ABSTRACT
An abdominal wall Actinomyces abscess occurred in a woman with an intrauterine device. Contributing factors were local trauma, spread from surrounding colonized body sites and symbiotic growth of other anaerobes. The diagnosis was based on the histologic finding of the sulfur granule. Special studies may be needed to distinguish this condition from other, similar ones (Nocardia, botryomycosis).
Subject(s)
Abdominal Muscles , Abscess/etiology , Actinomycosis/etiology , Intrauterine Devices , Abscess/diagnosis , Abscess/therapy , Actinomycosis/diagnosis , Actinomycosis/therapy , Anti-Bacterial Agents/therapeutic use , Clinical Protocols/standards , Decision Trees , Female , Humans , Inhalation , Middle Aged , Pelvis/diagnostic imaging , Tomography, X-Ray Computed , UltrasonographyABSTRACT
The mechanisms of action of danazol are unknown and the alteration of normal human endocrine values during danazol therapy is controversial. Twenty patients were given 200-800 mg of danazol daily. Control and treatment blood serum samples were obtained with serial endometrial biopsies and basal body temperatures. LH-FSH basal levels, prolactin, TSH, TBG, thyroxine, cortisol, and androstenedione were not changed by either dosage or duration of danazol therapy. Estrone and estradiol serum levels were modestly decreased and were not dose-dependent. There were significant dose related increases in serum testosterone and DHEA-S. Endometrial atrophy occurred at all dose levels.
