ABSTRACT
The aim of this study was to examine the clinical and pathological characteristics of colorectal cancer in Jamaica, to determine whether there was a change in the anatomic distribution and clinical presentation and to discuss the options for diagnosis and management. A comprehensive retrospective review of patients newly diagnosed with colorectal carcinoma was conducted at The University Hospital of the West Indies by reviewing both patient records and pathological data. These data were compared with previous reports of patients with colorectal cancer seen in Jamaica. One hundred and forty-seven patients were studied There were 85 females and 62 males with a female to male ratio of 1.37:1. The median age was 65.5 years (range 19 to 94 years). The predominant symptoms were abdominal pain in 91 patients, change in bowel habit in 77 patients and rectal bleeding in 74 patients. Sixty patients presented with weight loss and 28 with a rectal mass. The most common tumours were right-sided colonic cancers in 42 patients (28.5%) followed by sigmoid colon in 30 (20.4%) rectum in 34 (23.1%) and left and transverse colon accounting for 16 and 10 cases respectively. Most of the tumours were well or moderately differentiated adenocarcinomas. Only eight patients presented with Dukes' A disease, 50 with Dukes'B, 53 with Dukes'C disease and 34 with advanced disease. The findings showed that sigmoid and rectal tumours accounted for 43.5% of cancers. The colon/rectum ratio in this series was 3.3:1 indicating a significant proximal shift of colorectal cancers in this population in keeping with recent reports. The results of the current study suggest that the sub-site location of colorectal cancers seen is similar to that reported in high incidence countries such as the United States of America and parts of Europe but differs from the African continent which has a high proportion of rectal tumours. This right-sided preponderance also differs from previous studies in Jamaica, which report a higher incidence of rectal lesions The detection of early colorectal carcinoma will require screening at a stage when the disease is asymptomatic in order to improve the chance for cure. The data presented here imply that screening programmes should allow evaluation of the entire colon rather than the distal 25 cm.
Subject(s)
Colorectal Neoplasms/epidemiology , Adult , Age Distribution , Aged , Aged, 80 and over , Catchment Area, Health , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/physiopathology , Female , Hospitals, University/statistics & numerical data , Humans , Incidence , Jamaica/epidemiology , Male , Middle Aged , Neoplasm Staging , Sex DistributionABSTRACT
The aim of this study was to examine the clinical and pathological characteristics of colorectal cancer in Jamaica, to determine whether there was a change in the anatomic distribution and clinical presentation and to discuss the options for diagnosis and management. A comprehensive retrospective review of patients newly diagnosed with colorectal carcinoma was conducted at The University Hospital of the West Indies by reviewing both patient records and pathological data. These data were compared with previous reports of patients with colorectal cancer seen in Jamaica. One hundred and forty-seven patients were studied There were 85 females and 62 males with a female to male ratio of 1.37:1. The median age was 65.5 years (range 19 to 94 years). The predominant symptoms were abdominal pain in 91 patients, change in bowel habit in 77 patients and rectal bleeding in 74 patients. Sixty patients presented with weight loss and 28 with a rectal mass. The most common tumours were right-sided colonic cancers in 42 patients (28.5) followed by sigmoid colon in 30 (20.4) rectum in 34 (23.1) and left and transverse colon accounting for 16 and 10 cases respectively. Most of the tumours were well or moderately differentiated adenocarcinomas. Only eight patients presented with Dukes' A disease, 50 with Dukes'B, 53 with Dukes'C disease and 34 with advanced disease. The findings showed that sigmoid and rectal tumours accounted for 43.5 of cancers. The colon/rectum ratio in this series was 3.3:1 indicating a significant proximal shift of colorectal cancers in this population in keeping with recent reports. The results of the current study suggest that the sub-site location of colorectal cancers seen is similar to that reported in high incidence countries such as the United States of America and parts of Europe but differs from the African continent which has a high proportion of rectal tumours. This right-sided preponderance also differs from previous studies in Jamaica, which report a higher incidence of rectal lesions The detection of early colorectal carcinoma will require screening at a stage when the disease is asymptomatic in order to improve the chance for cure. The data presented here imply that screening programmes should allow evaluation of the entire colon rather than the distal 25 cm
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Colorectal Neoplasms/epidemiology , Age Distribution , Sex Distribution , Neoplasm Staging , Hospitals, University , Incidence , Jamaica/epidemiology , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/physiopathology , Catchment Area, HealthABSTRACT
The treatment for thymic tumours and/or myaesthenia gravis (MG) includes thymectomy. Controversy exists as to the optimal timing and operative approach to thymectomy. At the University Hospital of the West Indies, Kingston, Jamaica, the results of thymic surgery during the period 1992 to 2000 were studied retrospectively. There were 26 patients operated on, 17 females and nine males. Twenty-three underwent thymectomy to treat MG, and three to remove a thymoma. The average age for females was 30.7 years, and 25.1 years for males. Average duration of symptoms prior to surgery was 16 months (all patients), and the interval between diagnosis and referral averaged 2.6 months. All patients underwent thymectomy via median sternotomy with a cervical extension of the incision if required. A policy of phrenic nerve preservation, even if residual tumour was left behind, was followed. Patients with thymomas were given post-operative radiotherapy. Chemotherapy was not given to any patient. The medium and long term results of thymic surgery in a developing country are presented. The results are within international norms, although the small patient population makes statistical analysis difficult. There appears to be no need to change current practice, despite the reported efficacy of less invasive approaches to thymic surgery.
Subject(s)
Myasthenia Gravis/surgery , Thymectomy , Thymoma/surgery , Thymus Neoplasms/surgery , Adult , Female , Humans , Jamaica , Male , Treatment OutcomeABSTRACT
The treatment for thymic tumours and/or myaesthenia gravis (MG) includes thymectomy. Controversy exists as to the optimal timing and operative approach to thymectomy. At the University Hospital of the West Indies, Kingston, Jamaica, the results of thymic surgery during the period 1992 to 2000 were studied retrospectively. There were 26 patients operated on, 17 females and nine males. Twenty-three underwent thymectomy to treat MG, and three to remove a thymoma. The average age for females was 30.7 years, and 25.1 years for males. Average duration of symptoms prior to surgery was 16 months (all patients), and the interval between diagnosis and referral averaged 2.6 months. All patients underwent thymectomy via median sternotomy with a cervical extension of the incision if required. A policy of phrenic nerve preservation, even if residual tumour was left behind, was followed. Patients with thymomas were given post-operative radiotherapy. Chemotherapy was not given to any patient. The medium and long term results of thymic surgery in a developing country are presented. The results are within international norms, although the small patient population makes statistical analysis difficult. There appears to be no need to change current practice, despite the reported efficacy of less invasive approaches to thymic surgery
Subject(s)
Humans , Male , Female , Adult , Myasthenia Gravis/surgery , Thymus Neoplasms/surgery , Thymectomy , Thymoma/surgery , Jamaica , Treatment OutcomeABSTRACT
Trauma accounted for 37% of 22,311 patients seen in the Accident and Emergency Unit (A&E Unit) at the University Hospital of the West Indies (UHWI) during 1996. Thirty-nine per cent of injuries were intentional and 18% were due to motor vehicle accidents. Knives, machetes and rocks accounted for 75% of the injuries compared with 5% for gunshot wounds. Passengers were injured in about 40% of motor vehicle accidents and pedestrians in 19%. The admission rate was 16% and the orthopaedic clinic received 75% of the patients referred to specialist clinics. Victims of motor vehicle accidents made up a greater proportion of admissions (24%) than those of intentional violence (13%). The average cost of caring for each patient in the A&E unit was US$70 resulting in an annual cost of US$578,000.
Subject(s)
Wounds and Injuries/economics , Wounds and Injuries/etiology , Adolescent , Adult , Aged , Child , Child, Preschool , Emergency Service, Hospital , Female , Health Care Costs , Humans , Infant , Male , Middle Aged , West Indies/epidemiology , Wounds and Injuries/epidemiologyABSTRACT
This study reports the first 13 cases of biopsy-proven low rectal carcinoma treated by transanal electrocoagulation using a locally manufactured instrument. At the University Hospital of the West Indies, over a 16-year period, 9 patients were treated for cure, six of whom have no clinical evidence of recurrence for one to 12 years. Four cases who were offered this procedure for palliation defaulted after a single treatment. Transanal electrocoagulation provides an additional option for treating patients with small, mobile low rectal cancers, following careful screening for evidence of nodal or distant spread. The procedure can also be used in the local control of disease in patients with distant spread or in whom a major operation is not feasible.
Subject(s)
Adenocarcinoma/surgery , Electrocoagulation , Rectal Neoplasms/surgery , Adult , Aged , Electrocoagulation/instrumentation , Electrocoagulation/methods , Female , Humans , Male , Middle AgedABSTRACT
This study reports the first 13 cases of biopsy-proven low rectal carcinoma treated by transanal electrocoagulation using a locally manufactured instrument. At the University Hospital of the West Indies, over a 16-year period, 9 patients were treated for cure, six of whom have no clinical evidence of recurrence for one to 12 years. Four cases who were offered this procedure for palliation defaulted after a single treatment. Transanal electrocoagulation provides an additional option for treating patients with small, mobile low rectal cancers, following careful screening for evidence of nodal or distant spread. The procedure can also be used in the local control of disease in patients with distant spread or in whom a major operation is not feasible.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Adenocarcinoma/surgery , Electrocoagulation , Rectal Neoplasms/surgery , Electrocoagulation/instrumentation , Electrocoagulation/methodsABSTRACT
Trauma accounted for 37of 22,311 patients seen in the Accident and Emergency Unit (A&E Unit) at the University Hospital of the West Indies (UHWI) during 1996. Thirty-nine per cent of injuries were intentional and 18were due to motor vehicle accidents. Knives, machetes and rocks accounted for 75of the injuries compared with 5for gunshot wounds. Passengers were injured in about 40of motor vehicle accidents and pedestrians in 19. The admission rate was 16and the orthopaedic clinic received 75of the patients referred to specialist clinics. Victims of motor vehicle accidents made up a greater proportion of admissions (24) than those of intentional violence (13). The average cost of caring for each patient in the A&E unit was US$70 resulting in an annual cost of US$578,000.
Subject(s)
Child , Child, Preschool , Humans , Male , Female , Infant , Adolescent , Adult , Middle Aged , Wounds and Injuries/economics , Wounds and Injuries/etiology , Health Care Costs , Wounds and Injuries/epidemiology , Emergency Service, Hospital , West Indies/epidemiologySubject(s)
General Surgery/history , Guyana , History, 20th Century , Humans , Schools, Medical/history , West IndiesSubject(s)
Humans , History, 20th Century , General Surgery/history , Schools, Medical/history , Guyana , West IndiesABSTRACT
A three-fold greater incidence of chemical burn injuries in Jamaican hospitals, compared to burn centres in other industrial countries, underscores the problem of the use of common chemicals for assault weapons in this country. With the increased availability of guns for personal use, many Jamaicans learned the value of carrying household chemicals such as sulphuric acid from batteries or sodium hydroxide obtained from cleaning supplies. Chemicals carried in a container, such as one might carry mace, afforded a means of defence among the lower socioeconomic groups who could not afford handguns. This use of dangerous chemicals for defensive weapons has extended to the use of chemicals for assault. The pattern of chemical injury differs significantly from most reports in the literature in both prevalence and aetiology. This review was prepared to examine these injuries with a view to planning strategies for prevention.
Subject(s)
Burns, Chemical/epidemiology , Violence , Adult , Burns, Chemical/etiology , Burns, Chemical/prevention & control , Female , Humans , Jamaica/epidemiology , Male , Morbidity , Sodium Hydroxide , Sulfuric Acids , Survival RateSubject(s)
Esophagus/injuries , Hemopneumothorax/etiology , Wounds, Nonpenetrating/complications , Adult , Humans , Male , RuptureABSTRACT
One hundred and thirty-eight patients with abdominal aortic aneurysms were treated by aneurysmorrhaphy over an eleven-year period. Six patients, all male and aged 60-74 years, were found to have developed primary aortoenteric fistulae. Four patients presented with bleeding into the gastrointestinal tract in association with a tender abdominal swelling. In the other two cases, the aneurysm was discovered at emergency laparotomy for gastrointestinal haemorrhage. The presence of the fistula was confirmed at operation in five patients and at autopsy in one. Two patients died, one from a massive gastrointestinal haemorrhage prior to surgery, the other from sepsis complicated by Adult Respiratory Distress Syndrome and renal failure following operation.
Subject(s)
Aortic Aneurysm, Abdominal/complications , Aortic Aneurysm, Abdominal/physiopathology , Fistula/complications , Fistula/physiopathology , Iliac Artery/physiopathology , Aged , Aortic Aneurysm, Abdominal/surgery , Fistula/surgery , Gastrointestinal Hemorrhage/etiology , Humans , Iliac Artery/surgery , Laparotomy , Male , Middle Aged , Retrospective StudiesABSTRACT
Two successfully treated cases of benign colovesical fistula are presented. The condition should be suspected whenever patients with colorectal disease develop urinary symptoms. Flexible colonoscopy and a lateral abdominal X-ray should be the initial investigations; but barium enema, cystoscopy and, rarely, CT scan may be necessary to confirm the presence of a colovesical fistula. Patients should be managed conservatively during the acute phase, and then be treated definitively by a single-stage bowel resection. Simple closure or resection and closure is used for the bladder-defect.
Subject(s)
Colonic Diseases/surgery , Intestinal Fistula/surgery , Urinary Bladder Fistula/surgery , Aged , Colonic Diseases/diagnosis , Hospitals, University , Humans , Intestinal Fistula/diagnosis , Jamaica , Male , Middle Aged , Urinary Bladder Fistula/diagnosisABSTRACT
A total colectomy and a mucosal proctectomy with ileo-anal anastomosis (c-mp-iaa) effectively removes all debilitating, potentially malignant colonic mucosa. Preservation of the anorectal sphincter predictably results in good to excellent anal continence with a low mortality and acceptable morbidity. Since 1983 at the University Hospital of the West Indies (U.H.W.I.), Jamaica, five (5) patients have undergone c-mp-iaa for colonic mucosal disease. All have good to excellent anal continence with an average of 2-6 continent, formed stools per day. There were no operative deaths. The five (5) cases are described and a plea is made for the earlier use of this definitive surgical procedure where indicated.
Subject(s)
Anal Canal/surgery , Colonic Diseases/surgery , Ileum/surgery , Proctocolectomy, Restorative , Adolescent , Adult , Anastomosis, Surgical , Child , Female , Humans , Male , Middle Aged , Proctocolectomy, Restorative/methodsABSTRACT
The pathological records of appendicectomy specimens from patients with suspected acute appendicitis at the University Hospital of the West Indies during the 5-year period 1984-1988 were studied. The numbers of cases, their ages, sex and seasonal incidence were similar to those of other studies. The overall false positive diagnosis rate was 25% (16% in males, 38% in females). The main diagnostic difficulty was in young females in whom surgery for suspected appendicitis often proved unnecessary.
Subject(s)
Appendectomy , Appendicitis/diagnosis , Acute Disease , Adolescent , Adult , Aged , Appendicitis/epidemiology , Appendicitis/pathology , Child , Child, Preschool , False Negative Reactions , False Positive Reactions , Female , Hospitals, University , Humans , Incidence , Infant , Male , Middle Aged , Retrospective Studies , Sex Factors , Time Factors , West Indies/epidemiologyABSTRACT
The pathological records of appendicectomy specimens from patients with suspected acute appendicitis at the University Hospital of the West Indies during the 5-year period 1984-1988 were studied. The numbers of cases, their ages, sex and seasonal incidence were similar to those of other studies. The over-all false positive diagnosis rate was 25%(16%in males, 38%in females). The main diagnostic difficulty was in young females in whom surgery for suspected appendicitis often proved unnecessary.
Subject(s)
Humans , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Male , Female , Appendectomy/statistics & numerical data , Appendicitis/diagnosis , Appendicitis/pathology , Sex Factors , Retrospective Studies , Diagnosis, Differential , Diagnostic ErrorsABSTRACT
A case of spontaneous rupture of the colon in a previously asymptomatic patient is herein reported. At laparotomy, apart from the tear in the sigmoid colon, no other pathological problem was present. An awareness of the existence of this condition will lead to early diagnosis and management with improved morbidity and mortality.
Subject(s)
Colonic Diseases/surgery , Colon/surgery , Colostomy , Humans , Male , Middle Aged , Reoperation , Rupture, SpontaneousABSTRACT
A case of spontaneous rupture of the colon in a previously asymptomatic patient is herein reported. At laparotomy, apart from the tear in the sigmoid colon, no other pathological problem was present. An awareness of the existence of this condition will lead to early diagnosis and management with improved morbidity and mortality.