Subject(s)
Antihypertensive Agents/administration & dosage , Brain Infarction/drug therapy , Diabetes Mellitus, Type 2/complications , Hypertension/complications , Vinca Alkaloids/administration & dosage , Administration, Oral , Blood Flow Velocity , Blood Pressure/drug effects , Brain Infarction/diagnosis , Brain Infarction/etiology , Cerebrovascular Circulation/drug effects , Cerebrovascular Circulation/physiology , Diabetes Mellitus, Type 2/physiopathology , Drug Administration Schedule , Female , Humans , Hypertension/physiopathology , Infusions, Intravenous , Male , Middle Aged , Treatment Outcome , Ultrasonography, Doppler, TranscranialABSTRACT
Investigations of etiology, pathogenesis and treatment of polypous ethmoiditis show the role of chronic inflammation, sensitization and autoimmune reactions in mechanisms of nasal polyposis (NP). The development of postoperative recurrences of NP depends on the microflora, defective microcirculation, permeability of the histohematic barriers of the nasal and labyrinthine mucosa and metabolism of glycosaminoglycanes in the above mucosa. Adequate treatment methods are suggested: He-Ne laser radiation, UV blood radiation, cryotherapy, corticosteroids. Promising are also autovaccine, autovaccine with tissue (polypous) antigen, ozone solutions.
Subject(s)
Ethmoid Sinusitis , Nasal Polyps , Chronic Disease , Ethmoid Sinusitis/complications , Ethmoid Sinusitis/etiology , Ethmoid Sinusitis/therapy , Humans , Nasal Polyps/complications , Nasal Polyps/etiology , Nasal Polyps/therapy , Secondary PreventionABSTRACT
The paper reviews clinical, morphological, immunological and biochemical effects on acute and chronic inflammation in the upper airways and the ear produced by the exposure to cryoeffects, He-Ne or infrared laser radiation, ultraviolet blood radiation. The original advanced procedures developed by the author seem superior to conventional approaches to diagnosis and treatment of ENT inflammation.
Subject(s)
Inflammation/therapy , Otorhinolaryngologic Diseases/therapy , Physical Therapy Modalities , Acute Disease , Chronic Disease , Combined Modality Therapy , Cryotherapy , Inflammation/immunology , Inflammation/physiopathology , Infrared Rays/therapeutic use , Laser Therapy , Otorhinolaryngologic Diseases/immunology , Otorhinolaryngologic Diseases/physiopathology , Ultraviolet TherapyABSTRACT
During surgical elimination of external nose deformation biologically inert prostheses were used. In the post-operative period low-intensity laser therapy was applied. No adverse effects of corundum ceramics were noted. The procedure of posterior tamponade was modified to ensure complete isolation of the nasopharynx during surgical manipulations on the external nose skeleton.
Subject(s)
Ceramics , Nose Deformities, Acquired/surgery , Nose/abnormalities , Prostheses and Implants , Rhinoplasty/methods , Adolescent , Adult , Female , Humans , Male , Middle Aged , Nose/surgery , Postoperative Care , Prosthesis Design , Rhinoplasty/instrumentation , USSRABSTRACT
Therapeutic effect of liposomal dosages of rifampicin and prodigiozan was studied on rabbits with simulated chronic tonsillitis in comparison to that of commercial ones of the drugs. The treatment schemes included daily intra-tonsillar++ injections of the dosage forms for 5 days. A high efficacy of their liposomal dosage forms in treatment of experimental chronic tonsillitis was confirmed microbiologically and immunologically. Approval of the liposomal dosage forms used in the therapy of patients with chronic tonsillitis requires clinical trials.
Subject(s)
Polysaccharides, Bacterial/administration & dosage , Prodigiozan/administration & dosage , Rifampin/administration & dosage , Streptococcal Infections/drug therapy , Tonsillitis/drug therapy , Adjuvants, Immunologic , Animals , Chronic Disease , Drug Carriers , Drug Evaluation, Preclinical , Drug Therapy, Combination , Liposomes , Palatine Tonsil/drug effects , Palatine Tonsil/immunology , Rabbits , Streptococcal Infections/immunology , Tonsillitis/immunologyABSTRACT
Clinical and immunological examinations of 360 patients with chronic tonsillitis and 286 patients suffering from systemic complications of chronic tonsillitis at various post-tonsillectomy stages demonstrated that the major immunopathological factor in the case of chronic compensated tonsillitis was microbial allergy and in the case of chronic decompensated tonsillitis, autoimmune disorders. The high titer of autoantibodies to tonsillar antigen that persisted at various post-tonsillectomy stages made it necessary to use systemic immune correction as part of therapy of chronic tonsillitis.
