[Alpha-fetoprotein in acute viral hepatitis type A]. / Alfa-fetoproteina w ostrym wirusowym zapaleniu watroby typu A.

Serum AFP levels were estimated by radioimmunoassay (RIA) at the first and the last but one day of hospitalization of 25 patients with acute viral hepatitis of type A. The observed group consisted of 11 women and 9 men. A significant increase in the serum AFP levels was found in the group of patients on the first day of hospitalization. Besides, a rise in the aminotransferases (ALT and AST) activity and in the serum total bilirubin level were observed. On the last but one day of hospitalization the mean value of serum AFP level and the activity of the investigated enzymes were diminished. Mean value of serum AFP level the and activity of aminotransferases were higher in patients than those in the control group. Only serum total bilirubin level was similar to the mean value of control group.

[Level of prolactin, gonadotrophin, testosterone, and alpha fetoprotein in serum of blood donors with antibodies to hepatitis c virus (anti-HCV)]. / Poziom prolaktyny, gonadotropin, testosteronu i alfa-fetoproteiny w surowicy krwi krwiodawców, nosicieli przeciwcial przeciwko wirusowemu zapaleniu watroby typu-C (anty-HCV).

The study was aimed at the determination of serum levels of the investigated hormones (prolactin, gonadotrophins, testosterone and alpha-fetoprotein) in blood donors with antibodies to hepatitis C virus. The observed group consisted of 50 men of age between 22 and 47 years. The blood serum concentrations of hormones were determined by RIA method using the ready made reagent kits. No characteristic changes were observed in the serum hormones levels except for prolactin. Mean value of serum prolactin concentration was higher in blood donors than those in the control group.