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4.
Klin Med (Mosk) ; 85(5): 71-2, 2007.
Article in Russian | MEDLINE | ID: mdl-17665611

ABSTRACT

The authors adduce a brief description of the features and outcomes of hemorrhagic fever with renal syndrome (HFRS) in 8 pregnant women. The results of the examination of a 54-year-old woman and her son, who suffered from a severe form of HERS 28 years ago during the 31st week of pregnancy, are presented in detail. Antibodies to Hantaan virus 1:32 were found; magnetic resonance tomography of the skull revealed sequelae of hypophysial hemorrhage with the formation of "partly empty ephippium". The antibodies were not found in the son; hydrocephalus, forehead cortex atrophy, and lateral ventricular asymmetry were revealed.


Subject(s)
Antibodies, Viral/blood , Brain Diseases/virology , Hantaan virus/isolation & purification , Hemorrhagic Fever with Renal Syndrome/complications , Pregnancy Complications, Infectious/virology , Adult , Atrophy/virology , Cerebral Hemorrhage/etiology , Cerebral Ventricles/pathology , Female , Frontal Lobe/pathology , Hantaan virus/immunology , Humans , Hydrocephalus/virology , Middle Aged , Pituitary Diseases/complications , Pituitary Diseases/virology , Pregnancy , Pregnancy Trimester, Third
5.
Klin Med (Mosk) ; 85(4): 58-9, 2007.
Article in Russian | MEDLINE | ID: mdl-17564042

ABSTRACT

The authors describe two lethal outcomes of severe hemorrhagic fever with renal syndrome in spouses aged 50 and 44. A detailed description of clinical symptoms, the results of laboratory and instrumental tests, and possible mechanisms of contamination is given. Cross-sectional photographs of kidneys and hypophyseal hemorrhage, as well as radiograms of renal arteries and right pulmonary blood vessels after post-mortem filling with radiopaque mass are presented.


Subject(s)
Hemorrhagic Fever with Renal Syndrome/genetics , Hemorrhagic Fever with Renal Syndrome/physiopathology , Anti-Bacterial Agents/therapeutic use , Fatal Outcome , Hemorrhagic Fever with Renal Syndrome/drug therapy , Humans , Male , Middle Aged , Severity of Illness Index
15.
Zh Mikrobiol Epidemiol Immunobiol ; (3): 48-52, 1990 Mar.
Article in Russian | MEDLINE | ID: mdl-1973327

ABSTRACT

To carry out serodiagnosis and to determine the serotype of the virus causing hemorrhagic fever with the renal syndrome (HFRS), paired sera obtained from 28 HFRS patients, 42 persons with a history of HFRS (1-17 years after convalescence), and 268 serum samples from healthy persons residing at the areas with the natural foci of this infection have been studied by indirect immunofluorescence techniques at the territory of the Amur Province. This study has demonstrated for the first time that, alongside the diseases caused by HFRS virus of serotype Apodemus, HFRS viruses of serotype Rattus and an unidentified serotype serve as the source of infection for the population of the Amur region. The leading role of serotype Rattus in HFRS has been confirmed by the detection of antibodies mainly to this serotype in serum samples taken from convalescents after HFRS and from the healthy population of the areas with the foci of HFRS virus infection.


Subject(s)
Hemorrhagic Fever with Renal Syndrome/microbiology , Orthohantavirus/classification , Rodentia/microbiology , Animals , Antibodies, Viral/analysis , Arvicolinae/microbiology , Convalescence , Orthohantavirus/immunology , Hemorrhagic Fever with Renal Syndrome/epidemiology , Hemorrhagic Fever with Renal Syndrome/immunology , Humans , Muridae/microbiology , Rats , Seroepidemiologic Studies , Serotyping , Siberia/epidemiology
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