ABSTRACT
Vibroacoustic disease (VAD) is a systemic diseasethat results from long-term exposure tolow-frequency noise (LFN). VAD can cause lesionsin several organs. Noise-exposed individualsfrequently present digestive symptoms, butonly a few studies have attempted to evaluategastrointestinal lesions. The aim of this studywas to investigate the duodenal alterations inVAD, using an animal model of the disease.Adult Wistar rats were exposed to continuousLFN. After five, nine and thirteen weeks theywere sacrificed. The duodenums were studiedby light microscopy and scanning electron microscopy,and compared with those of animalskept in silence. Superficial erosions and widespreadcell death with microvilli coalescence andfusion were observed, by light and electronmicroscopy. Erosion, cellular degeneration anddeath, and microvilli destruction, reflect noise-inducedduodenal alterations in rats which may beequivalent to the ulcers and dyspeptic symptomsreported in human VAD patients (AU)
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