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J Infect Dev Ctries ; 5(8): 587-91, 2011 Aug 12.
Article in English | MEDLINE | ID: mdl-21841302

ABSTRACT

INTRODUCTION: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection is an increasing problem worldwide. In developing countries, there is little data on CA-MRSA infection in children. This study reviewed the clinical features and outcomes of children admitted in a Tunisian pediatric intensive care unit with severe CA-MRSA infections. METHODOLOGY: Retrospective chart review of patients coded for CA-MRSA over 10 years. RESULTS: There were 14 (0.32% of all admissions) patients identified with severe CA-MRSA infections. The median age was three months (range, 0.5-156 months). All patients had pulmonary involvement. Six children (42.8%) developed septic shock. Two (14.3%) patients had multifocal infection with deep venous thrombosis. Two (14.3%) patients died. CONCLUSIONS: Severe CA-MRSA pneumonia dominated presentation. The mortality of CA-MRSA infection in our series is lower than that previously reported.


Subject(s)
Community-Acquired Infections/mortality , Community-Acquired Infections/physiopathology , Intensive Care Units, Pediatric/statistics & numerical data , Methicillin-Resistant Staphylococcus aureus/pathogenicity , Staphylococcal Infections/mortality , Staphylococcal Infections/physiopathology , Adolescent , Child , Child, Preschool , Community-Acquired Infections/microbiology , Developing Countries , Female , Humans , Infant , Lung Diseases/microbiology , Lung Diseases/mortality , Lung Diseases/physiopathology , Male , Severity of Illness Index , Staphylococcal Infections/microbiology , Tunisia/epidemiology
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