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Patol Fiziol Eksp Ter ; (5-6): 41-3, 1992.
Article in Russian | MEDLINE | ID: mdl-1284611

ABSTRACT

The authors studied luminol-dependent chemiluminescence of rabbit peripheral blood leukocytes during the development of Arthus' phenomenon. Samples with a specific allergen were previously incubated. It was established that in this type of allergic reactions the intensity of leukocyte chemiluminescence was determined by the concentration of the allergen with which they were incubated. Small doses of the allergen stimulate and large doses inhibit it. The inhibition is linked with the direct effect of the allergen on the cells and is not attended with diminution of their viability.


Subject(s)
Arthus Reaction/blood , Luminol/pharmacology , Neutrophils/drug effects , Allergens/immunology , Animals , Arthus Reaction/immunology , Epitopes , Luminescent Measurements , Neutrophils/chemistry , Neutrophils/immunology , Rabbits
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