Data Linkages for Wildfire Exposures and Human Health Studies: A Scoping Review.

Wildfires are increasing in frequency and intensity, with significant consequences that impact human health. A scoping review was conducted to: (a) understand wildfire-related health effects, (b) identify and describe environmental exposure and health outcome data sources used to research the impacts of wildfire exposures on health, and (c) identify gaps and opportunities to leverage exposure and health data to advance research. A literature search was conducted in PubMed and a sample of 83 articles met inclusion criteria. A majority of studies focused on respiratory and cardiovascular outcomes. Hospital administrative data was the most common health data source, followed by government data sources and health surveys. Wildfire smoke, specifically fine particulate matter (PM2.5), was the most common exposure measure and was predominantly estimated from monitoring networks and satellite data. Health data were not available in real-time, and they lacked spatial and temporal coverage to study health outcomes with longer latency periods. Exposure data were often available in real-time and provided better temporal and spatial coverage but did not capture the complex mixture of hazardous wildfire smoke pollutants nor exposures associated with non-air pathways such as soil, household dust, food, and water. This scoping review of the specific health and exposure data sources used to underpin these studies provides a framework for the research community to understand: (a) the use and value of various environmental and health data sources, and (b) the opportunities for improving data collection, integration, and accessibility to help inform our understanding of wildfires and other environmental exposures.

Achromatic GRIN singlet lens design.

Gradient refractive index (GRIN) materials are attractive candidates for improved optical design, especially in compact systems. For GRIN lenses cut from spherically symmetric GRIN material, we derive an analogue of the "lens maker's" equation. Using this equation, we predict and demonstrate via ray tracing that an achromatic singlet lens can be designed, where the chromatic properties of the GRIN counterbalance those of the lens shape. Modeling the lens with realistic materials and realistic fabrication geometries, we predict we can make an achromatic singlet with a 19 mm focal length using a matrix of known polymers.

A genomic analysis of transcytosis in the pea aphid, Acyrthosiphon pisum, a mechanism involved in virus transmission.

Aphids are the primary vectors of plant viruses. Transmission can occur via attachment to the cuticle lining of the insect (non-circulative transmission) or after internalization in the insect cells with or without replication (circulative transmission). In this paper, we have focused on the circulative and non-propagative mode during which virions enter the cell following receptor-mediated endocytosis, are transported across the cell in vesicles and released by exocytosis without replicating. The correct uptake, transport and delivery of the vesicles cargo relies on the participation of proteins from different families which have been identified in the Acyrthosiphon pisum genome. Assemblage of this annotated dataset provides a useful basis to improve our understanding of the molecules and mechanisms involved in virus transmission by A. pisum and other aphid species.

Optical properties of a bio-inspired gradient refractive index polymer lens.

The design, fabrication, and properties of one of a new class of gradient-index lenses are reported. The lens is an f/2.25 GRIN singlet based on a nanolayered polymer composite material, designed to correct for spherical aberration. The light gathering and focusing properties of the polymer lens are compared to a homogeneous BK7 glass singlet with a similar f-number. The modulation transfer function of the polymer GRIN lens exceeded that of the homogeneous glass lens at all spatial frequencies and was as much as 3 times better at 5 cyc/mm. The weight of the polymer lens was approximately an order of magnitude less than the homogeneous glass lens.

TOMBO sensor with scene-independent superresolution processing.

One approach to flat sensor design is to use a lenslet array to form multiple subimages of a scene and then combine the subimages to recover a fully sampled image by using a superresolution algorithm. Previously, superresolution image assembly has been based on information derived from the observed scene. For lenslet arrays, we propose a new scene-independent approach based only on known imager properties in which relative subimage shifts are accurately estimated with a calibration procedure using point source imaging. Thus, the relative resolution enhancement provided by the scene-independent superresolution algorithm is impervious to changes in subimage content, contrast, sharpness, and noise.

Analysis and application of multiframe superresolution processing for conventional imaging systems and lenslet arrays.

Low-cost compact sensors for ultrasmall systems are a pressing need in many new applications. One potential solution is a shallow aspect ratio system using a lenslet array to form multiple undersampled subimages of a scene on a single focal plane array, where processing techniques then produce an upsampled restored image. We have investigated the optimization and theoretical limits of the performance of such arrays. We have built a hardware simulator and developed algorithms to process imagery similar to that of a full lenslet imaging sensor, which allowed us to quickly test optical components, algorithms, and complete system designs for future lenslet imaging systems.