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1.
Arch. bronconeumol. (Ed. impr.) ; 48(8): 274-279, ago. 2012. ^tab, graf
Article in Spanish | IBECS | ID: ibc-103788

ABSTRACT

Antecedentes: Los pacientes con infarto cerebral presentan a menudo un deterioro del nivel de conciencia que hace que la extubación no sea satisfactoria. El objetivo de este estudio fue evaluar los componentes de la mecánica respiratoria que pudieran estar relacionados con el éxito de la extubación en pacientes con ictus. Métodos: Se incluyó en el estudio a 20 pacientes consecutivos con ictus que necesitaron apoyo de ventilación mecánica. Se efectuaron determinaciones de la presión inspiratoria máxima, la presión gástrica y esofágica (Pdi/Pdimáx), el volumen-minuto, la frecuencia respiratoria, la elasticidad estática, la resistencia de las vías aéreas (RAW), el índice de respiración rápida y superficial (RSRI), la relación tiempo inspiratorio/tiempo de ciclo respiratorio total (Ti/Ttot) y la PaO2/FiO2. Resultados: El grupo de pacientes que pudieron ser extubados con éxito tenía un tiempo de permanencia en ventilación mecánica de 12,5±2,2días, en comparación con 13,1±2días en el grupo en el que fracasó el proceso de extubación. La media Ti/Ttot y de Pdi/Pdimáx en el grupo de fracaso de la extubación fue de 0,4±0,08 (0,36 a 0,44) y de 0,5±0,7 (0,43 a 0,56), respectivamente. La relación Ti/Ttot fue de 0,37±0,05 (0,34 a 0,41; p=0,0008) y la relación Pdi/Pdimáx fue de 0,25±0,05 en el grupo de extubación satisfactoria (0,21 a 0,28; p<0,0001). Se observó una correlación entre la relación Pdi/Pdimáx y el RSRI (r=0,55; p=0,009) y la PaO2/FiO2 (r=-0,59; p=0,005). Los pacientes que tenían valores altos de RSRI (OR, 3,66; p=0,004) y Pdi (OR, 7,3; p=0,002) o valores bajos de PaO2/FiO2 (OR, 4,09; p=0,007), Pdi/Pdimáx (OR, 4,12; p=0,002) y RAW (OR, 3,0; p=0,02) presentaron un fracaso de la extubación de la ventilación mecánica. Conclusión: El índice de fatiga muscular es una variable predictiva importante del proceso de extubación en pacientes con ictus en los que se ha utilizado una ventilación mecánica prolongada(AU)


Background: Patients with cerebral infarction often present impaired consciousness and unsatisfactory extubation. We aimed to assess the respiratory mechanics components that might be associated with the success of extubation in stroke patients. Methods: Twenty consecutive patients with stroke who needed mechanical ventilation support were enrolled. The maximal inspiratory pressure, gastric and the esophageal pressure (Pdi/Pdimax), minute volume, respiratory rate, static compliance, airway resistance, rapid and superficial respiration index (RSRI), inspiratory time/total respiratory cycle (Ti/Ttot), and PaO2/FiO2 were measured. Results: The group who presented success to the extubation process presented 12.5±2.2=days in mechan-ical ventilation and the group who failed presented 13.1±2=days. The mean Ti/Ttot and Pdi/Pdimax for the failure group was 0.4±0.08 (0.36-0.44) and 0.5±0.7 (0.43-0.56), respectively. The Ti/Ttot ratio was 0.37±0.05 (0.34-0.41; p=0.0008) and the Pdi/Pdimax was 0.25±0.05 for the success group (0.21-0.28; p<0.0001). A correlation was found between Pdi/Pdimax ratio and the RSRI (r=0.55; p=0.009) and PaO2/FiO2 (r=−0.59; p=0.005). Patients who presented a high RSRI (OR, 3.66; p=0.004) and Pdi (OR, 7.3; p=0.002), and low PaO2/FIO2 (OR, 4.09; p=0.007), Pdi/Pdimax (OR, 4.12; p=0.002) and RAW (OR, 3.0; p=0.02) developed mechanical ventilation extubation failure. Conclusion: Muscular fatigue index is an important predicting variable to the extubation process in prolonged mechanical ventilation of stroke patients(AU)


Subject(s)
Humans , Male , Female , Young Adult , Adult , Middle Aged , Aged , Aged, 80 and over , Respiration, Artificial , Airway Extubation , Stroke , Respiratory Muscles , Respiratory Mechanics , Cerebral Infarction , Prospective Studies , Cohort Studies , Observational Studies as Topic
2.
Arch Bronconeumol ; 48(8): 274-9, 2012 Aug.
Article in English, Spanish | MEDLINE | ID: mdl-22607984

ABSTRACT

BACKGROUND: Patients with cerebral infarction often present impaired consciousness and unsatisfactory extubation. We aimed to assess the respiratory mechanics components that might be associated with the success of extubation in stroke patients. METHODS: Twenty consecutive patients with stroke who needed mechanical ventilation support were enrolled. The maximal inspiratory pressure, gastric and the esophageal pressure (Pdi/Pdimax), minute volume, respiratory rate, static compliance, airway resistance, rapid and superficial respiration index (RSRI), inspiratory time/total respiratory cycle (Ti/Ttot), and PaO(2)/FiO(2) were measured. RESULTS: The group who presented success to the extubation process presented 12.5±2.2=days in mechanical ventilation and the group who failed presented 13.1±2=days. The mean Ti/Ttot and Pdi/Pdimax for the failure group was 0.4±0.08 (0.36-0.44) and 0.5±0.7 (0.43-0.56), respectively. The Ti/Ttot ratio was 0.37±0.05 (0.34-0.41; p=0.0008) and the Pdi/Pdimax was 0.25±0.05 for the success group (0.21-0.28; p<0.0001). A correlation was found between Pdi/Pdimax ratio and the RSRI (r=0.55; p=0.009) and PaO(2)/FiO(2) (r=-0.59; p=0.005). Patients who presented a high RSRI (OR, 3.66; p=0.004) and Pdi (OR, 7.3; p=0.002), and low PaO(2)/FIO(2) (OR, 4.09; p=0.007), Pdi/Pdimax (OR, 4.12; p=0.002) and RAW (OR, 3.0; p=0.02) developed mechanical ventilation extubation failure. CONCLUSION: Muscular fatigue index is an important predicting variable to the extubation process in prolonged mechanical ventilation of stroke patients.


Subject(s)
Airway Extubation , Brain Stem Infarctions/physiopathology , Respiratory Mechanics , Respiratory Muscles/physiopathology , Ventilator Weaning , Aged , Airway Resistance , Body Mass Index , Brain Stem Infarctions/complications , Brain Stem Infarctions/therapy , Consciousness Disorders/etiology , Female , Humans , Lung Compliance , Male , Manometry , Middle Aged , Muscle Fatigue , Prospective Studies , Respiration, Artificial , Respiratory Function Tests , Tidal Volume
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