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Antimicrob Agents Chemother ; 57(1): 651-4, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23147737

ABSTRACT

Resistance to minocycline has emerged in multidrug-resistant Acinetobacter baumannii isolates from Buenos Aires hospitals. Few reports about the description and dispersion of tet genes in this species have been published. We observed the presence of tet(B) in all minocycline-resistant isolates. This gene was found to be associated with the ISCR2 mobile element, which may, in part, explain its dispersion.


Subject(s)
Acinetobacter Infections/microbiology , Acinetobacter baumannii/genetics , Anti-Bacterial Agents/therapeutic use , Minocycline/therapeutic use , Plasmids , Tetracycline Resistance/genetics , Acinetobacter Infections/drug therapy , Acinetobacter Infections/epidemiology , Acinetobacter baumannii/isolation & purification , Anti-Bacterial Agents/pharmacology , Argentina/epidemiology , Base Sequence , Humans , Microbial Sensitivity Tests , Minocycline/pharmacology , Molecular Sequence Data , Retroelements , Sequence Analysis, DNA
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