Subject(s)
Azathioprine/therapeutic use , Eosinophilia/drug therapy , Fasciitis/drug therapy , Immunosuppressive Agents/therapeutic use , Scleroderma, Localized/drug therapy , Aged , Eosinophilia/complications , Eosinophilia/pathology , Fasciitis/complications , Fasciitis/pathology , Humans , Male , Scleroderma, Localized/complications , Scleroderma, Localized/pathologyABSTRACT
Cutaneous plasmacytomas are monoclonal proliferations of plasma cells which can be classified into primary (with no other concomitant bony or extramedullary disease) or secondary (generally associated with multiple myeloma (MM), extramedullary plasmacytoma, or plasma cell leukemia). Cutaneous plasmacytomas can appear in some patients with MM and, rarely, the skin lesions suppose the first clinical manifestation of the disease. Their development is considered as a poor prognostic sign, associated with a life expectancy of less than 12 months after diagnosis. An unusual case of MM is described, in which the histopathological study of a skin nodule provided invaluable information for diagnosis.
Subject(s)
Multiple Myeloma/pathology , Skin Neoplasms/pathology , Skin/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Biomarkers, Tumor/analysis , Biopsy , Fatal Outcome , Female , Humans , Immunohistochemistry , Middle Aged , Multiple Myeloma/chemistry , Multiple Myeloma/drug therapy , Predictive Value of Tests , Skin/chemistry , Skin Neoplasms/chemistry , Skin Neoplasms/drug therapySubject(s)
Histiocytosis, Langerhans-Cell/diagnosis , Adrenal Cortex Hormones/therapeutic use , Aged, 80 and over , Dermatologic Agents/therapeutic use , Drug Therapy, Combination , Female , Histiocytosis, Langerhans-Cell/drug therapy , Histiocytosis, Langerhans-Cell/pathology , Humans , Tacrolimus/therapeutic use , Treatment OutcomeSubject(s)
Humans , Male , Aged , Rickettsia/isolation & purification , Rickettsia Infections/diagnosis , Exanthema/microbiology , BiopsySubject(s)
Antimetabolites, Antineoplastic/adverse effects , Deoxycytidine/analogs & derivatives , Erythema/chemically induced , Fluorouracil/analogs & derivatives , Genital Diseases, Male/chemically induced , Paresthesia/chemically induced , Aged , Aged, 80 and over , Capecitabine , Deoxycytidine/adverse effects , Fluorouracil/adverse effects , Genital Diseases, Male/diagnosis , Humans , Male , Scrotum/pathologySubject(s)
DNA, Bacterial/analysis , Exanthema/etiology , Polymerase Chain Reaction , Rickettsia/isolation & purification , Rickettsiaceae Infections/diagnosis , Skin Diseases, Bacterial/diagnosis , Skin/microbiology , Aged , Biopsy , Fever/etiology , Humans , Insect Bites and Stings/microbiology , Male , Polymerase Chain Reaction/methods , Rickettsia/genetics , Rickettsiaceae Infections/epidemiology , Rickettsiaceae Infections/microbiology , Rickettsiaceae Infections/pathology , Rickettsiaceae Infections/transmission , Skin/pathology , Skin Diseases, Bacterial/microbiology , Skin Diseases, Bacterial/pathology , Skin Diseases, Bacterial/transmission , Spain/epidemiology , Species Specificity , Wound Infection/microbiologySubject(s)
Herpes Zoster/immunology , Immunocompromised Host , Skin Diseases, Viral/immunology , Acyclovir/administration & dosage , Chronic Disease , Female , Herpes Zoster/drug therapy , Herpes Zoster/pathology , Humans , Lung Diseases/surgery , Lung Transplantation , Lymphangioleiomyomatosis/surgery , Middle Aged , Skin Diseases, Viral/drug therapyABSTRACT
No disponible
No disponible
Subject(s)
Humans , Female , Aged , Exanthema/chemically induced , Drug Eruptions/etiology , Ketoprofen/analogs & derivatives , Ketoprofen/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Tromethamine/analogs & derivatives , Tromethamine/adverse effectsABSTRACT
No disponible
No disponible
Subject(s)
Humans , Male , Aged , Lymphohistiocytosis, Hemophagocytic/complications , Lymphoma/complications , Lymphohistiocytosis, Hemophagocytic/diagnosis , Lymphoma/diagnosis , Diagnosis, Differential , AutopsyABSTRACT
Sorafenib is an oral multikinase inhibitor that is useful in the treatment of various solid cancer. We report a patient who developed an acneiform facial eruption during treatment with this medication.
Subject(s)
Acneiform Eruptions/chemically induced , Antineoplastic Agents/adverse effects , Facial Dermatoses/chemically induced , Protein Kinase Inhibitors/adverse effects , Adult , Antineoplastic Agents/therapeutic use , Fatal Outcome , Female , Hemangioendothelioma, Epithelioid/drug therapy , Hemangioendothelioma, Epithelioid/surgery , Humans , Liver Neoplasms/drug therapy , Liver Neoplasms/surgery , Liver Transplantation , Neoplasm Proteins/antagonists & inhibitors , Neoplasm Recurrence, Local/drug therapy , Postoperative Complications/chemically induced , Protein Kinase Inhibitors/therapeutic use , Protein-Tyrosine Kinases/antagonists & inhibitorsSubject(s)
Lymphohistiocytosis, Hemophagocytic , Lymphoma, B-Cell , Vascular Neoplasms , Aged , Female , Humans , Lymphohistiocytosis, Hemophagocytic/complications , Lymphohistiocytosis, Hemophagocytic/diagnosis , Lymphoma, B-Cell/complications , Lymphoma, B-Cell/diagnosis , Vascular Neoplasms/complications , Vascular Neoplasms/diagnosisABSTRACT
No disponible
No disponible