Correction: Pakhomova et al. High-Entropy Diborides-Silicon Carbide Composites by Reactive and Non-Reactive Spark Plasma Sintering: A Comparative Study. Materials 2024, 17, 718.

In the original publication [...].

High-Entropy Diborides-Silicon Carbide Composites by Reactive and Non-Reactive Spark Plasma Sintering: A Comparative Study.

The reactive spark plasma sintering (R-SPS) method was compared in this work with the two-step SHS-SPS route, based on the combination of the self-propagating high-temperature synthesis (SHS) with the SPS process, for the fabrication of dense (Hf0.2Mo0.2Ti0.2Ta0.2Nb0.2)B2-SiC and (Hf0.2Mo0.2Ti0.2Ta0.2Zr0.2)B2-SiC ceramics. A multiphase and inhomogeneous product, containing various borides, was obtained at 2000 °C/20 min by R-SPS from transition metals, B4C, and Si. In contrast, if the same precursors were first reacted by SHS and then processed by SPS under the optimized condition of 1800 °C/20 min, the desired ceramics were successfully attained. The resulting sintered samples possessed relative densities above 97% and displayed uniform microstructures with residual oxide content <2.4 wt.%. The presence of SiC made the sintering temperature milder, i.e., 150 °C below that needed by the corresponding additive-free system. The fracture toughness was also markedly improved, particularly when considering the Nb-containing system processed at 1800 °C/20 min, whereas the fracture toughness progressively decreased (from 7.35 to 5.36 MPa m1/2) as the SPS conditions became more severe. SiC addition was found to inhibit the volatilization of metal oxides like MoO3 formed during oxidation experiments, thus avoiding mass loss in the ceramics. The benefits above also likely took advantage of the fact that the two composite constituents were synthesized in parallel, according to the SHS-SPS approach, rather than being produced separately and combined subsequently, so that strong interfaces between them were formed.

Assessment of Metallurgical and Mechanical Properties of Welded Joints via Numerical Simulation and Experiments.

Welding has been the most important joining technique applied to metallic materials since the early twentieth century when arc welding was introduced [...].

Rapid Calculation of Residual Stresses in Dissimilar S355-AA6082 Butt Welds.

An analytical model is proposed to rapidly capture the thermal and residual stresses values induced by the hybrid metal extrusion and bonding (HYB) process on dissimilar-metal butt-welded joints. The power input for two welding velocities is first assessed using a thermal-mechanical model solved by a heat generation routine written in MATLAB code. Subsequently, the obtained temperature history is used as input to solve the equilibrium and compatibility equations formulated to calculate the thermal and residual stresses. To verify the soundness of the analytical approach, a Finite Element numerical model of the entire process is carried out and results are compared with those coming from the proposed rapid method. It is found that the degree of accuracy reached by the analytical model is excellent, especially considering the tremendous time reduction when compared to that characterizing the standard numerical approach.

Residual Notch Stress Intensity Factors in Welded Joints Evaluated by 3D Numerical Simulations of Arc Welding Processes.

Approaches based on calculating Residual Notch Stress Intensity Factors (R-NSIFs) assume the weld toe to be a sharp V-notch that gives rise to a residual singular stress distribution close to the weld toe. Once R-NSIFs are determined, they might be included in local fatigue criteria for the structural strength assessment of welded joints based on NSIFs due to external cyclic loading. However, the numerical calculation of R-NSIFs through finite element (FE) simulations of the welding process requires extremely refined meshes to properly capture the residual stress singularity. In this context, the Peak Stress Method (PSM) has recently been adopted to estimate R-NSIFs due to residual stresses by means of coarse meshes of 2D 4-node plane or 3D 8-node brick elements. The aim of this work is to investigate the applicability of the PSM to estimate R-NSIFs in a butt-welded joint using coarse meshes of 3D 10-node tetra elements. The R-NSIF distribution at the weld toe line is estimated by applying the PSM to coarse meshes of 3D 10-node tetra elements, and the results are in agreement with those obtained using 3D 8-node brick elements. Accordingly, the PSM based on tetra elements further enhances the rapid estimation of R-NSIFs using coarse meshes and could be effective in analyzing complex 3D joint geometries.

The effect of Equal Channel Angular Pressing on the stress corrosion cracking susceptibility of AZ31 alloy in simulated body fluid.

Despite the great potential of Mg and its alloys as material for biodegradable implants, their low resistance to the simultaneous action of corrosion and mechanical stresses in the human body have hampered their use. Stress Corrosion Cracking has been reported as one of the most critical failure modes to overcome to allow such materials to be clinically applied. Thus, in this paper we investigate the effect of Equal Channel Angular Pressing (ECAP) on the Stress Corrosion Cracking (SCC) susceptibility of the AZ31 Mg alloy. To do so, AZ31 alloy has been subjected to 1, 2 and 4 passes of ECAP, and the samples so obtained have then been tested by means Slow Strain Rate Tests (SSRTs) in Simulated Body Fluid (SBF) at 37 °C. Samples subjected to one pass of ECAP are shown to be less susceptible to SCC compared to the material in the as-received condition, while further ECAP processing (2 and 4 passes) are found to worsen the SCC susceptibility. To understand the different SCC susceptibilities shown by the differently ECAPed samples, microstructural analyses, potentiodynamic polarization curves, hydrogen evolution experiments and Scanning Electron Microscopy (SEM) analyses of the fracture surfaces were carried out. The improved corrosion resistance of the samples subjected to 1 pass of ECAP compared to the samples in the as received condition (due to a finer grain size) and to the samples subjected to 2 and 4 passes (due to a more favourable texture evolution) represents the reason of their reduced SCC susceptibility.

A Semi-Analytical Model for the Heat Generation during Hybrid Metal Extrusion and Bonding (HYB).

Hybrid Metal Extrusion and Bonding (HYB) is a novel solid-state welding method for metals and alloys that utilises continuous extrusion as a technique to enable aluminium filler metal additions. In the present study, a new semi-analytical model for the heat generation during aluminium butt welding is presented. As a starting point, the classical Rosenthal thin plate solution for the pseudo-steady-state temperature distribution around a fully penetrating line source is invoked. Then, the associated heat generation is calculated by considering the individual contributions from the tip of the rotating pin, the pin shoulder, and the filler metal additions on the net power input. In a calibrated form, the model yields thermal efficiency factors that are in close agreement with those obtained from more sophisticated finite element analyses but with considerably less computational effort.

Fatigue Behavior of Porous Ti-6Al-4V Made by Laser-Engineered Net Shaping.

The fatigue behavior and fracture mechanisms of additively manufactured Ti-6Al-4V specimens are investigated in this study. Three sets of testing samples were fabricated for the assessment of fatigue life. The first batch of samples was built by using Laser-Engineered Net Shaping (LENS) technology, a Direct Energy Deposition (DED) method. Internal voids and defects were induced in a second batch of samples by changing LENS machine processing parameters. Fatigue performance of these samples is compared to the wrought Ti-6Al-4V samples. The effects of machine-induced porosity are assessed on mechanical properties and results are presented in the form of SN curves for the three sets of samples. Fracture mechanisms are examined by using Scanning Electron Microscopy (SEM) to characterize the morphological characteristics of the failure surface. Different fracture surface morphologies are observed for porous and non-porous specimens due to the combination of head write speed and laser power. Formation of defects such as pores, unmelted regions, and gas entrapments affect the failure mechanisms in porous specimens. Non-porous specimens exhibit fatigue properties comparable with that of the wrought specimens, but porous specimens are found to show a tremendous reduced fatigue strength.

Strain Evolution in Cold-Warm Forged Steel Components Studied by Means of EBSD Technique.

Electron BackScatter Diffraction (EBSD) in conjunction with Field-Emission Environmental Scanning Electron Microscopy (FEG-ESEM) has been used to evaluate the microstructural and local plastic strain evolution in different alloys (AISI 1005, AISI 304L and Duplex 2205) deformed by a single-stage cold and warm forging process. The present work is aimed to describe the different behavior of the austenite and ferrite during plastic deformation as a function of different forging temperatures. Several topological EBSD maps have been measured on the deformed and undeformed states. Then, image quality factor, distributions of the grain size and misorientation have been analyzed in detail. In the austenitic stainless steel, the γ-phase has been found to harden more easily, then α-phase and γ-phase in AISI 1005 and in duplex stainless steel, sequentially. Compared to the high fraction of continuous dynamic recrystallized austenitic zones observed in stainless steels samples forged at low temperatures, the austenitic microstructure of samples forged at higher temperatures, 600-700 °C, has been found to be mainly characterized by large and elongated grains with some colonies of fine nearly-equiaxed grains attributed to discontinuous dynamic recrystallization.

Immunomodulation of TGF-beta 1 in mdx mouse inhibits connective tissue proliferation in diaphragm but increases inflammatory response: implications for antifibrotic therapy.

Irreversible connective tissue proliferation in muscle is a pathological hallmark of Duchenne muscular dystrophy (DMD), a genetic degenerative muscle disease due to lack of the sarcolemmal protein dystrophin. Focal release of transforming growth factor-beta1 (TGF-beta1) is involved in fibrosis development. Murine muscular dystrophy (mdx) is genetically homologous to DMD and histopathological alterations comparable to those in DMD muscles occur in diaphragm of older mdx mice. To investigate the early development of fibrosis and TGF-beta1 involvement, we assessed diaphragms in 6-36-week-old mdx and C57/BL6 (control) mice for fibrosis, and used real-time PCR and ELISA to determine TGF-beta1 expression. Significantly greater fibrosis and TGF-beta1 expression were found in mdx from the 6th week. Mice treated with neutralizing antibody against TGF-beta1 had lower levels of TGF-beta1 protein, reduced fibrosis, unchanged muscles fiber degeneration/regeneration, but increased inflammatory cells (CD4+lymphocytes). These data demonstrate early and progressive fibrosis in mdx diaphragm accompanied by TGF-beta1 upregulation. Reduction of TGF-beta1 appears promising as a therapeutic approach to muscle fibrosis, but further studies are required to evaluate long term effects of TGF-beta1 immunomodulation on the immune system.

First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant.

BN 82270 is a membrane-permeable prodrug of a chimeric compound (BN 82204) dually acting as calpain inhibitor and anti-oxidant. Acute in vivo injection of dystrophic mdx mice (30 mg/kg, s.c.) fully counteracted calpain overactivity in diaphragm. A chronic 4-6 weeks administration significantly prevented in vivo the fore limb force drop occurring in mdx mice exercised on treadmill. Ex vivo electrophysiological recordings showed that BN 82270 treatment contrasted the decrease in chloride channel function (gCl) in diaphragm, an index of spontaneous degeneration, while it was less effective on both exercise-impaired gCl and calcium-dependent mechanical threshold of the hind limb extensor digitorum longus (EDL) muscle fibres. The BN 82270 treated mdx mice showed a marked reduction of plasma creatine kinase and of the pro-fibrotic cytokine TGF-beta1 in both hind limb muscles and diaphragm; however, the histopathological profile of gastrocnemious muscle was poorly ameliorated. In hind limb muscles of treated mice, the active form was detected by HPLC in the low therapeutic concentration range. In vitro exposure to 100 microM BN 82270 led to higher active form in diaphragm than in EDL muscle. This is the first demonstration that this class of chimeric compounds, dually targeting pathology-related events, exerts beneficial effects in muscular dystrophy. The drug/prodrug system may require posology adjustment to produce wider beneficial effects on all muscle types.