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Clin Ter ; 159(1): 23-8, 2008.
Article in Italian | MEDLINE | ID: mdl-18399258

ABSTRACT

AIMS: Analysis of the intra-operative anesthesia related problems were compared during intra-lesional or extra-lesional surgeries for patients with metastatic renal cell carcinoma to the spine. MATERIALS AND METHODS: We retrospectively collected and analyzed the hemodynamic data on 30 patients who had undergone surgical intervention. Twenty patients had an intra-lesional excision of the metastatic lesion in the vertebra, whereas for the rest, an en-bloc wide or marginal margin resection was carried out. RESULTS: The surgical time for the en-bloc resections was much longer, and thus also the exposure to the anesthesia, but lesser variability within the data on blood pressure and pulse as compared with intra-lesional curettage. There was also more blood loss with the intra-lesional surgeries. CONCLUSIONS: En-bloc resections of the vertebral tumors not only give better oncological local control, but also have less compromising effects on the patient, especially with respect to the intra-operative hemodynamics. In selected cases, en-bloc resections present a good option of treatment in vertebral metastases, and especially in highly vascular tumors such as the renal cell carcinoma metastases.


Subject(s)
Anesthesia/adverse effects , Carcinoma, Renal Cell/surgery , Kidney Neoplasms/pathology , Lumbar Vertebrae/surgery , Spinal Neoplasms/surgery , Thoracic Vertebrae/surgery , Adult , Aged , Aged, 80 and over , Anesthesia/methods , Carcinoma, Renal Cell/secondary , Debridement/methods , Female , Humans , Intraoperative Period , Male , Middle Aged , Neurosurgical Procedures/methods , Retrospective Studies , Spinal Neoplasms/secondary , Treatment Outcome
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