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Chirurgia (Bucur) ; 99(4): 247-53, 2004.
Article in Romanian | MEDLINE | ID: mdl-15560562

ABSTRACT

This article presents a case of acute intermittent porphyria admitted to the Surgery Department of C.F. Craiova Hospital between 18.08.2003-26.08.2003 then transferred to the Colentina Hospital in Bucharest for diagnosis confirmation and adequate treatment. The purpose of this paper is to bring attention on a rare metabolic inherited disease that, due to its non-specific and often noisy symptoms and limited possibilities of biochemical, enzymatic and genetic diagnosis, could generate potential serious confusions. The presentes case illustrates the fact that sometimes the acute attack may be mistaken for an acute surgical affection which requires an emergency operation with all the aggravating consequences and delay in the real diagnosis. About 1% of acute attacks of porphyria may be fatal. Only the drugs known as safe should be prescribed. Basic treatment consists in oral and intravenous glucose and hematin administration.


Subject(s)
Abdomen, Acute/diagnosis , Porphyria, Acute Intermittent/diagnosis , Abdomen, Acute/drug therapy , Diagnosis, Differential , Drug Therapy, Combination , Glucose/therapeutic use , Hemin/therapeutic use , Humans , Male , Middle Aged , Porphyria, Acute Intermittent/drug therapy , Treatment Outcome
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