1.
Arch Dermatol Res (1975)
; 254(1): 23-8, 1975 Nov 14.
Article
in English
| MEDLINE
| ID: mdl-975
ABSTRACT
The subcellular distribution of phosphatases, proteinases, and ribonucleases of normal human stratum corneum and psoriatic scales was determined after differential centrifugation. All psoriatic enzymes showed much increased activities as compared to the normal stratum corneum enzymes. The highest activities of alkaline phosphatase from psoriatic scales could be detected in the nuclear fraction. The main activities of all other tested phosphatases and proteinases were present in the cytoplasmatic fraction. The subcellular distribution of the ribonucleases varied according to the pH value.
Subject(s)
Peptide Hydrolases/metabolism , Phosphoric Monoester Hydrolases/metabolism , Psoriasis/enzymology , Ribonucleases/metabolism , Skin/enzymology , Alkaline Phosphatase/metabolism , Cell Nucleus/enzymology , Cytoplasm/enzymology , Hydrogen-Ion Concentration , Subcellular Fractions/enzymology
2.
Dermatologica
; 149(5): 274-83, 1974.
Article
in English
| MEDLINE
| ID: mdl-4461304