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Hum Immunol ; 76(6): 395-6, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25797202

ABSTRACT

One thousand individuals from Belfast, Northern Ireland were genotyped at the HLA-A, -B, -C and -DRB1 loci using sequence-specific oligonucleotide probe methods. HLA-A locus genotypes display a minor Hardy-Weinberg (HW) deviation (p=0.0375); HLA-B, -C and -DRB1 genotypes are consistent with expected HW proportions. These genotype data are available in the Allele Frequencies Net Database under identifier AFND 1243.


Subject(s)
HLA-A Antigens/genetics , HLA-B Antigens/genetics , HLA-C Antigens/genetics , HLA-DRB1 Chains/genetics , Alleles , Gene Frequency , Genetic Loci , Genetics, Population , Genome, Human , Genotyping Techniques , HLA-A Antigens/classification , HLA-A Antigens/immunology , HLA-B Antigens/classification , HLA-B Antigens/immunology , HLA-C Antigens/classification , HLA-C Antigens/immunology , HLA-DRB1 Chains/classification , HLA-DRB1 Chains/immunology , Humans , Northern Ireland
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