ABSTRACT
The results of a study of parameters of an experimental dialyzate regeneration unit (a key functional unit of a hemodialysis apparatus with the regeneration of dialyzing solution) are discussed in the article.
Subject(s)
Hemodialysis Solutions/chemistry , Renal Dialysis/instrumentation , Calcium/blood , Chlorine/blood , Creatinine/blood , Electrochemistry , Humans , Hydrogen-Ion Concentration , Kidney Failure, Chronic/blood , Kidney Failure, Chronic/metabolism , Kidney Failure, Chronic/therapy , Kidneys, Artificial , Kinetics , Magnesium/blood , Phosphorus/blood , Potassium/blood , Sodium/blood , Urea/blood , Uric Acid/bloodABSTRACT
Radical improvements in the physiological features and self-sufficiency of hemodialysis equipment, an essential reduction of the volume of dialyzate contacting with patient's body and elimination of dependence of the equipment operation on the availability of a water-supply network can be ensured by applying a regime of circulation of a relatively small volume (3-5 l) of dialyzate through the regenerating device. The regeneration unit must eliminate the organic products of dialysis from the dialyzate and stabilize the ionic composition of the purified dialyzate according to the preset parameters. Modern methods and technical means for regenerating the used dialyzate are discussed; a regeneration unit, which ensures an electrochemical oxidation (in the used dialyzate) of nitrogen-containing organic metabolites with a subsequent sorption-type additional purification of electrochemically-processed dialyzate, is offered. The regeneration unit is made up of an electrolyser, a sorption-type additional-purification device and a gas utilizer; it eliminates organic metabolites, phosphorus, calcium and potassium from the used dialyzate and stabilizes the pH solution.