Subject(s)
Colitis, Ischemic/etiology , Protein S Deficiency/complications , Adult , Female , HumansSubject(s)
Ascites/etiology , Crohn Disease/complications , Adult , Crohn Disease/diagnosis , Female , HumansSubject(s)
Colonic Neoplasms/prevention & control , Colonic Polyps/prevention & control , Colonoscopy/methods , Colorectal Neoplasms/genetics , Adult , Colonic Neoplasms/genetics , Colonic Polyps/genetics , Female , Humans , Male , Mass Screening , Middle Aged , Prospective Studies , Retrospective StudiesSubject(s)
Angiodysplasia/surgery , Duodenal Diseases/surgery , Kidney Failure, Chronic/therapy , Laser Therapy/methods , Stomach Diseases/surgery , Angiodysplasia/etiology , Colonic Diseases/etiology , Colonic Diseases/surgery , Duodenal Diseases/etiology , Female , Follow-Up Studies , Humans , Kidney Failure, Chronic/complications , Male , Middle Aged , Renal Dialysis , Retrospective Studies , Stomach Diseases/etiologySubject(s)
Colonic Neoplasms/diagnosis , Colonic Polyps/diagnosis , Colonoscopy/methods , Occult Blood , Aged , Humans , Male , Middle AgedABSTRACT
The mucin profile of 24 endoscopic biopsies of heterotopic gastric mucosa (HGM) of the upper esophagus in adults and a control group of ten cases of Meckel's diverticula containing heterotopic gastric mucosa were studied with two combined histochemical methods: alcian blue pH 2.5/PAS and high iron diamine/alcian blue pH 2.5. The clinical and light microscopic features of the 24 HGM cases were also reviewed. In addition to overall secretion of neutral mucins by the 24 HGM cases, mucin histochemistry showed prominent secretion of acidic mucins in 19 of 24 HGM cases (79%), with sulphomucins in 11 of 24 HGM cases (45.8%). This mucin profile of HGM was unlike that of either normal gastric mucosa or heterotopic gastric mucosa in Meckel's diverticula. Moreover, a comparison between the mucin profile and clinical features of HGM and Barrett's esophagus showed certain similarities. The data suggest a physiopathologic link between HGM and Barrett's esophagus.
Subject(s)
Choristoma/pathology , Esophageal Neoplasms/pathology , Gastric Mucosa , Adolescent , Adult , Aged , Aged, 80 and over , Barrett Esophagus/pathology , Choristoma/analysis , Esophageal Neoplasms/analysis , Female , Gastric Mucosa/pathology , Humans , Male , Middle Aged , Mucins/analysisSubject(s)
Choristoma/pathology , Esophageal Neoplasms/pathology , Stomach , Adult , Aged , Esophagoscopy , Female , Humans , Male , Middle AgedABSTRACT
A patient is reported with chronic abdominal pain, diarrhoea, and associated radiological and endoscopic abnormalities of the sigmoid colon. Light and electron microscopic study of colorectal mucosa showed abnormal collagenous thickening of the subepithelial basement membrane. The authors felt that the clinical and morphological features justified a diagnosis of collagenous colitis. Review of the literature suggested that collagenous colitis was still an unrecognised entity.
