ABSTRACT
Paraquat is a common herbicide in Spain. In our country there are a few cases of this intoxication and it presents a high mortality even if the patients ingest a minimal amount. We present two cases of accidental poisoning with paraquat. These patients were admitted three hours after ingestion of toxin. They were treated with with orogastric lavage, activated charcoal, N-acetylcysteine, Fuller's earth, cathartics, support measures and hemoperfusion with activated charcoal. With these treatments both patients had a undetectable levels of paraquat 48 hours after and improvement of their symptoms, gastric and intestinal predominantly . We present the graphics of evolution of the plasma and urine levels of paraquat in both patients. We review the different aspects of treatment and update of this poisoning.
Subject(s)
Charcoal/therapeutic use , Diatomaceous Earth/therapeutic use , Hemoperfusion , Paraquat/poisoning , Accidents , Acetylcysteine/therapeutic use , Aged , Antioxidants/therapeutic use , Cathartics/therapeutic use , Female , Fluid Therapy , Gastric Lavage , Glucose/therapeutic use , Humans , Male , Middle Aged , Paraquat/blood , Paraquat/urine , Poisoning/therapyABSTRACT
El Paraquat es un herbicida del grupo de los biperidilicos, de los más utilizados en nuestro pais.En España existen muy pocos casos descritos de esta intoxicación y presenta una alta mortalidad incluso con la ingestión de mínimas cantidades.Presentamos dos casos de intoxicación por ingesta accidental de este producto, que llegan a nuestro hospital en las tres horas posteriores. Se instaura tratamiento con lavado gástrico, carbón activado, N acetil cisteina, tierra de Fuller, catárticos, medidas de apoyo y hemoperfusión con carbón activado; consiguiendose niveles indetectables del tóxico 48 horas después y mejorando su sintomatología, predominantemente gastrointestinal.Se comentan los casos clínicos durante su estancia en U.C.I así como aspectos clínicos de estas intoxicaciones, su tratamiento actual y últimas tendencias y factores pronósticos (AU)
The Paraquat is a herbicide more using in Spain. In our country there are a few cases this intoxication and it presents a hight mortality even if the patients ingest a minimal amount. We present two cases of casual poisoning with paraquat. These patients were admited three hours after ingestion of toxic. They were treated with with orogastric lavage, activated charcoal, N-acetil-cysteina, Fuller´s earth, catartics, support measuring and hemperfusion with activated charcoal, with this treatments both patients had a indetectable levels of paraquat 48 hours after and yours symptoms that was gastric and intestinal predominantly had missing. We present the graphics of evolution the plasmatic and urine levels of paraquat the both patients. We review the differents aspects of treatment and update of this intoxication (AU)
