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Semin Cell Dev Biol
; 144: 3-10, 2023 07 30.
Article
in English
| MEDLINE
| ID: mdl-36192310
ABSTRACT
Organoid development and organ-on-a-chip are technologies based on differentiating stem cells, forming 3D multicellular structures resembling organs and tissues in vivo. Hence, both can be strategically used for disease modeling, drug screening, and host-pathogen studies. In this context, this review highlights the significant advancements in the area, providing technical approaches to organoids and organ-on-a-chip that best imitate in vivo physiology.