The relationship between scores and outcomes for polytrauma patients in the emergency department. A case study.

AIM: Traumas are one of the most relevant pathological events in health care, because of clinical and prognostic relevance. Morbidity and mortality rates are strongly affected by the timely and correct approach to the patient (golden hour). The objective of this study was to investigate the possible influence of the diagnostic time and of the Injury Severity Score (ISS) on outcomes in trauma patients. MATERIAL OF STUDY: Out of a total of 240,833 emergency patients, we observed, 447 polytrauma. All patients were assessed according to the Advanced Trauma Life Support (ATLS) guidelines, diagnosed by computed tomography (CT), and summarized using an adapted complex trauma card (italian version). RESULTS: Overall, 2.5% (11/447) of patients died during the assessment, whereas the remaining 436 patients were diagnosed at the Emergency room and afterwards hospitalised. In 76 out of 436 patients (17.43%) the outcome was poor. Particularly, the most significant complications involved the central nervous system, chest and abdomen lesions respectively, with an ISS of 41.7 ± 15.9. The mean time for the diagnostic assessment in patients with poor outcome was 115.2 ± 0.4 minutes. DISCUSSION: The immediate mortality percentage, as well as the delayed ones, was highest in patients involved in road accidents. The early management certainly plays a crucial role, reducing death rate and permanent disability. CONCLUSIONS: The high percentage of patients affected by haemodynamic instability (24.3%) demonstrates the existence of a criticality identifiable in the approach to the patient during the pre-hospital phase: a phase that is dramatically characterised by the exclusion of intensivists from rescue teams. KEY WORDS: Complex Trauma Card, Mortality, Multiple injuries, Polytrauma, Scores.

Pattern of nodal involvement in papillary thyroid cancer: a challenge of quantitative analysis.

INTRODUCTION: Backgrounds of this study were to examine and analyse the relationship among the number of lymph nodes with metastases harvested in central and lateral compartments, the characteristics of tumours and patients, and the recurrences rate. METHODS: A retrospective review of 118 patients treated for a papillary thyroid cancer and underwent to neck dissection, including in all cases both central and lateral compartment, was realised. A quantitative analysis, on this homogeneous cohort of patients, was performed to hypothesize the minimum number of cervical lymph nodes to be necessarily excised in order to obtain an adequate management of these patients. RESULTS: The mean follow-up time was 75.9 months. Five-year overall survival was 96.6%. The correlation among the metastatic lymph node number of the ipsilateral central compartment, isolated or pooled with those of the ipsilateral lateral compartment, age of patient and tumour size revealed a statistical significance (P=0.01); both parameters, tumour size and age, may be considered as dependent predictor variables. CONCLUSION: We suppose, notwithstanding the limited number of patients, that the number of lymph nodes harvested to achieve an optimal cervical dissection may be superior to 8 and 11 in central and lateral compartments, and 6 and 10 in contralateral ones, respectively. Moreover we recommend the bilateral dissection of central nodes compartment in presence of tumour localised in the isthmus.

Giant retroperitoneal leiomyoma: a case report and review of the literature.

UNLABELLED: Retroperitoneal leiomyomata are infrequent, and their prevalence among primary retroperitoneal tumours has been estimated as 0.5-1.2%. The authors report a case of symptomatic retroperitoneal leiomyoma with a favourable prognosis. A 53-year-old woman presented for abdominal pain associated to an inflammatory syndrome. A contrast-enhanced computed tomography revealed a large abdominopelvic mass and patient underwent open surgical excision. Definitive diagnosis was done after immunohistochemical assessment. Immunoreactivity was strong for smooth muscular actin. Presence of oestrogen and progesterone receptor proteins was also detected. Prognosis of these well-differentiated smooth muscle tumours is generally favourable but a postoperative surveillance is always recommended. KEY WORDS: Leiomyoma, Retroperitoneal space, Surgery.