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1.
Rev Sci Instrum ; 95(4)2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38629926

ABSTRACT

This work addresses discrepancies in the alignment of the H-mode pedestal profiles of the electron and ion properties in the DIII-D tokamak as measured by Thomson Scattering (TS) and Charge Exchange Recombination Spectroscopy (CER) diagnostics. While the alignment of these profiles is key for accurate studies of tokamak physics and plasma confinement, misalignments can occur due to inaccuracies, such as in magnetic equilibrium reconstructions required to map measurements in different poloidal and toroidal locations. Both FIDASIM, an established simulation package, and a simplified collisional radiative model are used to simulate neutral beam state densities and neutral beam emission. Simulated neutral beam emissions are calculated based on shifted TS profiles and compared to beam emission measurements from the Main Ion CER system to determine the best shift for aligning TS with CER. This analysis is performed on various DIII-D discharges.

2.
Neurosci Lett ; 51(3): 331-5, 1984 Oct 26.
Article in English | MEDLINE | ID: mdl-6521960

ABSTRACT

Thin bundles dissected from mouse soleus muscles were kept in culture media containing 10% calf serum. After 3 days of culture at 37 degrees C the muscles were tested for acetylcholine (ACh) sensitivity by measuring the force of the contracture produced by 10 microM ACh. The ACh-receptor density was measured by the [125I]alpha-bungarotoxin method. When the [Ca2+] of the culture medium was 0.02 mM (instead of the normal 2 mM), ACh sensitivity and ACh-receptor density were not different from control. Replacement of 99% Ca2+ by Sr2+ or by Mg2+ was also without effect. The muscles did not survive in solutions containing Ni ions. ACh sensitivity and ACh-receptor density were at levels characteristic of non-cultured muscles when the culture medium contained 0.4-1.8 mM Mn2+. Since the incorporation of ACh receptors into the membrane was not affected by Mn ions these results indicate that Mn ions inhibit the synthesis of ACh receptors.


Subject(s)
Manganese/pharmacology , Muscles/metabolism , Receptors, Cholinergic/biosynthesis , Acetylcholine/pharmacology , Animals , Depression, Chemical , Female , Magnesium/pharmacology , Male , Manganese/metabolism , Mice , Muscle Denervation , Strontium/pharmacology
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