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14.
Vopr Onkol ; 24(1): 48-50, 1978.
Article in Russian | MEDLINE | ID: mdl-305685

ABSTRACT

Under study was the effect of the albumin fraction of soluble placental proteins on the transformation of T- and B-lymphocytes, stimulated by Salmonellae phytohemagglutinin and lipopolysaccharides, respectively. Placental proteins were separated by their fractional sedimentation with ammonium sulphate and subsequent gelfiltration on Sephadex-G-200. The albumin fraction of placental proteins was shown to stimulated the reaction of the T- and B-lymphocytes blasttransformation. Some possible mechanisms of this effect are discussed.


Subject(s)
Albumins/pharmacology , B-Lymphocytes/drug effects , Lymphocyte Activation/drug effects , Placenta , T-Lymphocytes/drug effects , Albumins/isolation & purification , Cells, Cultured , Female , Humans , Lectins/pharmacology , Lipopolysaccharides/pharmacology , Pregnancy , Salmonella , Solubility , Stimulation, Chemical
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