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1.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 1-7, 2020.
Article in English | MEDLINE | ID: mdl-33541060

ABSTRACT

Sander bite jumping appliance (BJA) is a functional appliance used to correct Class II malocclusion in growing patients. The aim of this study was to identify the dento-skeletal effects in patients treated with BJA before growth peak and to compare these effects with the ones obtained in a similar group treated with the Andresen activator (AA). Twenty subjects with class II relationship of the skeletal bases and cervical vertebrae maturation stage 1 or 2 were enrolled in the study and treated with BJA. This group were compared to 14 subjects treated with AA. Cephalometric analyses were carried out using landmarks derived from the analyses of Pancherz, Ricketts, Tweed and Steiner. After treatment with BJA Pg/OLp increase was 7.40±3.81 mm (P<0.001); Pg/OLp+Co/OLp significantly heightened from T0 to T1 (T0: 82.20±4.65 mm vs T1: 89.62±4.27, P<0.001). Overjet (is/OLp - ii/OLp) significantly decreased from T0 to T1 (T0: 7.40±2.31 mm vs T1: 3.05±1.34 mm, P<0.001). Molar relationship improved passing from 1.46±1.68 mm at T0 to -3.56±2.04 mm at T1 (P<0.001). No statistically significant differences were found between BJA and AA groups at T0 and T1. BJA treatment determined a Class II malocclusion correction in all patients. The correction of molar relationship was mainly due to the increase in mandibular length; the correction of the overjet was due to the increase in mandibular length, to the slight pro-inclination of the lower incisors and the mild retro-inclination of the upper incisors. No significant differences were found in effectiveness between BJA and AA.


Subject(s)
Malocclusion, Angle Class II/therapy , Cephalometry , Humans , Incisor , Mandible
2.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 9-20, 2020.
Article in English | MEDLINE | ID: mdl-33541061

ABSTRACT

The atrophic posterior ridges are usually characterized by poor bone quality and quantity: this situation requires the use of bone regenerative techniques. Other alternative surgical approaches are investigated. Nowadays the use of trans-sinus implants offers some advantages due to its feasibility. Today, bone grafting may be practical, but depends on many factors, such as the type of bone graft used (autogenous, alloplastic, or xenograft), host response, age of the patient, various complications associated with grafting procedures, infection, and, most importantly, the time spent while the grafted material matures and is taken up by the bone. So, this case report describes the feasibility of an alternative surgical technique associated to PRP (Platelet Rich Plasma).


Subject(s)
Dental Implants , Maxilla/surgery , Maxillary Sinus/surgery , Platelet-Rich Plasma , Bone Regeneration , Bone Transplantation , Humans
3.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 37-48, 2020.
Article in English | MEDLINE | ID: mdl-33541063

ABSTRACT

Medication-related osteonecrosis of the jaw (MRONJ) is a major disease under study for over the last twenty years. Different classifications have been proposed and many therapies for the different stages have been applied. The evolution of treatments lead to an increasingly conservative approach. Numerous adjuvant treatments have been proposed in the last decade. All these complementary treatments have been proposed mainly to resolve or reduce the painful stress, predominantly caused by bacterial infection, simplifying the wound healing process and improving patients' compliance. Nowadays "secondary" treatments, such as autologous platelet concentrates (APCs, more specifically PRP, PRGF or PRF), hyperbaric oxygen (HBO), Auto/tetracycline fluorescence-guided bone surgery (AF-GBS/TF-GBS), medical drugs like teriparatide or the combination between pentoxifylline and tocopherol, fluorodeoxyglucose positron emission tomography (FDG-PET), laser and/or low-laser therapy and ozone therapy are more or less well documented and known considering their clinical effectiveness. The aim of the present review is the evaluation of the quantity and quality of scientific studies concerning this specific topic.


Subject(s)
Bisphosphonate-Associated Osteonecrosis of the Jaw/diagnosis , Bisphosphonate-Associated Osteonecrosis of the Jaw/therapy , Anti-Bacterial Agents/therapeutic use , Bone Density Conservation Agents/adverse effects , Diphosphonates/adverse effects , Humans , Laser Therapy , Tocopherols/therapeutic use , Treatment Outcome
4.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 49-61, 2020.
Article in English | MEDLINE | ID: mdl-33541064

ABSTRACT

The introduction of computer-assisted and guided surgery has radically improved the possibility of using all available bone for implant support, reducing the need for extensive grafting procedures and allowing for better implant placement and restoration. Moreover, fresh frozen homologous bone (FFB) grafts have shown good osteoconductive properties and biocompatibility with results comparable to autologous bone patients. The purpose of this retrospective cohort study was to evaluate the survival and the success rate of implants and related fixed full arch prosthesis at the 5 to 8 years follow-up when performed with immediate function using a flapless surgical procedure and computer-aided technology (NobelGuide®, Nobel Biocare® AB, Goteborg, Sweden) in patients previously treated with FFB grafts; treated at the University of Verona with the NobelGuide® system from January 2007 to December 2012 with at least 5 years follow-up were reviewed. Survival implants and survival prosthesis' percentage reached 95% in a 5 to 8-year period. This study indicates that patients previously augmented with FFB graft for maxillary or mandibular bone atrophy can be safely treated with implant supported prosthesis based on the NobelGuide® protocol, with the aid of computer-generated guide.


Subject(s)
Dental Implants , Surgery, Computer-Assisted , Follow-Up Studies , Humans , Retrospective Studies , Sweden , Treatment Outcome
5.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 63-68, 2020.
Article in English | MEDLINE | ID: mdl-33541065

ABSTRACT

The infant, like the young un-cooperative or odontophobic patient, constitute the most complex type of patient to be treated and it is frequent in modern society. The treatment of these patients is necessary to resolve the infectious-antalgic urgency and subsequently to build the patient/doctor relationship for continuing general dental care. Conscious sedation is the only way to approach this type of patient. Where therapeutic success with traditional sedation techniques is not achieved, as frequently happens in these patients, sedation with ketamine is the extreme ratio for the purpose of effective resolution of the dental problem, obviously carried out within facilities authorized for these anesthesiological modalities such as private outpatient surgery structures where, when necessary, it is possible to carry out the treatments also under general anesthesia as well as with ketamine.


Subject(s)
Anesthesia, Dental/methods , Dentistry/methods , Ketamine/therapeutic use , Anesthesia, General , Child , Conscious Sedation , Humans , Infant
6.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 69-76, 2020.
Article in English | MEDLINE | ID: mdl-33541066

ABSTRACT

Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) is a pathology initially described in the early 2000s that has become increasingly common in clinical dentistry and maxillofacial practice due to the frequent use of bisphosphonates medical drugs (BPs) to treat various diseases such as osteoporosis, Paget's syndrome, osteomyelitis and in bone metastases secondary to tumors. Supragingival irrigation applied as monotherapy and in combination with root planning or BFs related bone necrosectomy revealed that supragingival irrigation with a variety of agents reduced the gingival microbial load and gingival inflammation. In this 4-year follow-up study we analyze the use of hydrogen peroxide (H2O2) as an antimicrobial agent for maintenance periodontal health, improving the longevity of teeth and oral cavity healing process.


Subject(s)
Alveolar Bone Loss/drug therapy , Bisphosphonate-Associated Osteonecrosis of the Jaw/complications , Hydrogen Peroxide/administration & dosage , Hydrogen Peroxide/pharmacology , Mandibular Nerve , Periodontal Diseases/complications , Periodontal Diseases/drug therapy , Bone Density Conservation Agents/adverse effects , Diphosphonates/adverse effects , Follow-Up Studies , Humans , Osteonecrosis/drug therapy
7.
J Biol Regul Homeost Agents ; 33(1 Suppl. 1): 67-77, 2019.
Article in English | MEDLINE | ID: mdl-30966734

ABSTRACT

The atrophic posterior ridges are usually characterized by poor bone quality and quantity: this situation requires the use of bone regenerative techniques. Other alternative surgical approaches are investigated. Nowadays the use of tilted implants offers some advantages due to its feasibility. Today, bone grafting may be practical, but depends on many factors, such as the type of bone graft used (autogenous, alloplastic, or xenograft), host response, age of the patient, various complications associated with grafting procedures, infection, and, most importantly, the time spent while the grafted material matures and is taken up by the bone. So this case report describes the feasibility of an alternative surgical technique.


Subject(s)
Alveolar Bone Loss , Dental Implants , Immediate Dental Implant Loading , Alveolar Bone Loss/surgery , Bone Regeneration , Bone Transplantation , Follow-Up Studies , Humans , Maxilla/diagnostic imaging , Maxilla/surgery , Prostheses and Implants , Treatment Outcome
8.
Transplant Proc ; 49(4): 736-739, 2017 May.
Article in English | MEDLINE | ID: mdl-28457384

ABSTRACT

INTRODUCTION: Hepatic artery thrombosis (HAT) is a well-recognized complication of liver transplantation (LT). HAT is an important risk factor for infectious, in particular hepatic abscess, which can cause graft loss and increasing morbidity and mortality. CASE REPORT: We present a case report of complicated LT in a 52-year-old Caucasian man with primary sclerosing cholangitis. In 2007 the patient was included on the waiting list in Padua for LT. In 2012 the patient underwent percutaneous transhepatic biliary drainage for bile duct stricture, complicated with acute pancreatitis. A diagnostic laparoscopy was performed with choledochotomy and Kehr's T tube drainage. On February 14, 2012, the patient underwent LT with arterial reconstruction and choledochojejunostomy. The postoperative course was complicated with HAT, multiple liver abscesses, and sepsis associated with bacteremia due to Enterococcus faecium despite massive intravenous antibiotic therapy and percutaneous drainages. On November 28, 2012, the patient underwent retransplantation. Four years after transplantation the patient is still in good general condition. CONCLUSION: Hepatic abscess formation secondary to HAT following LT is a major complication associated with important morbidity and mortality. In selected cases retransplantation should be considered as our case demonstrates.


Subject(s)
Hepatic Artery/pathology , Liver Transplantation/adverse effects , Reoperation , Thrombosis/etiology , Humans , Liver Abscess/etiology , Male , Middle Aged , Reoperation/adverse effects , Risk Factors , Time Factors
9.
Eur J Orthod ; 21(3): 223-30, 1999 Jun.
Article in English | MEDLINE | ID: mdl-10407532

ABSTRACT

The purpose of this experimental study was to evaluate the effect of early orthodontic loading on the stability and bone-implant interface of titanium implants in a rabbit model. Twenty-four short threaded titanium fixtures were inserted in the calvarial mid-sagittal suture of 10 rabbits. Two weeks following insertion, 20 implants (test group) were subjected to continuous distalization forces of 150 g for a period of 8 weeks. The remaining four implants (control group) were left unloaded for the same follow-up interval. Clinically, all implants except for one test fixture were stable, and exhibited no mobility or displacement throughout the experimental loading period. Histologically, all stable implants were well-integrated into bone. No differences could be found between the pressure and tension surfaces of the test implants relative to bone quality and density within a range of 1000 microns from the fixture surface. Similarly, qualitative differences were not observed between the apical and coronal portions of test fixtures. Morphometrically, a mean percentage bone-to-implant contact of 76.00 +/- 18.73 per cent was found at the test pressure sides, 75.00 +/- 11.54 per cent at the test tension sides, and 68.00 +/- 15.55 per cent at the control unloaded surfaces. No statistically significant differences in the percentage of bone-to-metal contact length fraction were found between test pressure surfaces, test tension surfaces, and unloaded control surfaces. Marginal bone resorption around the implant collar or immediately beneath it was found in roughly the same percentage of analysed sites in the test and control fixtures. In contrast, slight bone apposition was demonstrated at the implant collar of the test pressure surfaces, while no apposition or resorption were observed in the test tension zones. This study suggests that short endosseous implants can be used as anchoring units for orthodontic tooth movement early in the post-insertion healing period.


Subject(s)
Dental Stress Analysis , Implants, Experimental , Orthodontic Appliance Design , Analysis of Variance , Animals , Bone Density , Bone Resorption , Compressive Strength , Dental Implantation, Endosseous , Dental Implants , Rabbits , Skull/surgery , Tensile Strength , Weight-Bearing
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