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1.
BMC Med Ethics ; 23(1): 86, 2022 08 24.
Article in English | MEDLINE | ID: mdl-36002822

ABSTRACT

BACKGROUND: Implicit prejudice can lead to disparities in treatment. The effects of specialty and experience on implicit obesity and mental illness prejudice had not been explored. The main objective was to examine how specializing in psychiatry/general medicine and years of experience moderated implicit obesity and mental illness prejudice among Swiss physicians. Secondary outcomes included examining the malleability of implicit bias via two video interventions and a condition of cognitive load, correlations of implicit bias with responses to a clinical vignette, and correlations with explicit prejudice. METHODS: In stage 1, participants completed an online questionnaire including a clinical vignette. In stage 2, implicit prejudice pre- and post- intervention was tested using a 4 × 4 between-subject design including a control group. In stage 3, explicit prejudice was tested with feeling thermometers and participants were debriefed. Participants were 133 psychiatrists and internists working in Geneva, hospital-based and private practice. Implicit prejudice was assessed using a Weight IAT (Implicit Association Test) and a Mental Illness IAT. Explicit feelings towards the obese and the mentally ill were measured using Feeling Thermometers. A clinical vignette assessed the level of concern felt for a fictional patient under four conditions: control, obese, depression, obese and depression. Linear regression was conducted to test for association of gender, experience, and specialty with responses to vignettes, pre-intervention IATs and explicit attitudes, and to test for association of interventions (or control) with post-intervention IATs and explicit attitudes. Reported effect sizes were computed using Cohen's d. Two-tailed p < 0.05 was selected as the significance threshold. RESULTS: Compared to internists, psychiatrists showed significantly less implicit bias against mentally vs. physically ill people than internists and warmer explicit feelings towards the mentally ill. More experienced physicians displayed warmer explicit feelings towards the mentally ill and a greater level of concern for the fictional patients in the vignette than the less experienced, except when the patient was described as obese. CONCLUSIONS: Specialty moderates both implicit and explicit mental illness prejudice. Experience moderates explicit mental illness bias and concern for patients. The effect of specialty on implicit prejudice seems to be based principally on self-selection.


Subject(s)
Mentally Ill Persons , Physicians , Psychiatry , Attitude of Health Personnel , Humans , Obesity , Physicians/psychology , Prejudice
2.
Toxins (Basel) ; 13(11)2021 11 22.
Article in English | MEDLINE | ID: mdl-34822614

ABSTRACT

Body tissue and venom glands from an eastern population of the scorpion Centruroides vittatus (Say, 1821) were homogenized and molecular constituents removed to characterize putative sodium ß toxin gene diversity, RT-qPCR, transcriptomic, and proteomic variation. We cloned sodium ß toxins from genomic DNA, conducted RT-qPCR experiments with seven sodium ß toxin variants, performed venom gland tissue RNA-seq, and isolated venom proteins for mass spectrophotometry. We identified >70 putative novel sodium ß toxin genes, 111 toxin gene transcripts, 24 different toxin proteins, and quantified sodium ß toxin gene expression variation among individuals and between sexes. Our analyses contribute to the growing evidence that venom toxicity among scorpion taxa and their populations may be associated with toxin gene diversity, specific toxin transcripts variation, and subsequent protein production. Here, slight transcript variation among toxin gene variants may contribute to the major toxin protein variation in individual scorpion venom composition.


Subject(s)
Proteins/chemistry , Scorpion Venoms/toxicity , Scorpions , Animals , DNA/genetics , Female , Gene Expression Regulation , Genomics , Male , Proteomics , Scorpion Venoms/chemistry , Scorpion Venoms/genetics , Transcriptome
3.
BMC Psychol ; 7(1): 29, 2019 May 16.
Article in English | MEDLINE | ID: mdl-31097028

ABSTRACT

BACKGROUND: Implicit biases are present in the general population and among professionals in various domains, where they can lead to discrimination. Many interventions are used to reduce implicit bias. However, uncertainties remain as to their effectiveness. METHODS: We conducted a systematic review by searching ERIC, PUBMED and PSYCHINFO for peer-reviewed studies conducted on adults between May 2005 and April 2015, testing interventions designed to reduce implicit bias, with results measured using the Implicit Association Test (IAT) or sufficiently similar methods. RESULTS: 30 articles were identified as eligible. Some techniques, such as engaging with others' perspective, appear unfruitful, at least in short term implicit bias reduction, while other techniques, such as exposure to counterstereotypical exemplars, are more promising. Robust data is lacking for many of these interventions. CONCLUSIONS: Caution is thus advised when it comes to programs aiming at reducing biases. This does not weaken the case for implementing widespread structural and institutional changes that are multiply justified.


Subject(s)
Prejudice/prevention & control , Stereotyping , Humans
4.
BMC Med Ethics ; 18(1): 19, 2017 03 01.
Article in English | MEDLINE | ID: mdl-28249596

ABSTRACT

BACKGROUND: Implicit biases involve associations outside conscious awareness that lead to a negative evaluation of a person on the basis of irrelevant characteristics such as race or gender. This review examines the evidence that healthcare professionals display implicit biases towards patients. METHODS: PubMed, PsychINFO, PsychARTICLE and CINAHL were searched for peer-reviewed articles published between 1st March 2003 and 31st March 2013. Two reviewers assessed the eligibility of the identified papers based on precise content and quality criteria. The references of eligible papers were examined to identify further eligible studies. RESULTS: Forty two articles were identified as eligible. Seventeen used an implicit measure (Implicit Association Test in fifteen and subliminal priming in two), to test the biases of healthcare professionals. Twenty five articles employed a between-subjects design, using vignettes to examine the influence of patient characteristics on healthcare professionals' attitudes, diagnoses, and treatment decisions. The second method was included although it does not isolate implicit attitudes because it is recognised by psychologists who specialise in implicit cognition as a way of detecting the possible presence of implicit bias. Twenty seven studies examined racial/ethnic biases; ten other biases were investigated, including gender, age and weight. Thirty five articles found evidence of implicit bias in healthcare professionals; all the studies that investigated correlations found a significant positive relationship between level of implicit bias and lower quality of care. DISCUSSION: The evidence indicates that healthcare professionals exhibit the same levels of implicit bias as the wider population. The interactions between multiple patient characteristics and between healthcare professional and patient characteristics reveal the complexity of the phenomenon of implicit bias and its influence on clinician-patient interaction. The most convincing studies from our review are those that combine the IAT and a method measuring the quality of treatment in the actual world. Correlational evidence indicates that biases are likely to influence diagnosis and treatment decisions and levels of care in some circumstances and need to be further investigated. Our review also indicates that there may sometimes be a gap between the norm of impartiality and the extent to which it is embraced by healthcare professionals for some of the tested characteristics. CONCLUSIONS: Our findings highlight the need for the healthcare profession to address the role of implicit biases in disparities in healthcare. More research in actual care settings and a greater homogeneity in methods employed to test implicit biases in healthcare is needed.


Subject(s)
Attitude of Health Personnel , Health Personnel , Healthcare Disparities , Prejudice , Professional-Patient Relations , Unconscious, Psychology , Humans
5.
Bioethics ; 28(1): 24-32, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24117613

ABSTRACT

The conception of conscience that dominates discussions in bioethics focuses narrowly on private regulation of behaviour resulting from explicit attitudes. It neglects to mention implicit attitudes and the role of social feedback in becoming aware of one's implicit attitudes. But if conscience is a way of ensuring that a person's behaviour is in line with her moral values, it must be responsive to all aspects of the mind that influence behaviour. There is a wealth of recent psychological work demonstrating the influence of implicit attitudes on behaviour. A necessary part of having a well-functioning conscience must thus be awareness and regulation of one's implicit attitudes in addition to one's explicit attitudes; this cannot be done by an individual in isolation. On my revised conception of conscience, heeding social feedback, being emotionally self-aware and engaging in self-monitoring are important for the possession of a well-functioning conscience. Health professionals may need specific training to help them develop and maintain a well-functioning conscience, which should involve cultivation of awareness of implicit attitudes, emphasis on social feedback and techniques to enable better control over them.


Subject(s)
Attitude of Health Personnel , Awareness , Conscience , Ethics, Clinical , Health Personnel , Social Control, Informal , Health Personnel/ethics , Health Personnel/psychology , Humans , Surveys and Questionnaires
6.
Organon F (Bratisl) ; 16(1): 105-123, 2009 Feb.
Article in English | MEDLINE | ID: mdl-22661905

ABSTRACT

This paper aims to move the debate over the status of the conflict between emotion and judgement forward by refuting three implicit claims: that conflict between emotion and judgement is always to be avoided; that any conflict should always be resolved and, moreover, that it should be resolved immediately; that judgement should usually take priority in any resolution. Refutation of these three claims leads to recognition of the wide variety of different cases of conflict between emotion and judgement; examination of these cases is aided by consideration of the social context in which the conflicts occur.

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