ABSTRACT
Objectives: It was evaluated epidemiological aspects of primary lip squamous cell carcinoma (LSCC) and its associationswith clinicopathological factors. Study design: This retrospective, cross-sectional study analysed a sociodemographic,clinical, and morphological data of HNSCC in a Brazilian population (n=30). Data analysis includeddescriptive statistics and bivariate analyses using the chi-square and Fishers exact tests to compare the variables.Results: The LSCC represented 10.8% of all oral cavity squamous cell carcinoma. Lip malignant disease was moreprevalent in elderly men, with male-to-female ratio of 5:1. Lower lip was more affected. It was observed high ratesof chronic solar exposure, and tobacco and alcohol drinking habits. Clinically, early TNM staging, small tumourlesions, and non-metastatic disease were predominant findings. It was identified a high frequency of well differentiatedtumor samples. Worse Karnofsky performance status was associated with cervical metastasis. Conclusions:Our findings showed that LSCC patients exhibited similar epidemiological and clinical profiles as noted in otherstudies. Still, the occurrence of metastatic disease was associated with a worse physical performance status of theLSCC patients during diagnosis (AU)
No disponible
