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2.
Biomed Res Int ; 2018: 2059464, 2018.
Article in English | MEDLINE | ID: mdl-30228982

ABSTRACT

INTRODUCTION: Orofacial clefts are congenital malformations characterized by an incomplete shaping of structures that separate the nasal from the oral cavity and can affect the right, left, or both sides. The aim of the present study is to assess, with clinical, radiographical, and histological evaluations, the efficacy of piezoelectric devices compared to traditional rotating instruments in the bone harvesting in patients with history of cleft. MATERIALS AND METHODS: We have conducted a retrospective analysis on 20 patients with a history of orofacial clefts that were operated on from February 2014 to June 2017. The patients were divided into two groups: Group R in which bone graft was harvested using a burr and Group P in which the bone graft was obtained by a piezoelectric device. After a healing period of 8 months from the grafting procedure, clinical and radiographic evaluations were performed. RESULTS AND DISCUSSION: The use of the piezoelectric devices in bone harvesting allows a slight improvement in the final volume. This supports a faster integration into the receiving site. CONCLUSIONS: The use of piezoelectric device in patients with history of orofacial cleft that needed bone graft represents a method to be taken into consideration because it has interesting advantages.


Subject(s)
Bone Transplantation/instrumentation , Cleft Lip/surgery , Cleft Palate/surgery , Adolescent , Female , Humans , Male , Reproducibility of Results , Retrospective Studies , Young Adult
3.
Eur J Paediatr Dent ; 16(3): 229-32, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26418927

ABSTRACT

AIM: To examine the prevalence of different types of dental anomalies in children with nonsyndromic cleft lip, unilateral cleft lip-palate, and bilateral cleft lip-palate. MATERIALS AND METHODS: A sample of 90 patients (aged 4-20 years) affected by isolated cleft lip, unilateral and bilateral cleft lip and palate was examined. Cleft patients were classified into one of three groups according to cleft type: (1) Unilateral Cleft Lip-Palate, (2) Bilateral Cleft Lip-Palate, and (3) Cleft Lip. Intraoral exams, panoramic radiographs and dental casts, were used to analyse the prevalence of the various dental anomalies included in this study. RESULTS: There were no statistically significant differences between patients with cleft lip, unilateral cleft lip and palate and bilateral cleft lip and palate. The congenital absence of the cleft-side lateral incisor was observed in 40% of the sample, and a total of 30% patients showed supernumerary teeth at the incisors region. Second premolar agenesis was found in 4.4% of patients, whereas in 18.9% of the sample there was an ectopic dental eruption. Lateral or central incisors rotation was noted in 31.1% of the sample, while shape anomaly, lateral incisor microdontia, and enamel hypoplasia were detected respectively in 25.6%, 5.6% and 18.9% of cleft patients. CONCLUSION: High prevalence of different dental anomalies in children with cleft lip and unilateral and bilateral cleft lip and palate has been confirmed. This study, in particular, shows the presence of ectopic and rotated teeth in the cleft area.


Subject(s)
Cleft Lip/complications , Cleft Palate/complications , Tooth Abnormalities/epidemiology , Adolescent , Child , Child, Preschool , Female , Humans , Male , Prevalence , Tooth Abnormalities/complications , Young Adult
4.
Eur J Paediatr Dent ; 15(3): 293-6, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25306147

ABSTRACT

AIM: In this study, resonance and articulation disorders were examined in a group of patients surgically treated for cleft lip and palate, considering family social background, and children's ability of self monitoring their speech output while speaking. MATERIALS AND METHODS: Fifty children (32 males and 18 females) mean age 6.5 ± 1.6 years, affected by non-syndromic complete unilateral cleft of the lip and palate underwent the same surgical protocol. The speech level was evaluated using the Accordi's speech assessment protocol that focuses on intelligibility, nasality, nasal air escape, pharyngeal friction, and glottal stop. Pearson product-moment correlation analysis was used to detect significant associations between analysed parameters. RESULTS: A total of 16% (8 children) of the sample had severe to moderate degree of nasality and nasal air escape, presence of pharyngeal friction and glottal stop, which obviously compromise speech intelligibility. Ten children (10%) showed a barely acceptable phonological outcome: nasality and nasal air escape were mild to moderate, but the intelligibility remained poor. Thirty-two children (64%) had normal speech. Statistical analysis revealed a significant correlation between the severity of nasal resonance and nasal air escape (p ≤ 0.05). No statistical significant correlation was found between the final intelligibility and the patient social background, neither between the final intelligibility nor the age of the patients. CONCLUSION: The differences in speech outcome could be explained with a specific, subjective, and inborn ability, different for each child, in self-monitoring their speech output.


Subject(s)
Cleft Lip/surgery , Cleft Palate/surgery , Speech/physiology , Articulation Disorders/classification , Child , Child Language , Child, Preschool , Facial Muscles/physiology , Female , Humans , Male , Pharynx/physiology , Phonetics , Plastic Surgery Procedures/methods , Respiration , Speech Disorders/classification , Speech Intelligibility/physiology , Treatment Outcome , Voice Disorders/classification
5.
Int J Pediatr Otorhinolaryngol ; 73(5): 641-4, 2009 May.
Article in English | MEDLINE | ID: mdl-19181392

ABSTRACT

OBJECTIVE: Speech disorders could affect the intelligibility, but also social competence and emotional development of a cleft-palate child. In this study, we proposed to examine the phono-articulatory defects of a group of surgically treated cleft palate patients, relatively to the familial social background, and children ability of self-controlling during spontaneous language. METHODS: Sixty-eight children (22 males and 46 females) mean age 6.87 years, affected by a non-syndromic isolated cleft of the palate underwent to the same surgical protocol. Linguistic level was evaluated using the speech assessment protocol of Accordi and colleagues that focuses on intelligibility, nasality, nasal air escape, pharyngeal friction, and glottal stop. Each of these parameters is evaluated on a four-point scale, ranging from 0 to 3. Spearman rank order correlation was used to detect significant association between analyzed parameters; also the patient social background was considered for statistical analysis. RESULTS: The 5.88% of the sample had a negative result, with a severe to moderate degree of nasality and nasal air escape, presence of pharyngeal friction and glottal stop and, obviously a systematic compromising of the intelligibility. Also grimace was evident. The 38.23% of the sample showed an acceptable phonological outline; nasality and nasal air escape were mild, and the intelligibility resulted normal. Thirty-eight children (55.88%) showed a perfectly normal speech. Statistical analysis (Spearman rank order correlation) revealed a positive correlation between the severity of nasality and nasal air escape and the patient social contest of life (p

Subject(s)
Cleft Palate/epidemiology , Cleft Palate/surgery , Dysphonia/diagnosis , Dysphonia/epidemiology , Speech Disorders/diagnosis , Speech Disorders/epidemiology , Child , Female , Humans , Male , Phonetics , Postoperative Care , Preoperative Care , Severity of Illness Index , Speech Disorders/therapy , Speech Therapy
6.
Minerva Stomatol ; 56(1-2): 63-71, 2007.
Article in English | MEDLINE | ID: mdl-17287708

ABSTRACT

Bone grafting of the alveolus has become an essential part of the contemporary surgical management of oral clefts. The benefits of this procedure are the stabilization of the maxillary arch, elimination of oronasal fistulae, the reconstruction of the soft tissue nasal base support, creation of bony support for subsequent tooth eruption or, when they are not present or not preserved, for implants application. The authors show a case of bone grafting with the aid of platelet-rich plasma (PRP). Because of the difficulties due to the oral cleft and to its surgical reparation (big size of bone defect, hard scars and sclerotic soft tissue) the authors decided to add PRP to a bone graft taken from the chin. PRP contains a high concentration of growth factors and is able to stimulate both wound and bone regeneration. Infact, the authors have observed very good results both in bone integration and in soft tissue reparation.


Subject(s)
Alveoloplasty , Mandible/transplantation , Platelet-Rich Plasma , Tooth Socket/surgery , Transplantation, Autologous/methods , Adolescent , Anodontia/rehabilitation , Cleft Lip/rehabilitation , Cleft Lip/surgery , Cleft Palate/rehabilitation , Cleft Palate/surgery , Female , Gels , Humans , Incisor , Surgical Flaps , Thrombin/therapeutic use , Tooth Socket/abnormalities
7.
Minerva Stomatol ; 55(9): 483-92, 2006 Sep.
Article in English, Italian | MEDLINE | ID: mdl-17146427

ABSTRACT

AIM: Pleomorphic adenomas of salivary glands are benign lesions which may sometimes relapse even after complete surgical removal. This risk has led to the search for methods to provide predictive data on the biological behaviour of such neoplasia. The authors intend to evaluate the degree of cellular aggression of these tumours by finding prognostic data using the antigens involved in cellular proliferative activity. Therefore they have chosen for this study: p27kip1, cyclin B1 and Cyclin D3. METHODS: Seventeen mixed tumours, 2 of them relapsed, underwent the direct immunohystochemical PAP technique for the determination of antigens p27kip1, cyclins B1 and D3 of the tissue. RESULTS: The results obtained show that the verification of these markers may reveal a potential risk of biological deviation and that their expression is independent of the degree of cellularity in neoplasias. CONCLUSIONS: On the basis of the results, the conclusion is drawn that there is no relation between the expressivity of the mentioned antigens and histological characters of pleomorphic adenomas.


Subject(s)
Adenoma, Pleomorphic/chemistry , Biomarkers, Tumor/analysis , Cyclin B/analysis , Cyclin-Dependent Kinase Inhibitor p27/analysis , Cyclins/analysis , Salivary Gland Neoplasms/chemistry , Adenoma, Pleomorphic/pathology , Adolescent , Adult , Aged , Biomarkers, Tumor/immunology , Cyclin B/immunology , Cyclin B1 , Cyclin D3 , Cyclin-Dependent Kinase Inhibitor p27/immunology , Cyclins/immunology , Humans , Immunohistochemistry/methods , Middle Aged , Prognosis , Salivary Gland Neoplasms/pathology
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