ABSTRACT
The association of speech and language disorders with epilepsy is well-known in children with acquired epileptic aphasia, involving such entities as Landau-Kleffner syndrome (LKS), continuous spike wave in slow wave sleep (CSWSS) epilepsy and benign partial epilepsy with centro-temporal spikes (BPECTS). The possible association between epilepsy and a subgroup of children with developmental dysphasia is reported less frequently. Lack of controlled prospective studies of sleep electroencephalograms (EEG), and the use of medication, in children with developmental dysphasia, may deny appropriate treatment strategies to children with severe developmental speech and language disorders.
Subject(s)
Epilepsy/complications , Language Development Disorders/etiology , Child , Child, Preschool , Clinical Trials as Topic , Diagnosis, Differential , Electroencephalography , Epilepsy/physiopathology , Humans , Landau-Kleffner Syndrome/complications , Landau-Kleffner Syndrome/physiopathology , Language Development Disorders/physiopathology , PrognosisABSTRACT
This is the first published report of Landau-Kleffner syndrome occurring discordantly in monozygotic twins. The implications of this finding in the understanding of the etiology of this condition are discussed. Five other patients are reported and comparisons are drawn with other series.
