Subject(s)
Diaphragm/abnormalities , Abnormalities, Multiple/diagnosis , Fatal Outcome , Humans , Infant, Newborn , Male , SyndromeABSTRACT
Focal abnormalities of gyration (FAG) are developmental disorders that may occur in isolated patients or, as in the case being reported, as part of a familial disorder. Analysis of individuals in a family spanning three generations was carried out using MRI. Abnormalities, present in all members of generations II and III, included focal cortical dysplasia (three patients), focal cortical infolding (two patients) and schizencephaly (one patient); associated minor anomalies, such as white matter abnormalities, were seen in the remaining three members of generations II and III. MRI recognition of FAG in the family being reported proved useful in defining their phenotypical expression and providing proper counselling for individual family members.
Subject(s)
Brain Diseases/genetics , Cerebral Cortex/abnormalities , Choristoma/genetics , Magnetic Resonance Imaging , Neurons , Adult , Aged , Brain Diseases/diagnosis , Cerebral Cortex/pathology , Choristoma/diagnosis , Electroencephalography , Epilepsies, Partial/diagnosis , Epilepsies, Partial/genetics , Female , Humans , Karyotyping , Male , Middle Aged , Pedigree , Tomography, X-Ray ComputedABSTRACT
A survey conducted in 52,000 young male subjects evaluated the influence of listening to music with stereophonic headphones on perception hypacusis leading to exemption from National Service. Also investigated were noise level output from promenaders as well as temporary auditory loss two minutes after listening for one hour. Findings suggested relative innocuity of listening at moderate intensity for less than seven hours weekly. Users exceeding these optimal factors develop professional type deafness for which similar preventive measures are required. Particular mention is made of the effect of strolling listeners on vigilance and on sound pollution of industrialized countries.
Subject(s)
Hearing Loss, Noise-Induced/etiology , Music , Adolescent , Adult , Audiometry , France , Hearing Loss, Noise-Induced/diagnosis , Hearing Loss, Noise-Induced/epidemiology , Humans , MaleABSTRACT
The appearance of new generations of firearms, very harmful for the hearing of the shooter, suggested the need for an updated review of data concerning detonations and their effect on hearing. Emphasis is given to the place of acoustic injuries among traumatic pressure-induced otopathies as well as the value and efficacy of current therapeutic measures.
Subject(s)
Firearms , Hearing Loss, Noise-Induced/physiopathology , Ear/pathology , Ear/physiology , Hearing Loss, Noise-Induced/etiology , Hearing Loss, Noise-Induced/therapy , HumansABSTRACT
The authors report a series of 13 cases of bony metastases leading to the discovery of a hepatoma. They were subjects of male sex, average age 64 years. Nine were severe alcoholics. The presenting symptoms were in 7 cases neurological, in four cases an isolated bone tumour, finally, one spontaneous fracture, and one case with pain alone. Severe loss of weight was frequent; in 10 cases out of 13 it was greater than 5 kg. Hepatomegaly was found in 8 cases, but in 3 cases there was no sign suggesting liver disease. In 7 cases out of nine, the metastases were already numerous at the time of diagnosis. The diagnosis of metastases from a hepatoma was made on the bone histology 11 times and from the hepatic histology in 6 cases. The histological of the bone metastasis reproduces very well that of the liver. In four cases there was local secretion of bile, in one case the metastatic liver cells underwent steatonecrosis.
