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1.
Phys Med Biol ; 69(6)2024 Mar 12.
Article in English | MEDLINE | ID: mdl-38359454

ABSTRACT

Background.Proton arc therapy (PAT) is an emerging radiation therapy technique where either the gantry or the patient continuously rotates during the irradiation treatment. One of the perceived advantages of PAT is the reduced treatment time, but it is still unclear exactly how long these treatment times will be, given that no machine capable of its delivery is available on the market at the time of writing.Objective.We introduce the algorithm arc trajectory optimization method (ATOM), which aims to determine an efficient velocity profile for the gantry for rapid delivery of a given proton arc treatment plan. This algorithm could be used to minimize the delivery time of a proton arc plan without changing the plan or updating the machine.Approach.ATOM computes the trajectory with the shortest delivery time while ensuring there is enough time to deliver all spots in each energy layer and switch energy between layers. The feasibility of the dynamic gantry movement was assured by enforcing maximum and minimum limits for velocity, acceleration, and jerk. This was achieved by discretizing the gantry velocity and combining theA* algorithm with the open-source motion generation library Ruckig. The algorithm was tested on a synthetic data set as well as a liver case, a prostate case and a head and neck case.Main results.Arc trajectories for plans with 360 energy layers were calculated in under a second using 256 discrete velocities. The delivery time of the liver case, the prostate case and the head and neck case were 284 s, 288 s and 309 s respectively, for 180 energy layers.Significance.ATOM is an open-source C++ library with a Python interface that rapidly generates velocity profiles, making it a highly efficient tool for determining proton arc delivery times, which could be integrated into the treatment planning process.


Subject(s)
Proton Therapy , Radiotherapy, Intensity-Modulated , Male , Humans , Protons , Radiotherapy Dosage , Radiotherapy, Intensity-Modulated/methods , Radiotherapy Planning, Computer-Assisted/methods , Proton Therapy/methods
2.
Water Sci Technol ; 76(3-4): 869-876, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28799933

ABSTRACT

In 2014, 25% of the sludge produced at Swedish municipal wastewater treatment plants was applied to agricultural land. Even though the Swedish heavy metal limits for sludge to be used in agriculture are amongst the most stringent in the EU, more stringent heavy metal limits are proposed. Most sludge applied to agricultural land is recycled within a certification system, Revaq. Revaq has targets for control at source management and improvement of sludge quality. Statistics based on data collected within the Revaq system was used to differentiate between local and general sources of heavy metals and assess the need to improve sludge quality. The analysis indicates that proposed future national limits on the quality of the sludge can be met by most of the sludge. The improvement needed for about 20% of the sludge is feasible through local control at source management. The levels of cadmium, copper and mercury need to be reduced if these metals are not to limit the amount of sludge that may be applied per unit area of arable land. Finally, the long term Revaq targets for cadmium and silver will be difficult to meet.


Subject(s)
Metals, Heavy/chemistry , Sewage/chemistry , Agriculture , Cities , Environmental Monitoring , Recycling , Sweden , Wastewater/analysis
3.
Water Sci Technol ; 75(9-10): 2013-2024, 2017 May.
Article in English | MEDLINE | ID: mdl-28498114

ABSTRACT

To provide input to sewage sludge management strategies that address expected new regulations in terms of hygienisation and phosphorus recovery in Sweden, an environmental life cycle assessment (LCA) was made. The LCA identified environmental hot spots for methods that may permit sludge or phosphorus from sludge to be applied on agricultural land. In particular, thermophilic digestion, pasteurisation, thermal hydrolysis, urea treatment and mono-incineration with phosphorus recovery were compared. In addition, a sludge management system involving drying of sludge before use in forestry was investigated. The results showed that some major impacts are related to large uncertainties, such as those related to emissions from sludge storage. It also showed that large gains can be achieved when products from the systems replace other products, in particular when biogas is used to replace natural gas in vehicles, but also when sludge is used in agriculture and forestry. In general, there are small differences between the sludge management methods. Retaining the sludge matrix to allow for its utilisation in agriculture may conflict with keeping emissions to air and water from the sludge matrix low. It is recommended that any sludge management option minimises emissions from sludge to air and water and that resources are recovered and used, in line with the principles of a circular economy.


Subject(s)
Phosphorus/chemistry , Sewage/chemistry , Waste Disposal, Fluid/methods , Agriculture , Biofuels , Environment , Hydrolysis , Incineration , Sweden , Water Pollutants, Chemical
4.
J Food Prot ; 67(11): 2570-7, 2004 Nov.
Article in English | MEDLINE | ID: mdl-15553644

ABSTRACT

The lack of data on consumer refrigeration temperatures and storage times limits our ability to assess and manage risks associated with microbial hazards. This study addressed these limitations by collecting data on temperatures and storage handling practices of chilled foods. Consumers from 102 households in Uppsala, Sweden, were instructed to purchase seven food items (minced meat, fresh herring fillets, soft cheese, milk, sliced cooked ham, vacuum-packed smoked salmon, and ready-to-eat salad) and to store them using their normal practices. They were interviewed the next day, and food temperatures were measured. In general, there were no significant relations between temperature and characteristics of the respondents (e.g., sex, age, education, age of the refrigerator). Mean storage temperatures ranged from 6.2 degrees C for minced meat to 7.4 degrees C for ready-to-eat salad. Maximum temperatures ranged from 11.3 to 18.2 degrees C. Data were not significantly different from a normal distribution, except for ready-to-eat salad, although distributions other than the normal fitted data better in most cases. Five percent to 20% of the food items were stored at temperatures above 10 degrees C. Most respondents knew the recommended maximum temperature, but less than one fourth claimed to know the temperature in their own refrigerator. Practical considerations usually determined where food was stored. For products with a long shelf life, stated storage times were different for opened and unopened packages. The current situation might be improved if consumers could be persuaded to use a thermometer to keep track of refrigerator temperature.


Subject(s)
Consumer Product Safety , Food Handling/methods , Health Knowledge, Attitudes, Practice , Refrigeration/standards , Adult , Analysis of Variance , Data Collection , Female , Food Microbiology , Humans , Male , Surveys and Questionnaires , Sweden , Temperature , Time Factors
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