A Smartphone App for Real-Time Assessment of Malaria Prophylaxis Adverse Events.

Background: Growth of international travel to malarial areas over the last decades has contributed to more travelers taking malaria prophylaxis. Travel-related symptoms may be wrongly attributed to malaria prophylaxis and hinder compliance. Here, we aimed to assess the frequency of real-time reporting of symptoms by travelers following malaria prophylaxis using a smartphone app. Method: Adult international travelers included in this single-center study (Barcelona, Spain) used the smartphone Trip Doctor® app developed by our group for real-time tracking of symptoms and adherence to prophylaxis. Results: Six hundred four (n = 604) international travelers were included in the study; 74.3% (449) used the app daily, and for one-quarter of travelers, malaria prophylaxis was prescribed. Participants from the prophylaxis group traveled more to Africa (86.7% vs. 4.3%; p < 0.01) and to high travel medical risk countries (60.8% vs. 18%; p < 0.01) and reported more immunosuppression (30.8% vs. 23.1% p < 0.01). Regarding symptoms, no significant intergroup differences were observed, and no relationship was found between the total number of malarial pills taken and reported symptoms. Conclusions: In our cohort, the number of symptoms due to malaria prophylaxis was not significantly higher than in participants for whom prophylaxis was not prescribed, and the overall proportion of symptoms is higher compared with other studies.

Training small producers in Good Manufacturing Practices for the development of goat milk cheese

Abstract Training in Good Manufacturing Practices enhances quality during food processing. This paper evaluates GMP training aimed at improving the chemical, sensory and microbiological quality of goat milk cheese. We worked with 26 families that produce cheese as their main source of income. Semi-structured interviews and observation were conducted to select relevant topics. The manufacturing processes were compared and samples were analyzed before and after GMP training. We trained 80% of the producers. Before receiving training, they used to make cheese from raw milk in unhygienic conditions and with little equipment. The products obtained had bad sensory characteristics, cracks, eyes on the pasta, a high number of aerobic mesophilic bacteria and total coliforms. After training, the producers pasteurized the milk and standardized processing procedures, resulting in final products that contained higher protein and calcium content, suitable sensory characteristics, and a significant reduction in microorganisms, with total coliforms falling to ≤ 5.103 UFC/g. Therefore, this study shows that the manufacturing process and the chemical, sensory and microbiological parameters of goat milk cheese improved after GMP training.

Perfil epidemiológico de menores de 6 años con malnutrición por déficit, de pueblos originarios de Santa Victoria Este. Salta 2018 / Epidemiological profile of children under 6 years of age with malnutrition due to deficit, from native towns of Santa Victoria Este, Salta 2018

INTRODUCCION La desnutrición infantil afecta especialmente a los niños menores de 6 años de pueblos originarios del Área Operativa VIII, Santa Victoria Este, en la provincia de Salta. OBJETIVOS Describir el perfil epidemiológico de niños < de 6 años con malnutrición por déficit. MÉTODOS Estudio Observacional Descriptivo, Análisis de Situación de salud, se evaluaron antropométricamente a 730 niños y niñas, entre 0 meses y 5 años 11 meses y 29 días de pueblos originarios, de los cuales 150 resultaron con algún grado de Déficit Nutricional, constituyendo la muestra intencional investigada. Para la evaluación del Estado Nutricional (E.N) se utilizaron los siguientes parámetros; para < de 2 años P/E y para > de 2 años P/T y se estudiaron variables demográficas, socioeconómicas y la situación alimentaria y nutricional. El análisis estadístico incluyó distribución de frecuencia según variables de estudio y chi2 como medida de asociación. RESULTADOS De los niños evaluados el 20,5% resultaron con Déficit Nutricional; el riesgo de padecerlo se incrementa en los > de 2 años. La asociación estadística entre edad y déficit nutricional es significativa con (p≤ 0.05). Los niños no cubren en su mayoría el % de adecuación de macro y micronutrientes como así mismo no cubren su requerimiento energético diario. La TMI;17,19 ‰ y TMM<5a; 31,94 ‰ superan ampliamente los indicadores provinciales y nacionales. DISCUSIÓN La investigación muestra los gradientes de la problemática nutricional en la población evaluada que depende de factores económicos, sociales, políticos, del sistema de salud, geográficos, demográficos, que impacta en los indicadores de morbimortalidad en esta población. Esta situación exige de respuestas intersectoriales que aborden la realidad holísticamente y en concordancia con las necesidades particulares de las comunidades originarias