Subject(s)
Erectile Dysfunction/etiology , Natural Orifice Endoscopic Surgery/methods , Postoperative Complications , Urethra/surgery , Urethral Stricture/surgery , Anastomosis, Surgical/adverse effects , Dilatation , Endoscopy/methods , Humans , Male , Natural Orifice Endoscopic Surgery/adverse effects , Priapism/etiologyABSTRACT
The main goals for urinary stone treatment are to preserve renal function, reduce or avoid complications related to calculi, and to render the patient free of calculi as soon as possible. Anatrophic nephrolithotomy (ANL) is a valid and useful alternative for conventional staghorn calculi excision. Although excellent stone free rates can be achieved with ANL there are some drawbacks that may be of concern. Morbidity related to intraoperative and postoperative complications is one of them. Another, great concern is the possibility of reduction on renal function related to the procedure itself. This may be related to nephron injury during nephrotomy and parenchymal closure or to ischemic injury. In this review we assess functional results after anatrophic nephrolithotomy.
ABSTRACT
A pancreatite crônica hereditária é definida como uma doença autossômica dominante rara caracterizada porepisódios recorrentes de pancreatite aguda em dois ou mais membros de várias gerações da família. A maioriados pacientes possui mutações nos genes PRSS1, SPINK1 ou CFTR. Relata-se o caso de uma paciente com um quadro agudo de pancreatite secundário a um processo crônico calcificado subjacente, em que na investigação familiar seis membros já haviamapresentado episódios de pancreatite. A pesquisa das alterações genéticas características não foi possível porlimitações do serviço.
Chronic hereditary pancreatitis is defined as a rare autossomic dominant disease, characterized by recurrentepisodes of acute pancreattis in two or more members of several familiar generations. Most of these patientspresent mutation on genes PRSS1, SPINK1 or CFTR. Its reported the case of a patient with an acute episodeof pancreatitis secondary to a chronic calcified underlying process, in which six cases of history of previous episodesof pancreatitis were found, through familiar investigation. The screening for genetic alterations was not possibledue to the lack of resources of the heath care service.
Subject(s)
Humans , Female , Adult , Genetic Diseases, Inborn , Pancreatitis, Chronic/diagnosis , Pancreatitis, Chronic/complications , Pancreatitis, Chronic/congenital , Pancreatitis, Chronic/metabolism , Pancreatitis, Chronic/pathologyABSTRACT
OBJECTIVE: To study the effects of hyperbaric oxygen therapy on tissue lesions in an experimental model of acute pancreatitis induced by pancreatic duct ligation. ANIMALS: Forty-eight adult female Wistar rats were randomized into two groups (n=24): control group and hyperbaric oxygen therapy group. INTERVENTION: The second group was treated with a two-hour daily session of hyperbaric oxygen therapy at 2.5 ATA started 6 hours after pancreatic duct ligation. SETTING: The two groups were divided into 3 subgroups of 8 rats each undergoing euthanasia on days 1, 3, and 7 after the acute pancreatitis induction. MAIN OUTCOME MEASURES: The pancreas was evaluated according to the following histopathologic criteria: edema, hemorrhage, acinar necrosis and leukocyte infiltration. RESULTS: Hyperbaric oxygen therapy was efficient in significantly reducing acinar necrosis on the first day (P=0.049) and the foci of hemorrhage on the seventh day (P=0.050). The edema and leukocyte infiltration did not show the expected reduction. CONCLUSION: The utilization of a daily session of hyperbaric oxygen therapy at 2.5 ATA is efficient in reducing the hemorrhage and acinar necrosis but is not sufficient to reduce edema and leukocyte infiltration.
Subject(s)
Hyperbaric Oxygenation , Pancreatitis/therapy , Acute Disease , Amylases/metabolism , Animals , Disease Models, Animal , Female , Hemorrhage/diagnosis , Necrosis/diagnosis , Pancreatitis/metabolism , Pancreatitis/pathology , Rats , Rats, Wistar , Research DesignABSTRACT
A infertilidade masculina induzida por medicamentos pode ser uma consequência indesejada de um tratamento clínico e, também, do uso de suplementos dietéticos ou de drogas ilícitas. Casos como esses podem ser minimizados quando o clínico tem conhecimento, ao receitar algum medicamento, das possíveis alterações na fertilidade de seus pacientes. Diante disso, uma história clínica completa, incluindo um interrogatório minucioso quanto ao uso de medicações e suplementos deve ser realizada nesses pacientes.
