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Neurology ; 66(12): 1938-40, 2006 Jun 27.
Article in English | MEDLINE | ID: mdl-16801667

ABSTRACT

To assess short- and long-term seizure freedom, the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy. The mean follow-up duration was 5.5 years (range 1 to 14.1 years). Fifty-three percent of patients were seizure free at 10 years. The authors identified multiple predictors of recurrence. Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence, in addition to breakthrough seizures with discontinuation of antiepileptic drugs.


Subject(s)
Anterior Temporal Lobectomy/statistics & numerical data , Epilepsy/diagnosis , Epilepsy/surgery , Outcome Assessment, Health Care/methods , Proportional Hazards Models , Risk Assessment/methods , Severity of Illness Index , Anticonvulsants/therapeutic use , Chronic Disease , Epilepsy/drug therapy , Epilepsy/epidemiology , Humans , Incidence , Prognosis , Reproducibility of Results , Retrospective Studies , Risk Factors , Secondary Prevention , Sensitivity and Specificity , Temporal Lobe/surgery , Treatment Failure , Treatment Outcome , United States/epidemiology
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