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Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024.
Bandeira, Antonio Carlos; Pereira, Felicidade Mota; Leal, Arabela; Santos, Sara P O; Barbosa, Ana Claudia; Souza, Marcia Sao Pedro Leal; de Souza, Daniele Ribeiro; Guimaraes, Natalia; Fonseca, Vagner; Giovanetti, Marta; Alcantara, Luiz Carlos Junior; Lessa, André Alvarez A; Saavedra, Ramon Costa; Tomé, Luiz Marcelo R; Iani, Felipe Campos M; Barros, Rivia Mary; Purificação, Sandra Maria O; de Jesus, Jaciara Prado; Fonseca, Ricardo Rosário; Araújo, Marcio Luis Valença.
Emerg Infect Dis ; 30(11): 2370-2374, 2024 Nov.
Article in English | MEDLINE | ID: mdl-39269651

ABSTRACT

We report acute Oropouche virus infections in 2 previously healthy women from a nonendemic region of Brazil outside the Amazon Basin. Infections rapidly progressed to hemorrhagic manifestations and fatal outcomes in 4-5 days. These cases highlight the critical need for enhanced surveillance to clarify epidemiology of this neglected disease.


Subject(s)
Bunyaviridae Infections , Orthobunyavirus , Humans , Brazil/epidemiology , Female , Bunyaviridae Infections/epidemiology , Fatal Outcome , Adult , Middle Aged
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