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[Accumulation of the infectious virus and the viral antigen during the multiplication of the hepatitis A virus in an embryonic kidney cell culture of the rhesus macaque (FRhK-4)]. / Nakoplenie infektsionnogo virusa i virusnogo antigena pri razmnozhenii virusa gepatita A v kul'ture kletok pochki émbriona makaki rezusa (FRhK-4).

Kusov, Iu Iu; Fleer, G P; Zavodova, T I; Panina, L I; Donets, M A.

Vopr Virusol ; 32(3): 307-12, 1987.

Article in Russian | MEDLINE | ID: mdl-2445108

ABSTRACT

Growth characteristics of the HAS-15 strain of human hepatitis A virus (HAV) in rhesus monkey foetal kidney cell line (FRhK-4) are described. The conditions optimal for the accumulation of infectious HAV and viral antigen (HAAg) in the infected cells and tissue culture fluids were studied. The production of infectious HAV occurred in the first stage while in the second stage predominantly HAAg was accumulating intracellularly. Serological properties of the cultivated HAV proved to be very similar to those of the HAV occurring in hepatitis A patients.

Subject(s)

Antigens, Viral/analysis , Hepatovirus/physiology , Virus Replication , Animals , Cell Line , Epitopes/analysis , Hepatovirus/immunology , Hepatovirus/isolation & purification , Time Factors , Virus Cultivation/methods

[Comparative study of RNA-dependent DNA polymerases (revertases) of avian myeloblastosis virus and visna virus]. / Sravnitel'noe izuchenie RNK-zavisimykh DNK-polimeraz (revertaz) virusa mieloblastoza ptits i virusa visny

Kavsan, V M; Chumakov, M P; Fleer, G P; Ryndich, A V; Lukshina, O L.

Dokl Akad Nauk SSSR ; 230(1): 227-9, 1976.

Article in Russian | MEDLINE | ID: mdl-61846

Subject(s)

Avian Leukosis Virus/enzymology , Avian Myeloblastosis Virus/enzymology , RNA Viruses/enzymology , RNA-Directed DNA Polymerase/metabolism , Visna-maedi virus/enzymology , Polydeoxyribonucleotides , Polyribonucleotides , Templates, Genetic

[On the plaque-forming ability of various species of mycoplasma]. / O bliashkoobrazuiushchei sposobnosti nekotorykh vidov mikoplazm.

Kagan, G Ia; Fleer, G P; Rakovskaia, I V; Smirnova, T D; Chumakov, M P.

Zh Mikrobiol Epidemiol Immunobiol ; 46(3): 63-6, 1969 Mar.

Article in Russian | MEDLINE | ID: mdl-5784554

Subject(s)

Mycoplasma Infections/immunology , Animals , Chick Embryo , Culture Techniques , Kidney , Rodentia

[The effect of certain Mycoplasma on the formation of plaques by Langat virus in a primary culture of chick embryo cells]. / Vliianie nekotorykh vidov mikoplazm na obrazovanie bliashek virusom lagat v pervichnoi kul'ture kletok kurinogo émbriona.

Fleer, G P; Kagan, G Ia; Rakovskaia, I V; Smirnova, T D.

Vestn Akad Med Nauk SSSR ; 24(5): 68-72, 1969.

Article in Russian | MEDLINE | ID: mdl-5377945

Subject(s)

Encephalitis Viruses, Tick-Borne/growth & development , Mycoplasma/metabolism , Animals , Chick Embryo

Some results of the work on mass immunization in the Soviet Union with live poliovirus vaccine prepared from Sabin strains*

Chumakov, M. P.; Voroshilova, M. K.; Drozdov, S. G.; Dzagurov, S. G.; Lashkevich, V. A.; Mironova, L. L.; Ralph, N. M.; Gagarina, A. V.; Ashmarina, E. E.; Shirman, G. A.; Fleer, G. P.; Tolskaya, E. A.; Sokolova, I. S.; Elbert, L. B.; Sinyak, K. M..

Bull. W.H.O. (Print) ; 25(1): 79-91, 1961.

Article in English | WHO IRIS | ID: who-267398

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