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1.
Recenti Prog Med ; 104(7-8): 336-9, 2013.
Article in Italian | MEDLINE | ID: mdl-24042403

ABSTRACT

Neuroendocrine tumors tend to grow slowly and are notoriously difficult to localize, at least in the early stages. Metastases are in most cases already present at the time of diagnosis. Somatostatin receptor scintigraphy improves detection of small and occult NET tumors. Intraoperative probe counting with a hand-held gamma probe can identify tumors even when they are small and impalpable, but receptor positive. This advanced operative approach may improve the survival of these patients.


Subject(s)
Diagnostic Imaging/methods , Neuroendocrine Tumors/surgery , Radiography, Interventional/methods , Biomarkers, Tumor/analysis , Humans , Indium Radioisotopes , Magnetic Resonance Imaging/methods , Neoplasm Staging/methods , Neuroendocrine Tumors/diagnostic imaging , Neuroendocrine Tumors/drug therapy , Neuroendocrine Tumors/secondary , Positron-Emission Tomography/methods , Postoperative Care , Radiopharmaceuticals , Receptors, Somatostatin/analysis , Sensitivity and Specificity , Somatostatin/analogs & derivatives , Tomography, Emission-Computed, Single-Photon/methods , Ultrasonography
2.
Recenti Prog Med ; 104(7-8): 398-402, 2013.
Article in Italian | MEDLINE | ID: mdl-24042415

ABSTRACT

Tornwaldt's cyst is a benign developmental lesion of the nasopharynx, most of all midline located, originating from an outpouching of the pharyngeal mucosa caused by notocord retraction. Usually, the cyst represents an incidental finding of magnetic resonance study. The purpose of this study is to investigate the differential diagnostic aspects of Tornwaldt's cysts, making a comparison with other diseases of nasopharynx on the basis of morphological characteristics and signal, contributing to the previous statistical works.


Subject(s)
Cysts/pathology , Magnetic Resonance Imaging/methods , Nasopharyngeal Diseases/pathology , Nasopharynx/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Cysts/embryology , Female , Humans , Incidental Findings , Male , Middle Aged , Nasopharyngeal Diseases/embryology , Nasopharynx/embryology , Notochord/pathology , Retrospective Studies , Young Adult
3.
Recenti Prog Med ; 104(7-8): 350-5, 2013.
Article in Italian | MEDLINE | ID: mdl-24042406

ABSTRACT

Bone is one of the most common metastasis sites from solid tumors. Bone pain due to metastatic neoplastic growth is due to tumor infiltration and expansion of bone membranes. Treatment of acute and chronic pain represents one of the greatest problems in clinical oncology, requiring a multidisciplinary approach. This review focuses on the effectiveness of conventional diagnostic radiology and nuclear medicine for the detection, management and treatment of pain from bone metastasis.


Subject(s)
Bone Neoplasms/secondary , Pain Management/methods , Pain/etiology , Positron-Emission Tomography/methods , Radiopharmaceuticals/therapeutic use , Tomography, Emission-Computed, Single-Photon/methods , Acute Pain/diagnosis , Acute Pain/diagnostic imaging , Acute Pain/etiology , Acute Pain/radiotherapy , Bone Marrow Diseases/etiology , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/physiopathology , Bone Neoplasms/radiotherapy , Chronic Pain/diagnosis , Chronic Pain/diagnostic imaging , Chronic Pain/etiology , Chronic Pain/radiotherapy , Fluorine Radioisotopes , Fluorodeoxyglucose F18 , Humans , Multimodal Imaging/methods , Neoplasm Staging , Pain/diagnosis , Pain/diagnostic imaging , Pain/radiotherapy , Palliative Care , Radiation Injuries/etiology , Radiopharmaceuticals/adverse effects , Technetium Tc 99m Medronate/analogs & derivatives , Whole Body Imaging
4.
Recenti Prog Med ; 104(7-8): 361-6, 2013.
Article in Italian | MEDLINE | ID: mdl-24042408

ABSTRACT

Bone is the third common site of distant metastases in cancer patients. Bone metastases may have implications for prognosis, quality of life, and local and systemic therapy. Numerous imaging modalities may be used to detect bone metastases. The two main anatomical modalities are computed tomography (CT) and magnetic resonance imaging (MRI), with many variants proposed for the MRI procedure, including diffusion-weighted imaging. The two main functional modalities are scintigraphy and PET/CT, also with many variants in the radiopharmaceuticals. Aim of our paper is to review the most important radio-compounds that can be successfully used to detect and/or characterize bone metastases.


Subject(s)
Bone Neoplasms/secondary , Magnetic Resonance Imaging/methods , Radiopharmaceuticals , Tomography, X-Ray Computed/methods , Bone Marrow/pathology , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/pathology , Diffusion Magnetic Resonance Imaging , Fluorine Radioisotopes , Fluorodeoxyglucose F18 , Humans , Multidetector Computed Tomography , Multimodal Imaging/methods , Predictive Value of Tests , Radionuclide Imaging , Sensitivity and Specificity
5.
Recenti Prog Med ; 103(11): 539-41, 2012 Nov.
Article in Italian | MEDLINE | ID: mdl-23096748

ABSTRACT

Perineural tumor spread of head and neck malignancies is a well known form of metastatic disease in which a lesion can migrate away from the primary site along the cranial nerves. Nerve function can be preserved even in advanced stages of the disease, making neuroradiological assessment of perineural tumor location and extension of utmost importance, as radiological or pathological examination may reveal normal or nonspecific nerve function. Computed Tomography is useful in detecting foraminal enlargement or more destructive bone patterns. Magnetic Resonance imaging is the modality of choice because it can provide direct (nerve enlargement and enhancement) and indirect evidence of the disease (neuropathic muscular atrophy, obliteration of fat planes) owing to its superior soft-tissue contrast resolution, its multiplanar imaging and the decreased amount artifacts from dental hardware. Fat suppression images after contrast injection are mandatory to better detect nerve enhancement. We report the case of a female patient with perineural diffusion along the ophthalmic branch. This clinical picture is very rare, compared to those involving the mandibular and maxillary branches of the fifth cranial nerve.


Subject(s)
Cranial Nerve Neoplasms/pathology , Head and Neck Neoplasms/pathology , Trigeminal Nerve Diseases/pathology , Trigeminal Nerve , Aged , Female , Humans , Neoplasm Metastasis
6.
Recenti Prog Med ; 103(11): 417-21, 2012 Nov.
Article in Italian | MEDLINE | ID: mdl-23096723

ABSTRACT

Technical advances in computed tomography (CT), including helical CT and multidetector CT, have resulted in an improved ability to evaluate the small intestine. CT examination of the small bowel requires the use of dedicated techniques for optimal evaluation of inflammatory bowel disease in order to select the most appropriate therapeutic strategy for the individual patient and to monitor disease progression over time.Although intraluminal contrast media combined with intravenous iodinated contrast agents with a biphasic injection protocol provide good visualization of the typical lesions of the disease, accurate estimation of the degree of disease activity can only be achieved with nuclear imaging. Owing to continuous technical improvements, magnetic resonance imaging is expected to play an increasing role in the near future. However, in selected patients, three-dimensional endoanal ultrasonography remains the gold standard technique for assessing the anal sphincter and the recto-anal junction.


Subject(s)
Inflammatory Bowel Diseases/diagnostic imaging , Multidetector Computed Tomography , Humans
7.
Recenti Prog Med ; 103(11): 455-8, 2012 Nov.
Article in Italian | MEDLINE | ID: mdl-23096731

ABSTRACT

CT enteroclysis is an imaging technique that allows better visualization of the small bowel than standard abdomino-pelvic CT. It is more accurate than CT enterography and provides complementary diagnostic information to digestive endoscopy. Multiplanar reconstruction allows better evaluation of the diseases arising from the small bowel wall, or from surrounding organs, resulting in increased accuracy and effectiveness of this imaging technique. CT enteroclysis often enables a comprehensive assessment of small bowel disease, allowing a definite diagnosis and characterization of intestinal bowel disease, or of other related pathological conditions.


Subject(s)
Contrast Media , Intestine, Small/diagnostic imaging , Tomography, X-Ray Computed/methods , Humans
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