ABSTRACT
Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profile analysis split by sex yielded two clusters common to both sexes (a Homogeneous group, 53% and 79.3%, and an Indecisive group, 18.3% and 8.6% of males and females, respectively), a specific male profile characterized by presenting jumping to conclusions (28.7%) and a specific female profile characterized by cognitive biases (12.1%). Males and females in the homogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may benefit from specific targeted treatment and highlights the need to consider sex when planning interventions.
Subject(s)
Cognition Disorders , Metacognition , Psychotic Disorders , Cognition , Cognition Disorders/psychology , Female , Humans , Male , Psychotic Disorders/therapy , Social CognitionABSTRACT
Subjects with first-episode psychosis experience substantial deficits in social cognition and metacognition. Although previous studies have investigated the role of profiles of individuals in social cognition and metacognition in chronic schizophrenia, profiling subjects with first-episode psychosis in both domains remains to be investigated. We used latent profile analysis to derive profiles of the abilities in 174 persons with first-episode psychosis using the Beck's Cognitive Insight Scale, the Faces Test, the Hinting Task, the Internal, Personal and Situational Attributions Questionnaire, and the Beads Task. Participants received a clinical assessment and a neuropsychological assessment. The best-fitting model was selected according to the Bayesian information criterion (BIC). We assessed the importance of the variables via a classification tree (CART). We derived three clusters with distinct profiles. The first profile (33.3%) comprised individuals with low social cognition. The second profile (60.9%) comprised individuals that had more proneness to present jumping to conclusions. The third profile (5.7%) presented a heterogeneous profile of metacognitive deficits. Persons with lower social cognition presented worse clinical and neuropsychological features than cluster 2 and cluster 3. Cluster 3 presented significantly worst functioning. Our results suggest that individuals with FEP present distinct profiles that concur with specific clinical, neuropsychological, and functional challenges. Each subgroup may benefit from different interventions.
ABSTRACT
Facial emotion recognition refers to a person's interpretation of facial features of another to identify a particular emotional state. It is essential in human evolution and encompasses distinct neural networks. Facial emotion recognition is altered in most neurodegenerative diseases, but literature just focus on single neurological pathologies or limited comparison with psychiatric pathologies. It is unknown if a common pattern of affection through pathologies exists or if facial emotion recognition changes according to the underlying pathology. This review discusses its development in healthy population, synthesizes facial emotion recognition studies regarding most common neurological diseases, as well as most relevant findings in neuroimaging and current treatments. Facial emotion recognition, especially negative emotions, is altered in all described neurodegenerative diseases and could constitutes an early marker of cognitive deterioration.
TITLE: Reconocimiento facial de emociones en trastornos neurologicos: una revision narrativa.El reconocimiento facial de emociones hace referencia a la interpretacion de una persona sobre los rasgos faciales de otra para identificar un determinado estado emocional. Es esencial en la evolucion humana y abarca distintas redes neuronales. A pesar de que el reconocimiento facial de emociones se ve alterado en la mayoria de las enfermedades neurodegenerativas, la bibliografia solo se centra en patologias neurologicas individuales o en limitadas comparaciones con patologias psiquiatricas. Se desconoce si existe un patron comun de alteracion entre las patologias o si el reconocimiento facial de emociones cambia segun el trastorno subyacente. Esta revision describe su desarrollo en poblacion sana y sintetiza los estudios de reconocimiento facial de emociones en relacion con las enfermedades neurologicas mas comunes, asi como los hallazgos mas relevantes de neuroimagen y los tratamientos actuales. El reconocimiento facial de emociones, especialmente en emociones negativas, esta alterado en todas las enfermedades neurodegenerativas descritas y podria constituir en algunos casos un marcador temprano de deterioro cognitivo.
