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Arch Clin Neuropsychol ; 32(2): 215-227, 2017 Mar 01.
Article in English | MEDLINE | ID: mdl-28365746

ABSTRACT

OBJECTIVE: This study examines the validity of the NAB Screening Module (screening module of the neuropsychological assessment battery, S-NAB) in an acute traumatic brain injury (TBI) inpatient population and provides psychometric evaluation of an original index sensitive to TBI impairment. METHOD: The utility of the S-NAB as a TBI screen was examined using a between groups design. One-hundred and four patients with mild complicated to severe TBI were recruited from a consecutive cohort of patients admitted as inpatients to a UK Major Trauma Centre. Ninety-eight control participants were selected from the S-NAB normative sample. All TBI patients completed the S-NAB during their inpatient stay. RESULTS: Control participants scored significantly higher than TBI participants on the Total Screening index (t = 3.626, p < 0.01), The Attention index (t = 7.882, p < 0.01), and the Executive index (t = 5.577, p < 0.01). A briefer TBI Impairment index of six subtests was constructed which accurately discriminated TBI patients from normative controls (t = 9.9, p < 0.01; Cohen's d = 1.54). The TBI index had excellent classification accuracy (AUC = 0.83), superior to that of the standard S-NAB indices. The TBI Index, Attention Index, and Total Screening Index demonstrated increasing impairment with increased severity of injury. CONCLUSIONS: The S-NAB TBI index is a robust, reliable screening index for use with acute TBI patients, which is sensitive to the effects of acute TBI. It affords a briefer cognitive screen than the S-NAB and demonstrates a dose response relationship to TBI severity.


Subject(s)
Brain Injuries, Traumatic/complications , Brain Injuries, Traumatic/psychology , Cognition Disorders/diagnosis , Cognition Disorders/etiology , Neuropsychological Tests , Adult , Attention Deficit Disorder with Hyperactivity/diagnosis , Attention Deficit Disorder with Hyperactivity/etiology , Cohort Studies , Executive Function/physiology , Female , Glasgow Outcome Scale , Humans , Logistic Models , Male , Mass Screening , Memory/physiology , Middle Aged , ROC Curve , Severity of Illness Index
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