1.
Ann Acad Med Singap
; 50(2): 171-173, 2021 02.
Article
in English
| MEDLINE
| ID: mdl-33733260
ABSTRACT
Recent research in atopic dermatitis (AD) has identified it to be a heterogeneous inflammatory skin disorder of different endotypes (immune polarisation of T-cell subsets and genetic mutations) underlying various phenotypes (age of onset, ethnicity, disease severity, etc.). The corresponding heterogeneity in underlying patho-mechanisms of the disease has resulted in an impetus towards an endotype-driven management of AD. We propose a practical approach that is based on classifying AD patients into intrinsic and extrinsic phenotypes and their corresponding underlying endotypes. This approach aims to provide a practical method that integrates recent understanding of AD pathogenesis for a targeted endotype-driven management of AD.
Subject(s)
Dermatitis, Atopic , Eczema , Dermatitis, Atopic/therapy , Humans , Mutation , Severity of Illness Index , Skin
2.
Dermatitis
; 32(2): e35-e36, 2021.
Article
in English
| MEDLINE
| ID: mdl-32804685
3.
Discoid lupus erythematosus precipitated by topical diphencyprone immunotherapy for alopecia areata.
JAAD Case Rep
; 6(8): 747-750, 2020 Aug.
Article
in English
| MEDLINE
| ID: mdl-32715069