maxim refrigerator mother, which presents itself in the speculative media as a representative of the psychoanalytical practice, especially in the clinical of childhood pathologies, and we seek to elucidate this expression as a mistake requiring elaboration. For that, we will follow the post-Freudian authors, who took refuge in the maternity to say of the subject, a position that may have contributed to this misconception, and we address to Lacan, who elucidates and differentiates the place of the mother woman as a function. Finally, we conclude that this saying, nowadays, reveals itself as another form of attack on psychoanalysis with regard to the treatment of autistic children.


Subject(s)
Autistic Disorder/etiology , Maternal Behavior , Mother-Child Relations , Psychoanalysis
10.
Plant Physiol Biochem ; 142: 395-404, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31408843

ABSTRACT

The HVA22 gene has been isolated for the first time from the aleurone layer of barley (Hordeum vulgare). Here, we characterized the HVA22 family from citrus (C. clementina and C. sinensis). Twelve genes, 6 in each species, were identified as well as duplication events for some of them. The ORF size ranged from 235 to 804 bp and the protein molecular weight from 94 to 267 kDa. All the citrus HVA22 protein presented transmembrane location and conserved TB2/DP1/HVA22 region. Phylogenetic and gene expression analyses suggested that some citrus HVA22 play a role in flower and fruit development, and that gene expression may be regulated by hormone or environmental conditions. Other regulation levels were also predicted, such as alternative splicing and post-translational modifications. The overall data indicated that citrus HVA22 may be involved in vesicular traffic in stressed cells, and that CcHVA22d could be involved in dehydration tolerance.


Subject(s)
Citrus/genetics , Genes, Plant/genetics , Plant Proteins/genetics , Citrus/physiology , Citrus sinensis/genetics , Citrus sinensis/physiology , Dehydration , Gene Expression Regulation, Plant/genetics , Gene Expression Regulation, Plant/physiology , Genes, Plant/physiology , Hydrogen Peroxide/metabolism , Phylogeny , Plant Proteins/physiology , Plants, Genetically Modified , Promoter Regions, Genetic/genetics , Stress, Physiological , Nicotiana/genetics , Transcriptome
11.
Gerais (Univ. Fed. Juiz Fora) ; 11(2): [306 - 326], jul. 2018.
Article in Portuguese | LILACS | ID: biblio-914635

ABSTRACT

Em decorrência dos avanços tecnológicos, os jogos eletrônicos se tornaram cada vez mais populares. No entanto, existe uma grande preocupação em relação ao seu uso prejudicial e prolongado. O objetivo deste estudo foi realizar uma revisão bibliográfica da literatura acerca do modelo e tratamentos de base cognitivo-comportamentais para o uso prejudicial de jogos eletrônicos e conhecer sua etiologia, diagnóstico e prevalência. Para isso, foram realizadas buscas de textos nas bases de dados Pubmed, SciELO, Periódicos Capes e Google Acadêmico. Apesar do aumento do número de pessoas que têm apresentado problemas relacionados ao uso dos jogos eletrônicos, o presente trabalho mostrou que não se tem ainda designação, diagnóstico e tratamentos específicos para tal, e que tais elementos têm sido embasados nos estudos sobre dependência de internet e outros transtornos de controle do impulso. Entretanto, contamos por ora com achados muito importantes, no que diz respeito a cognições, comportamentos, emoções, domínios motivacionais, etiologia e semelhanças neurobiológicas com outros transtornos e norteadores para o tratamento.


As a result of technological advances, video-games have become increasingly popular. Despite the benefits of this technology, there is a big concern about its excessive and prolonged use. The goal of this study was to review the literature on the cognitive-behavioral treatments and model for harmful use of electronic games, and to know its etiology, diagnosis and prevalence. For this, Pubmed, SciELO, Capes Periodicals and Scholar Google databases were used. Despite the increase in the number of people who have presented problems related to the use of electronic games, the present study showed that there is no designation, diagnosis and specific treatments for this, and that such elements have been based on studies of internet addiction and other impulse control disorders. However, we count for the moment with very important findings, regarding cognitions, behaviors, emotions, motivational domains, etiology and neurobiological similarities with other disorders and guiding factors for the treatment.


Subject(s)
Cognitive Behavioral Therapy , Games, Recreational , Internet , Dependency, Psychological
12.
PLoS One ; 12(5): e0176878, 2017.
Article in English | MEDLINE | ID: mdl-28459876

ABSTRACT

The alternative oxidase (AOX) protein is present in plants, fungi, protozoa and some invertebrates. It is involved in the mitochondrial respiratory chain, providing an alternative route for the transport of electrons, leading to the reduction of oxygen to form water. The present study aimed to characterize the family of AOX genes in mandarin (Citrus clementina) and sweet orange (Citrus sinensis) at nucleotide and protein levels, including promoter analysis, phylogenetic analysis and C. sinensis gene expression. This study also aimed to do the homology modeling of one AOX isoform (CcAOXd). Moreover, the molecular docking of the CcAOXd protein with the ubiquinone (UQ) was performed. Four AOX genes were identified in each citrus species. These genes have an open reading frame (ORF) ranging from 852 bp to 1150 bp and a number of exons ranging from 4 to 9. The 1500 bp-upstream region of each AOX gene contained regulatory cis-elements related to internal and external response factors. CsAOX genes showed a differential expression in citrus tissues. All AOX proteins were predicted to be located in mitochondria. They contained the conserved motifs LET, NERMHL, LEEEA and RADE-H as well as several putative post-translational modification sites. The CcAOXd protein was modeled by homology to the AOX of Trypanosona brucei (45% of identity). The 3-D structure of CcAOXd showed the presence of two hydrophobic helices that could be involved in the anchoring of the protein in the inner mitochondrial membrane. The active site of the protein is located in a hydrophobic environment deep inside the AOX structure and contains a diiron center. The molecular docking of CcAOXd with UQ showed that the binding site is a recessed pocket formed by the helices and submerged in the membrane. These data are important for future functional studies of citrus AOX genes and/or proteins, as well as for biotechnological approaches leading to AOX inhibition using UQ homologs.


Subject(s)
Citrus/enzymology , Citrus/genetics , Mitochondrial Proteins/genetics , Mitochondrial Proteins/metabolism , Oxidoreductases/genetics , Oxidoreductases/metabolism , Plant Proteins/genetics , Plant Proteins/metabolism , Amino Acid Sequence , Conserved Sequence , Exons , Gene Expression Regulation, Plant/physiology , Hydrophobic and Hydrophilic Interactions , Mitochondria/metabolism , Molecular Docking Simulation , Phylogeny , Plant Structures/enzymology , Plant Structures/genetics , Promoter Regions, Genetic , Protein Processing, Post-Translational , Protein Structure, Secondary , Sequence Homology, Amino Acid , Species Specificity , Ubiquinone/metabolism
13.
Cad Saude Publica ; 29(9): 1805-15, 2013 Sep.
Article in Portuguese | MEDLINE | ID: mdl-24068226

ABSTRACT

This study aimed to map indicators of violence against women as recorded by primary healthcare services in Belo Horizonte, Minas Gerais State, Brazil, and to identify difficulties experienced by health professionals in reporting such violence. Epidemiological data on this type of notification were collected in the information system of the Municipal Health Department. Data were produced with a semi-structured questionnaire and three focus group sessions with participation by 270 primary care professionals. The data were submitted to content analysis and were coded, categorized, and discussed in light of a literature review. A central analytical axis was called (in)visibility of violence against women. The data revealed both the recognition of violence as a public health problem and the invisibility that prevents dealing with it properly. Notification of such violence is often viewed as a fuss or commotion, which hampers progress in discussing and acting on the problem.


Subject(s)
Attitude of Health Personnel , Battered Women/statistics & numerical data , Mandatory Reporting , Primary Health Care/statistics & numerical data , Spouse Abuse/statistics & numerical data , Brazil/epidemiology , Female , Humans , Primary Health Care/standards , Qualitative Research , Surveys and Questionnaires
14.
Cad. saúde pública ; 29(9): 1805-1815, Set. 2013. tab
Article in Portuguese | LILACS | ID: lil-686767

ABSTRACT

Esta pesquisa teve por objetivo mapear indicadores de violências contra mulheres em unidades básicas de saúde de Belo Horizonte, Minas Gerais, Brasil, e identificar as dificuldades experimentadas por profissionais de saúde na notificação de violências. Dados epidemiológicos sobre esse tipo de notificação foram levantados no sistema de informações da Secretaria Municipal de Saúde. Dados qualitativos foram produzidos com questionário semiestruturado e três sessões de grupos focais, com a participação de 270 profissionais da atenção primária à saúde. Os dados foram submetidos à análise de conteúdo, sendo codificados, categorizados e discutidos à luz da revisão de literatura. Um eixo analítico central foi denominado (in)visibilidade da violência contra mulheres. Emergem dos dados tanto o reconhecimento da violência como problema de saúde pública quanto a invisibilidade que impede o seu enfrentamento. Observa-se que a notificação é frequentemente tomada como denúncia, o que dificulta o avanço nas discussões e ações concernentes ao problema.


This study aimed to map indicators of violence against women as recorded by primary healthcare services in Belo Horizonte, Minas Gerais State, Brazil, and to identify difficulties experienced by health professionals in reporting such violence. Epidemiological data on this type of notification were collected in the information system of the Municipal Health Department. Data were produced with a semi-structured questionnaire and three focus group sessions with participation by 270 primary care professionals. The data were submitted to content analysis and were coded, categorized, and discussed in light of a literature review. A central analytical axis was called (in)visibility of violence against women. The data revealed both the recognition of violence as a public health problem and the invisibility that prevents dealing with it properly. Notification of such violence is often viewed as a fuss or commotion, which hampers progress in discussing and acting on the problem.


Esta investigación tiene como objetivo mapear indicadores de violencia contra las mujeres en las unidades básicas de Belo Horizonte, Minas Gerais, Brasil, e identificar las dificultades observadas por los profesionales de sanidad en la notificación de la violencia. Datos epidemiológicos sobre ese tipo de notificación fueron recogidos en el sistema de información de la Secretaría Municipal de Salud. Se consiguieron datos cualitativos mediante un cuestionario semiestructurado y tres sesiones de grupos focales, con la participación de 270 profesionales de atención primaria a la salud. Los datos fueron sometidos a un análisis de contenido, fueron codificados, categorizados y discutidos a la luz de la revisión de la literatura. Un eje analítico central fue denominado (in)visibilidad de la violencia contra las mujeres. Emergen dos datos, tanto el reconocimiento de la violencia como un problema de salud pública, como la invisibilidad que impide su enfrentamiento. Se observa que la notificación es frecuentemente entendida como denuncia, lo que dificulta el avance en las discusiones y acciones concernientes al problema.


Subject(s)
Female , Humans , Attitude of Health Personnel , Battered Women/statistics & numerical data , Mandatory Reporting , Primary Health Care/statistics & numerical data , Spouse Abuse/statistics & numerical data , Brazil/epidemiology , Primary Health Care/standards , Qualitative Research , Surveys and Questionnaires
15.
An Acad Bras Cienc ; 85(2): 519-32, 2013.
Article in English | MEDLINE | ID: mdl-23828358

ABSTRACT

Considering the importance of monitoring the water quality parameters, remote sensing is a practicable alternative to limnological variables detection, which interacts with electromagnetic radiation, called optically active components (OAC). Among these, the phytoplankton pigment chlorophyll a is the most representative pigment of photosynthetic activity in all classes of algae. In this sense, this work aims to develop a method of spatial inference of chlorophyll a concentration using Artificial Neural Networks (ANN). To achieve this purpose, a multispectral image and fluorometric measurements were used as input data. The multispectral image was processed and the net training and validation dataset were carefully chosen. From this, the neural net architecture and its parameters were defined to model the variable of interest. In the end of training phase, the trained network was applied to the image and a qualitative analysis was done. Thus, it was noticed that the integration of fluorometric and multispectral data provided good results in the chlorophyll a inference, when combined in a structure of artificial neural networks.


Subject(s)
Chlorophyll/analysis , Environmental Monitoring/methods , Neural Networks, Computer , Water Quality , Chlorophyll A , Models, Theoretical , Remote Sensing Technology , Spectrum Analysis
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