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1.
J Matern Fetal Neonatal Med ; 25(10): 1884-8, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22385390

ABSTRACT

OBJECTIVE: To determine whether cervical dilation at the time of physical examination indicated cerclage placement can predicts latency and gestational age at delivery. METHODS: A retrospective cohort study of all women who underwent physical examination indicated cerclage placement from 1996 to 2011 at Duke University Hospital (DUH) was performed. Physical examination indicated cerclage was defined as cerclage placement after 16 weeks in women with a cervical length of less than 2.5 cm and/or cervical dilation greater than or equal to 1 cm at time of procedure. Subjects were divided into two groups depending on cervical dilation at time of procedure (2 cm, <2 cm) for comparison. A multivariate linear regression model for the outcome gestational age of delivery was constructed, controlling for confounding variables. RESULTS: A total of 110 women with complete data were available for analysis. Median gestational age at cerclage placement was similar between the two groups (20.3 vs. 20.3 weeks, p = 0.8). Women with cervical dilatation ≥ 2 cm dilation delivered at an earlier median gestational age than women with cervical dilation <2 cm (27.0 vs. 35.6 weeks, p < 0.001). Cervical dilation at the time of cerclage placement independently predicted gestational age at delivery while controlling for use of intracervical Foley balloon catheter for membrane reduction, cerclage suture type, history of prior preterm birth, race, insurance status, and tobacco use. CONCLUSIONS: Women who receive a rescue cerclage are more likely to deliver at an earlier gestational age when cervical dilation is ≥ 2 cm at the time of procedure.


Subject(s)
Cerclage, Cervical , Cervix Uteri/pathology , Premature Birth/prevention & control , Uterine Cervical Incompetence/surgery , Adult , Cervix Uteri/surgery , Cohort Studies , Emergencies , Female , Gestational Age , Gynecological Examination , Humans , Linear Models , Multivariate Analysis , Pregnancy , Pregnancy Outcome , Premature Birth/etiology , Prenatal Care , Retrospective Studies , Treatment Outcome , Uterine Cervical Incompetence/diagnosis
2.
BJOG ; 118(6): 735-40, 2011 May.
Article in English | MEDLINE | ID: mdl-21392243

ABSTRACT

OBJECTIVE: To evaluate the risk of funisitis among women with preterm prelabour rupture of the membranes (PPROM) and subsequent bleeding per vaginam. DESIGN: Prospective cohort study. SETTING: A University Hospital in the USA. POPULATION: A total of 157 women with PPROM, divided into those with bleeding per vaginam during the hospital admission (n = 46) and those without bleeding per vaginam (n = 111). METHODS: Pathologist blinded to bleeding status assessed placental pathology for funisitis. MAIN OUTCOME MEASURES: Funisitis. RESULTS: Women with bleeding per vaginam were more likely to have funisitis (67.4% versus 36%, P < 0.001) compared with those without bleeding. Logistic regression demonstrated that bleeding per vaginam predicted funisitis after controlling for gestational age at admission, latency period and gestational age at delivery. CONCLUSIONS: Among women with PPROM, those with bleeding per vaginam are more likely to have funisitis than those without bleeding per vaginam.


Subject(s)
Chorioamnionitis/etiology , Fetal Membranes, Premature Rupture , Uterine Hemorrhage/etiology , Adult , Female , Gestational Age , Humans , Pregnancy , Pregnancy Outcome , Prospective Studies , Risk Factors
3.
J Bone Joint Surg Br ; 60-B(4): 504-9, 1978 Nov.
Article in English | MEDLINE | ID: mdl-711797

ABSTRACT

One hundred and two fractures of the femoral shaft, including eighteen pathological fractures, in 100 patients were internally fixed by closed Küntscher nailing. Sixty-eight fractures resulted from motor vehicle accidents; ten were compound. Seventy-five patients were under the age of thirty years and thirty-four had multiple injuries. Sixty-nine fractures were nailed on the day of the accident and the operative technique is described. Complications during and after operations were few. Fifty-eight patients left hospital within four weeks and 77% of those working returned to work in less than four months. There were no wound or bone infections. The results are discussed and it is concluded that, with the correct equipment and careful attention to detail, closed nailing is a straightforward procedure with few complications. Advantages include the wide range of fractures that can be nailed, the short hospitalisation, the rapid return of function to the knee, the early return to work and the absence of infection.


Subject(s)
Femoral Fractures/surgery , Fracture Fixation, Intramedullary/methods , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Postoperative Care , Postoperative Complications
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