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J Pharm Biomed Anal ; 17(3): 419-25, 1998 Jul.
Article in English | MEDLINE | ID: mdl-9656153

ABSTRACT

The quantitative use of NMR spectroscopy was investigated by a reproducibility study of 1H-NMR integrals involving five laboratories. A significant laboratory effect was found confirming the difficulty to obtain very precise data by integration of complex signals. The reproducibility of any NMR assay measurement, which requires a high precision should be validated by an interlaboratory study.


Subject(s)
Magnetic Resonance Spectroscopy/methods , Evaluation Studies as Topic , Reproducibility of Results
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