ABSTRACT
Diagnostics of those or other pathological processes is connected with an estimation of deviations of corresponding laboratory indexes from their reference values. Results of the research enable to use the indexes of individual variability of laboratory tests as a criterion of individual resistance, which has a prognosis value in studying of age pathology. It also essentially expands ideas about activation of the peroxide oxidation of the lipids as the basic trigger factor of the accelerated aging.
Subject(s)
Aging, Premature/blood , Radiation Injuries, Experimental/complications , Aging, Premature/etiology , Aging, Premature/metabolism , Animals , Humans , Leukocyte Count , Leukocytes/cytology , Leukocytes/radiation effects , Lipid Peroxidation/radiation effects , Lipids/blood , Lymphocytes/cytology , Lymphocytes/radiation effects , Male , Predictive Value of Tests , Radiation Tolerance/physiology , Rats , Severity of Illness IndexABSTRACT
Lung transplantation is one of the most difficult fields of contemporary transplantology. The operation was performed on a 53-year-old female who had been suffering from terminal stage COPD. The period of cold ischemia for the right and left lung was 1 hour 30 minutes and 2 hours 25 minutes respectively. The total operation time was 4 hours and 40 minutes. There were no surgical complications. There were no signs of transplant rejection 6 weeks after the operation. The considerable decrease in dispnea and increase in quality of life were registered during the follow-up. FEV1 was increased by 80% and 6 minute walk test distance was increased by 200 meters.
